extra passmed questions 3 Flashcards
what is meckels diverituclum?
- pouch
- may be lined with ectopic gastric mucosal tissue
- produce bleeding
- congenital
what type of shock most commonly occurs following a spinal cord transection?
- neurogenic shock
- vasolidation –> decreased preload –> decreased cardiac output –> hypotension
- patient will need vasopressors !
- to reverse profound v.dilation
which pancreatic enzyme would you use to diagnose acute pancreatitis?
- serum lipase has longer half life than amylase
- may be useful in late presenting patients
3 - 4.4cm
small aneurysm
action
rescan every 12 months
4.5 - 5.4cm
medium aneurysm
action:
rescan every 3 months
> 5.5cm
large aneurysm
action:
refer within 2 weeks to vascular surgery
next appropriate step in management of patient with long saphenous vein superficial thrombophlebitis?
USS
to exclude underlying DVT
TX: bed red and analgesia
absent T waves
hypokalaemia
Reynold’s pentad is
charcots triad
- RUQ pain
- jaundice
- fever
and
- hypotension
- confusion
Beck’s triad
- hypotension
- raised JVP
- muffled heart sounds
CARDIAC TAMPONADE
Cushing’s triad
- irregular and decreased resp rate
- bradycardia
- hypertension
RAISED INTRACRANIAL PRESSURE
45 y/o female
pc: 3cm breast lump
ER+, HER2- tumour, confined to breast
describe this case and next stage of management:
HER2-
- hormone receptor positive cancers
- grow faster than HER2+ cancers
ER+
- increased aggressiveness
this patient has a fast growing aggressive cancer.
management depends on size of tumour.
If < 4cm ——> WIDE LOCAL EXCISION
if > 4cm ——> MASTECTOMY
abdominal pain
- presents post meal
- nausea vomiting
- pain radiates to shoulder
indicative of:
biliary colic
- esp if obs are normal
investigation for suspected bowel perforation
erect chest x-ray
28 y/o male
pc: locally advanced mucinous carcinoma of the caecum
oe: scanty polyps in remaining colon
fhx: father died from colorectal cancer aged 34
likely diagnosis:
Lynch syndrome
aka HNPCC
Amsterdam criteria used to identify families at risk
mode of inheritance of BRCA gene
autosomal dominant
so 50% chance of passing this on
management for anal fissures not responding to conservative management:
sphincterotomy
anal fissures
- longitudinal or elliptical tears at squamous lining of distal anal canal
in management of ER +ve beast cancer what drugs are used:
ER+ = aggressive
Either:
- aromatose inhibitors
- anastrozole
- side effect: osteoporosis - anti-oestrogen medications is Selective oEstrogen Receptor Modulators (SERM)
- tamoxifen
- side effect: VTE, endometrial cancer
causes of unilateral hydronephrosis:
PACT
Pelvic-ureteric obstruction (congenital or acquired)
Aberrant renal vessels
Calculi
Tumours of renal pelvis
causes of bilateral hydronephrosis:
SUPER
Stenosis of the urethra
Urethral valve
Prostatic enlargement
Extensive bladder tumour
Retro-peritoneal fibrosis
Investigations and management for hydronephrosis
- USS first line
- IVU (intravenous urogrpahy) assess position of obstruction
- Antegrade or retrograde pyelography- allows treatment
- if you suspect stones: CT scan
management
- remove obstruction
- acute: nephrostomy
- chronic: ureteric stent
What is the mechanism of action of goserelin in prostate cancer?
GnRH agonist
- provides negative feedback to the AP
28 y/o hypertension + haematurua + polycytheaemia, CT shows L renal mass
renal adenocarcinoma
68 y/o recurrent episodes of LHS ureteric colic + haematuria + dilatation of renal pelvis
transitional cell carcinoma
A 4-year-old boy presents with haematuria and on examination is found to have a right sided renal mass.
Wilms tumour (nephroblastoma)