extra Flashcards

1
Q

can you peform a peak flow sat or standing

A

yes - so chest is expanded and not compressed by poor posture

highest reading is recorded

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

diagnostic level of sweat test for CF

A

over 60 mmol/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

foul smelling sputum , recurrent fever and histroy of stroke ( risk of aspiration) and finger clubbing

A

lung abcesss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is ARDS

A

In ARDS, the alveolar capillaries become more permeable, leading to fluid accumulation in the alveoli. This is non-cardiogenic pulmonary oedema. There are several underlying pathophysiological mechanisms that have been suggested including pro-inflammatory cytokines and chemokines, as well as neutrophilic infiltration. The commonest finding in ARDS is hypoxaemic respiratory failure. The commonest clinical presentation is acute-onset cyanosis, dyspnoea and tachypnoea.

ARDS has a mortality rate of 30–45% and has significant morbidity in the population that does survive. The American-European consensus conference has developed a number of criteria for recognising ARDS including: <1 week onset of a known risk factor, pulmonary oedema, non-cardiogenic, and pO2/FiO2 ratio <40 (a defining feature).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

culmative damage and repeated chest infection lead to distal airway dilation - bronchiectasis - sign of CT

A

signet ring sign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what would suggest life-threatening asthma

A

Normal PaCO2 (4.6 - 6.0kPa)
intially low due to hyperventilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

4 diangostic criteria for ARDS

A

bilateral diffuse infiltrates -alveolar
less than 7 days
P02:Fi02 undre 200
pulmonary capillary wedge pressure under 18mmHg - elevated left atrial pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

A 28-year-old Afro-Caribbean woman presents to the emergency department with shortness of breath, painful red lesions on her shins and pain in her ankle joints.

Vitals signs show a temperature of 38.4. A chest X-ray is ordered and shows bilateral hilar lymphadenopathy.

Which of the following is the most likely diagnosis?

A

This lady is presenting with acute sarcoidosis, also known as Lofgren’s syndrome. This is the combination of bilateral hilar lymphadenopathy, erythema nodosum, acute polyarthritis and fever. Sarcoidosis is also more common in those of Afro-Caribbean heritage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

hF mamagement

A

Captopril, Bisoprolol and Pneumococcal vaccination

This is the correct answer. The patient has signs, symptoms and chest x-ray are consistent with left sided heart failure. Patients with chronic heart failure are managed with angiotensin converting enzyme inhibitors (ACEi) and beta blockers as first line management. ACE-i work on the renin angiotensin aldosterone axis to dilate blood vessels and decrease blood pressure. Beta blockers reduce the heart rate and improve the ejection fraction as the heart can fill more efficiently. Additionally, the pneumococcal vaccine is given to patients with chronic heart failure and those over the age of 65 to reduce the risk of developing a streptococcus pneumoniae pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

perihilar and central lesion for cancer what cancer

A

SCLC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

cavitating lesion in lung , haeompytyss and ALARM symtpoms - Alarm symptoms are vomiting, bleeding or anemia, abdominal mass or unintended weight loss, and dysphagia VBAD

A

SCLC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

precedding flu-like illness, dyr cough and erythema multiforme ( target shaped lesions) anaemia and SOB what is atypcial penumonia

A

mycoplasma pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

erythema multiforme

A

target shaped lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what eye condition is associated with sarcodiosis

A

anterior uveitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

anxiety-panic attack

A

The patient is presenting with shortness of breath but is saturating well at 15.0 kPa (not hypoxic - therefore by definition not in respiratory failure). Their pH and CO2 are however quite deranged - however in-keeping with the normal physiological response to breathing more quickly (blowing off more CO2 and as a result your carbonic anhydrase equation shifts and the patient becomes more alkalotic). The normal bicarbonate indicates that the cause of this alkalosis is respiratory in origin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

are the pneumococcal and influenza vaccines live

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

marfans disease increases the risk of

A

pnemothorax and aortic dissection or rupture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

A 43-year-old gentleman is assessed in A&E. He presents with a one week history of shortness of breath, non-productive cough and fevers. He has a past medical history of HIV and says he had stopped taking his antiretroviral medication 6 months ago due to side-effects. On initial assessment, he appears unwell, tachypneic and has oxygen saturations of 90% on air.

His chest X-ray is as follows:

A

This patient has become short of breath and febrile on a background of uncontrolled HIV. It is likely that he is immunocompromised. He is hypoxic and his chest X-ray shows bilateral ground glass like opacification most prominent in the lung bases. This is highly suspicious for PCP and should be treated accordingly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

bronchiectasis tx

A

chest physio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

tx for adenocarcinoma

A

loboectomy
This is correct. It is the definitive management of a patient with a curative adenocarcinoma (non-small cell lung cancer), patients must undergo pulmonary lung function tests prior to treatment with surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

tx for adenocarcinoma

A

loboectomy
This is correct. It is the definitive management of a patient with a curative adenocarcinoma (non-small cell lung cancer), patients must undergo pulmonary lung function tests prior to treatment with surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

symptoms of facial plethora, distended neck veins, a headache and have a positive Pemberton’s test

A

SVC obstruction
stent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

A 30 year old woman develops a five day history of a productive cough and high fever. She also has been short of breath progressively over the past few days.

Furthermore, she complains of painful blue fingers and toes over the past two days, which occur whenever she is outdoors and the temperature has dropped. Yet when indoors she has noticed they return to their normal colour.

What additional findings would you expect to see on examination?

A

Multiple erythematous papules with deeply erythematous borders

This is correct. The patient has signs of cold autoimmune haemolytic anaemia and a pneumonia. The pneumonia most commonly associated with this autoimmune condition is mycoplasma pneumonia. Mycoplasma pneumonia can also present with erythema multiforme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

A 30 year old woman develops a five day history of a productive cough and high fever. She also has been short of breath progressively over the past few days.

Furthermore, she complains of painful blue fingers and toes over the past two days, which occur whenever she is outdoors and the temperature has dropped. Yet when indoors she has noticed they return to their normal colour.

What additional findings would you expect to see on examination?

A

Multiple erythematous papules with deeply erythematous borders

This is correct. The patient has signs of cold autoimmune haemolytic anaemia and a pneumonia. The pneumonia most commonly associated with this autoimmune condition is mycoplasma pneumonia. Mycoplasma pneumonia can also present with erythema multiforme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

squmaous cell carcinoma linked to what hormone

A

parathyroid hormone related peptide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

squmaous cell carcinoma linked to what hormone

A

parathyroid hormone related peptide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

how does sarcoidosis lead to hypercalcaemia

A

Sarcoidosis is associated with the formation of granulomas which causes hypercalcaemia via uncontrolled synthesis of 1,25-dihydroxyvitamin D3 by macrophages

26
Q

someone has superior vena cava obstruction what is the first step management

A

dexamethasone - reduce swelling to secure the airway - 8mg

27
Q

prominent neck veins and elevation of both arms results in facial engorgement, consistent with a diagnosis

A

SVCO

28
Q

hypercalcaemia management - either in lung cancer from release of PTHrP or osteolytic bone lesions

A

IV fluids
IV bisphosphonate - 2-4 day response

28
Q

hypercalcaemia management - either in lung cancer from release of PTHrP or osteolytic bone lesions

A

IV fluids
IV bisphosphonate - 2-4 day response

29
Q

Sepsis of pulmonary origin is the most common underlying cause of ARDS which is a life-threatening non-cardiogenic pulmonary oedema. when does this occur

A

one week of an established risk factor and presents with new bilateral opacities on the chest X-ray

30
Q

sings of high Ca

A

polyuria, polydipsia, constipation and confusion

squamous cell carcinoma associated with hypertrophic pulmonary osteoarthropathy HPOA - affects hands and feet

31
Q

birds - pneumonia to humans

A

chlamydia psittaci

31
Q

birds - pneumonia to humans

A

chlamydia psittaci

31
Q

birds - pneumonia to humans

A

chlamydia psittaci

32
Q

birds - pneumonia to humans

A

chlamydia psittaci

33
Q

This is correct. The patient has a productive cough with haemoptysis, finger clubbing and bilateral coarse inspiratory crepitations which point towards bronchiectasis. The young patient demographics makes a congenital cause more likely. Furthermore, cystic fibrosis is a multi-system condition which can affect pancreatic function causing both exocrine and endocrine insufficiency

A

CF

34
Q

bronchial obstruction

A

salbutamol

35
Q

type 1 failure

A

liaise ICU - O2 support

36
Q

history of stroke predispose to what

A

aspiration pneumonia

36
Q

history of stroke predispose to what

A

aspiration pneumonia

36
Q

history of stroke predispose to what

A

aspiration pneumonia

37
Q

over 40 unexplained haemoptysis -

A

2ww urgent referal

38
Q

3 or more exacerbations per year - optimal medical management

A

long term prophylactic antibiotics

39
Q

non-ceasating vs ceaseating granulomas

A

non - sarcoidosis
ceaseating - TB

40
Q

CF and complaining of steatorrhoea - pale and oily stool hard to flush away

A

creon - pancrelipase

40
Q

CF and complaining of steatorrhoea - pale and oily stool hard to flush away

A

creon - pancrelipase

41
Q

penumonia - myalgia , headaches, dry cough , high fevers , low sodium

A

legionella pneumophilia

42
Q

penumonia assoicated with herpes laialis and lobar penumonia

A

strep

43
Q

bilateral coarse crackles means

A

thick mucus production and reduced clearance

44
Q

near fatal - elevated CO2
life threatening - back to normal CO2

A
44
Q

near fatal - elevated CO2
life threatening - back to normal CO2

A
45
Q

what abx for aspiration pneumonia

A

metronidazole

46
Q

lambert eaton syndrome caused by

A

voltage gated calcium chaneel antibodies

47
Q

methotrexate can cause

A

pneumonitis

48
Q

COPD with asthmaitic feature need LABA and ICS
without

A

LABA and LAMA

49
Q

brain tumour in palliative care what tx would you get- pallative

A

dexamethasone 8-16mg per day

50
Q

opiate of choice for patients with renal impairement

A

oxycodone - diabetic neuropathy

oxycodone is stronger than morphine

51
Q

low VQ ratio means what compared to high V/Q ratio

A

Low V/Q: areas that have poor ventilation with oxygen but are well perfused by blood. E.g. bronchoconstriction (Asthma), airway collapse in emphysema, mucus plug, congestive cardiac failure

High V/Q: areas of the lung with adequate ventilation but are lacking blood perfusion E.g. Pulmonary embolism.

52
Q

lung cancer normally mets too

A

Lung cancer most commonly metastasises to the brain, bone, liver and adrenals.

53
Q

pulmonary hypertension on ECG

A

P pulmonale is a right atrial abnormality that is seen on ECG as tall, peaked P waves. It is a feature that can be seen on ECG in patients with pulmonary hypertension, as it is a cause of right atrial enlargement.

54
Q

resp alkalosis seen in what overdose

A

aspriin

55
Q

resp patients noramlyl given 15L/minute Oxygen via a non-rebreathe mask
unless chronic CO2 retainer such as COPD what do you do for oxygen

A

28% oxygen via Venturi mask

This patient has severe COPD and is a chronic CO2 retainer as shown by the raised HCO3 and base excess on his arterial blood gas. His target oxygen saturations should be 88-92%. By over-oxygenating him and achieving saturations of 96%, he is losing his hypoxic drive and is hypoventilating. This is shown by his reduced work of breathing and looking calmer, which is in fact a decreasing level of consciousness due to CO2 narcosis. He should be switched onto 28% oxygen via a Venturi mask with an aim of achieving target oxygen saturations of 88-92%

56
Q

RF for cholangiocarcinoma

could get excroiations over skin

A

This patient has three of the key risk factors for cholangiocarcinoma (a tumour arising from the bile duct epithelium): age >50, ulcerative colitis and PSC. She also has painless jaundice, weight loss and itching, all of which are commonly seen in cholangiocarcinoma.

57
Q

bladder cancer 2www

A

patient is aged 45 years or over and has painless visible haematuria