experimental skills Flashcards
when can’t you take propranolol
when heart rate above 70bpm
history of asthma or breathing problems
personal or family history of heart problems
contra-indications of propranolol
asthma, pregnancy, diabetes liver disease hypersensitivity
single dose of propranolol
40mg
effects of propranolol
small reduction in heart rate, systolic and diastolic blood pressure
feeling of tiredness and reduced ability to perform exercise
side effects of propranolol
bradycardia, hypotension, bronchospasm peripheral vasoconstriction sleep disturbances
contraindications of salbutamol
hypertension or heart disease diabetes pregnancy hyperthyroidism -->cannot take if on diuretics, corticosteroids or theophylline
effects of salbutamol
flushing of face
hand tremor
rise in systolic pressure and fall in diastolic blood pressure
small tachycardia- may have palpitations
side effects of salbutamol
fine tremor
headache
peripheral vasodilation
tachycardia and palpitations
when can you take glyceryl trinitrate
have to have blood pressure greater than 100/60
contraindication of GTN
hypotension anaemia glaucoma hypothyroidism pregnancy
effects of GTN
flushing of face
fall in systolic and diastolic blood pressure
small tachycardia and palpitations
headache
side effects of GTN
headache
flushing
dizziness
tachycardia
agonist
drug that once binds produces a similar response to an endogenous ligand
antagonist
decrease the response of an agonist or biological ligand
agonist for beta 1 receptor
cardiac
noradrenaline
adrenaline
isoprenaline
antagonist for beta 1 receptor
propranolol
agonist for beta 2 receptor
trachea smooth muscle
noradrenaline
adrenaline
isoprenaline
antagonist for beta 2 receptor
propranolol
agonists for vans deferens and aortic smooth muscle
noradrenaline, adrenaline
alpha1- phenylephrine
alpha2- clonidine
antagonists for vans deferens and aortic smooth muscle
alpha 1- prazosin
alpha 2- yohimbine
illeal smooth muscle agonist
muscarinic receptors
carbachol
antagonist for illeal smooth muscle
atropine
accommodation
changing shape of lens depending on near/far objects to focus image on retina
bone conduction
tuning fork held to subjects skull, sound can reach the cochlea independently of the middle ear
conductive deafness
subject will be deaf to ordinary air conduction but shows no deafness to bone conduction
due to disease in middle ear interfering with transmission of sound
sensorineural deafness
subject is dead to both air and bone conduction
dut to injury or degeneration of nerve elements on cochlea or auditory nerve
causes of conductive deafness
middle ear infections- serous ottis media
damage to ossicles
thickening of perforation of tympanic membrane
otosclerosis (ossicle immobile due to growth of bone)
causes of sensorineural deafness
acoustic neuroma- benign tumour of auditory nerve
toxic degeneration of auditory nerve
acoustic trauma
viral infections of inner ear or auditory nerve
meningitis