EXPERIMENT 15 HBsAg RAPID TEST Flashcards

1
Q

size of enveloped Hepa B virus

A

42 mm

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2
Q

genome of hepa B

A

dsDNA

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3
Q

earliest serological marker indicating acute/chronic infection

A

HBsAg

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4
Q

principle of the test

A

immunochromatography (solid phase “sandwich” immunoassay)

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5
Q

2 stages of infection

A

acute: general flue-like
progressive: hepatomegaly, jaundice, dark urine, ight feces

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6
Q

initial lab test

A

elevation in billirubin and liver enzymes (ALT)

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7
Q

diagnosis of hepa B

A

realtime PCR- sensitive as few as 10 copies per mL
HBV DNA viral load

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8
Q

serologic markers

A

HBsAg- active
HBeAg- infective
IgM anti HBc- current/recent/acute
total anti HBc- current/past
anti HBe- recovery from hepa B
anti HBs- immunity
HBV DNA

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