EXPERIMENT 15 HBsAg RAPID TEST Flashcards
1
Q
size of enveloped Hepa B virus
A
42 mm
2
Q
genome of hepa B
A
dsDNA
3
Q
earliest serological marker indicating acute/chronic infection
A
HBsAg
4
Q
principle of the test
A
immunochromatography (solid phase “sandwich” immunoassay)
5
Q
2 stages of infection
A
acute: general flue-like
progressive: hepatomegaly, jaundice, dark urine, ight feces
6
Q
initial lab test
A
elevation in billirubin and liver enzymes (ALT)
7
Q
diagnosis of hepa B
A
realtime PCR- sensitive as few as 10 copies per mL
HBV DNA viral load
8
Q
serologic markers
A
HBsAg- active
HBeAg- infective
IgM anti HBc- current/recent/acute
total anti HBc- current/past
anti HBe- recovery from hepa B
anti HBs- immunity
HBV DNA