Experience Dependent Plasticity Flashcards
What is Hebb’s postulate?
Synchronized activity pre & post synaptically leads to retention of those synapses
Synaptic modification leads to what 2 behavioral consequences?
-Behaviors not initially present are shaped by life’s experience
- Irrelevant or erroneous behaviors are removed
What is pruning?
how synapse are destroyed
What is a critical period?
Time when experience & neuronal activity is ideal to develop a behavior
What do critical periods rely on?
Circuitry of the cortex
What is ocular dominance column?
Visual cortex is organized as alternating bands
What happens to ocular dominance column when both eyes are sutured?
No ocular dominance columns formed
What happens when one eye is sutured?
Dominance of one types of ocular dominance column
What would happen is eyes are held open?
Ocular dominance columns form but all are weaker
What is amblyopia?
Cortical blindness, caused by decreased light exposure & leads to poor binocular vision
What is Esotropia?
Cross eyed
What is exotropia?
Wall eyed
What does esotropia & exotropia lead to?
Double vision
- One eye will have inputs to cortex remain while those of the other eye will diminish
Does taste have a critical period?
no
What neurotransmitter signaling are critical periods highly dependent on?
Glutamate signaling to NMDA receptors
Inhibitory signaling via GABA
