EXOTIC DISEASES Flashcards
Neurological disorder affecting cattle
BOVINE SPONGIFORM ENCEPHALOPATHY
misfolded proteins
Prions
in cases of BOVINE SPONGIFORM ENCEPHALOPATHY, CS signs is observable only when
mature (2-8 yrs)
T/F: PH doesn’t have an official BSE risk status
T
case fatality rate of Bovine Spongiform Encephalopathy
100%
incubation period of Bovine Spongiform Encephalopathy
2-8 yrs
in cases of Bovine Spongiform Encephalopathy, risk is greatest in ____
first 6 months of life
MOT of Bovine Spongiform Encephalopathy
ingestion,
Foodborne exposure to prions
infective tissues to cattle in cases of Bovine Spongiform Encephalopathy (hint: BSR)
brain,
spinal cord,
retina
4 clinical exam tests to determine Bovine Spongiform Encephalopathy
a) bang test
b) flash test
c) clipboard test
d) stick test
prions replicate in ___
peyer’s patches
Gold standard for surveillance programs for BSE
Immunohistochemistry
causative agent of Enzootic abortion of ewes
Chlamydophila abortus
major source of infection of Enzootic abortion of ewes
vaginal discharge,
placenta, and
aborted fetus
2 MOT of Enzootic abortion of ewes
Ingestion organisms,
aerosols
infections of Enzootic abortion of ewes activates only during ____ and _____
pregnancy and parturition
what phase of pregnancy does abortion occur in cases of Enzootic abortion of ewes
late pregnancy
clinical signs of Enzootic abortion of ewes are more severe in what animal species
sheep
persistent infection of Enzootic abortion of ewes occurs in the ____
reproductive tract
causative agent of Johne’s disease
mycobacterium avium
Johne’s disease is widespread in what continent
Europe
incidence of Johne’s disease is high in ____
intensive systems
Johne’s disease is primarily spread/shed via ___
feces
infection of Johne’s disease is (acute VS chronic)
chronic
Primary route of transmission of Johne’s disease
nursing
Occurs from an animal that has been infected by Johne’s disease for a long time
Intrauterine infection
2 Other routes of transmission of Johne’s disease
vectors s (oriental cockroaches, earthworms, adult dipterans, ovine trichostrongylid larvae),
Amitraz dips
age of animals at risk of Johne’s disease
under 30 days of age
Johne’s disease is associated with ____ disease in humans
Crohn’s disease
Most pathogenic viral dz of small ruminants
NAIROBI SHEEP DISEASE
Nairobi sheep disease is transmitted by ___
ticks
Nairobi sheep disease endemicity
East & Central Africa
antibodies of Nairobi sheep disease have been detected in
Southern & Northeastern Africa,
Sri Lanka
variant of Nairobi Sheep disease virus in Asia
Ganjam virus
2 vectors of Nairobi sheep disease
Brown ear tick/ Rhipicephalus appendiculatus,
Bont tick/ Amblyomma variegatum
main organ affected by Nairobi sheep disease
Abomasum
3 specimens for diagnosis of Nairobi sheep disease
blood,
mesenteric LN,
spleen
Q fever is associated with what organism
Coxiella burnetii
3 main reservoirs of Q fever
cattle,
sheep,
goat
2 transmissions of q fever
- sylvatic
- domestic cycle
main MOT of q fever in humans
inhalation
transmission of q fever occurs during ___
parturition
