exemplify review sessions 5-8

Question 1

does ivabradine reduce heart rate but does not reduce blood pressure

Answer 1

yes

Question 2

amiodarone is a class 3 antiarrhythmic that

Answer 2

acts on sodium channels, potassium channels, calcium channels and as a non-competitive beta blocker

Question 3

What does the class 1c antiarrhythmic agent flecainide do

Answer 3

increase P-R interval
Increases AP duration
Slows tissue conduction during phase 0

Question 4

why should an antiarrythmic agent such as a beta blocker be given alongside flecainide in atrial flutter

Answer 4

to prevent the possibility of v tach

Question 5

Is Digoxin’s rate limiting action independent of Na/K/ATPase

Answer 5

Yes- indirect via parasympathetic action

When used in heart failure its action is directly via the Na/K/ATPase and associated calcium activity

Question 6

Action of alteplase

Answer 6

increases the conversion of plasminogen to plasmin which results in fibrinolysis

Question 7

GLP-1 agonists like exenatide actions

Answer 7

Increase insulin secretion
Decrease glucagon secretion
Decrease gastric emptying (to reduce post prandial glycaemia)

Question 8

When may clopidogrel be prescribed after STEMI

Answer 8

In addition to aspirin for up to 12 months

Question 9

What does PGI2 do

Answer 9

inhibit platelet aggregation

Question 10

What does TXA2 do

Answer 10

contribute to platelet aggregation