excitation of skeletal muscle (midterm 1) Flashcards
what does the nerve fiber form
branching nerve terminals that go into the surface of the muscle fiber and are outside the muscle fiber plasma membrane
what is the structure of the nerve fiber called
motor end plate
what surrounds the axon
myelin sheath
what are the safety factors of excitation of skeletal muscles
end plate potential < threshold => rarely fatigue
what’s the end plate potential
local potential caused by Na+ flux
what is curate
a drug that blocks the gating action of acetylcholine on the acetylcholine channels by competing for the acetylcholine receptor sites
what is botulinum toxin
a bacterial poison that decreases the quantity of acetylcholine release by the nerve terminals
when is Ca++ too low for A-M binding
normal - ~10^-2 M
when is Ca++ 10x higher than needed
excitation - ~20^-2 M
when does muscle contraction occur
during Ca++ alone and continuous contraction requires continuous Ca++ release