Exam1 Flashcards
Why do we care about osmole?
Because the greater the osmoles the greater tho osmotic pressure
What is osmolarity?
It is osmoles per liter Osm/L
What is an equivalent?
It is the amount of charged solute in solution ex: CaCl2= 2 Eq of Ca and 2 Eg of CL
What are the major ions in ECF?
Major cation= Na+
Major anion= Cl- and HCO3-
What does ionized calcium mean?
It means that it is free calcium, not bound and it is the active form that can interact with other substances
Acid base balance is managed by?
Managing how much calcium is bound and how much is free (participates in reactions)
What is the perfect osmolarity in animal species?
290-300 mOsm/L
What are the major ions in ICF?
Cation= K+
Major anions= organic phosphates and proteins
What are the major ions in ICF?
Cation= K+
Major anions= organic phosphates and proteins
The most common mechanism of transport in cells is?
Sodium potassium pump
Sodium goes out of the cell
Potassium goes inside the cell
Which direction Ca+ goes?
Out of the cell
Na+ difference allows what?
Upstroke of action potential in nerve and muscle cells
What allows the membrane to be permeable to lipid-solubles (e.g., CO2, steroid hormones, O2, FA)
Glycolipids, lipids, and proteins.
Simple and facilitated diffusion is?
Using a protein to get across, the substance can get across (lipid soluble)
Moving into a gradient of higher concentration we use?
ATP
Primary (directly uses energy) or secondary transport (indirectly uses energy)
Simple diffusion
moves to less concentration
What is the driving force?
Concentration gradient
Partition coefficient
The greater the solutes, solubility in oil the higher the partition coefficient and more easily can diffuse
Diffusion coefficient
Has to do more with the radius of sollute and viscosity. Small solute in non-viscous solution more easily can move across the cell membrane
Surface area
The more surface area you have the higher the diffusion rate (more chances to get across)
What are the consequences of charge when an ion is diffusing?
Positive to where a lot positive already there, then the ion is going to slow down.
A diffusion potential can be created when ion is going into less concentration of same
Does facilitated diffusion required energy?
No, it does not require an input of energy
However, there is a limit number of carriers. When the concentration is