exam review Flashcards

1
Q

how does glucose contrivute to fa

A

glycerol

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2
Q

how do amino acids contribute to fa

A

oxoloacetate and pyruvate

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3
Q

in adipocytes, what does glucose do

A

metabolized to make acetyl coa, converted to fatty acids

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4
Q

what acts of TAG in chylomicrons to cause free fatty acids and MAG to enter the adipocyte

A

lipoprotein lipase

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5
Q

are ketone bodies futher oxidized in the liver

A

no

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6
Q

complex lipids

A

lipids that contain fatty acids

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7
Q

types of complex lipids

A

storage lipids and membrane lipids

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8
Q

lipids that do not contain fatty acids

A

cholesterol, vitamins, pigments, etc

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9
Q

omega 3 fa

A

alpha linolenic acid
epa
dha

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10
Q

omega 6 fa

A

lineleic acid
arachidonic acid

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11
Q

a-linolenic acid

A

18:3 n-3

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12
Q

linoleic acid

A

18:2 n-6

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13
Q

which type of omega fa cause the pro-inflammatory cox 2

A

6

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14
Q

which type of omega fa cause the anti-inflammatory cox 2

A

3

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15
Q

olestra is _____ linked by _____ bonds to several long chain FA

A

sucrose, ester

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16
Q

why cant enzymes break down olestra

A

cannot cleave fatty acid groups from sucrose backbone

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17
Q

what does olestra inhibit the absorption of

A

fat soluble vitamins (ADEK)
cartenoids

18
Q

what enzymes does orlistat inhibit

A

gastric and pancreatic lipase

19
Q

lipolysis

A

process by which triaglycerols break down via hydrolysis into their constituent molecules: glycerol and free fatty acids

20
Q

where does the glycerol produced by lipolysis go

A

source of carbon for gluconeogenesis in the liver

21
Q

draw beta oxidation

22
Q

steps of odd chain fatty acid oxidation

A

propionyl coa -> methylmalonyl coa -> succinyl coa

23
Q

what can pass straight into the mitochondiral matrix

A

short chian fatty acids

24
Q

which type of fatty acids need a carrier to unter the mitochondiral matrix

A

long chain

25
where is carnitine from
lysine and methionine
26
why would free glycerol not be used in adipocytes
they dont contain the enzyme glycerol - 3 - phosphasphatease
27
does cholesterol produce energy
no
28
what is cholesterol used for
membrane stability synthesis of bile acids, sex hormones, vit d, corticosteroids
29
cholesterol bad stuff
hypercholesterolemia (high blood cholesterol) dysregulation of cholesterol synthesis athereosclerosis (heart attack or stroke)
30
what is most of the cholesterol in the diet
ester, must be hydrolyzed
31
how does cholesterol pass through the lumen enterocyte membrane
micelles facilitated by energy independent transporter protein (NPC1L1)
32
types of fatty acid transport system proteins
FATP FABP FAT (fatty acid translocase)
33
VLDL mostly
triacylglycerol
34
LDL mostly
cholesterol
35
HDL mostly
protein
36
chylomicron mostly
triacylglycerol
37
does fatty acid absorption into enterocyte require energy
no
38
what fatty acids passively diffuse into the enterocytes
SCFA
39
types of fatty acid binding proteins
FATP, FABP, FAT
40
where does lipolysis happen
cytoplasm of adipocytes