Exam One Study Guide Flashcards
Action: increase linear height in children
Somatotropin (STH)
Means: protein formation, cell proliferation, differentiation
Somatotropin (STH)
Action: metabolism in adults
Human Growth Hormone (hGH)
Action: metabolism of glucose, proteins, and fat
Adrenocorticotropic or corticotrophin (ACTH)
Action: mammary gland development and milk production
Lactotropes - prolactin hormones
Action: stimulate growth of ovaries and testes
Gonadotropins
Means: stimulates the production of LH and FSH
Gonadotropins
Action: stimulates melanocytes
Melanotropin
What is the site for hGH or STH?
Adenohypophysis (PPP)
Means: Stimulate protein anabolism (carbohydrate and lipid catabolism)
hGH and STH
What diseases can be caused by issues with hGH and STH?
Gigantism, acromegaly
What are symptoms of gigantism and acromegaly?
Bossing of forehead, headache, tissue proliferation
What is the site for somatostatin (SS)?
Hypothalamus, stomach, small intestine, D cells of pancreas (PPP)
Action: decrease synthesis of STH, decrease insulin, decrease glucagon
Somatostatin (SS)
Action: increase BP, immunity, blood glucose
STH
What is a disease cause by issues with somatostatin (SS)?
Pituitary tumor
What is the site for insulin like growth factor (IGF1) or somatomedin (SM)?
Liver, kidney (PPP)
Action: facilitates with increase of linear height
Insulin like growth factor (IGF1) or somatomedin (SM)
Means: stimulates protein anabolism, osteoblast cells, and increase of cellular uptake of glucose
IGF1 or somatomedin (SM)
What is the site for luteotropin (LTH)?
Adenohypophysis (PPP)
Action: stimulates development of mammary glands and stimulates milk production
Luteotropin (LTH)
Means: affects the lobular and alveolar ducts of mammary glands (BIG 4 MEANS)
Luteotropin (LTH)
What is the most powerful controller of decreasing sex hormones?
Luteotropin (LTH)
What can be a consequence of high luteotropin?
Milk production in both sexes
What is the site for melanotropin (MSH)?
POMC cells, pars intermedia, adenohypohysis (PPP)
Action: stimulate pigmentation
Melanotropin (MSH)
Means: stimulate melanocytes, increase memory (BIG 4 MEANS)
Melanotropin (MSH)
Excessive pigmentation is a symptom during what normal process?
Pregnancy
What is the site for corticotropin adrenocorticotropin (ACTH)?
POMC cells, adenohypophysis (PPP)
Action: Stimulate and develop the adrenal glands
ACTH
What is the most powerful controller of the adrenal gland?
ACTH
Means: secretion of cortisol (BIG 4 MINUS IMMUNE RESPONSE)
ACTH
What negative consequence is associated with high levels of ACTH?
Increase in cortisol (stress hormone)
What are symptoms of increased ACTH?
Pigmentation, moon face, buffalo hump
What is the site for endorphins?
POMC cells, adenohypophysis, placenta, spinal cord, hypothalamus (PPP)
Action: decrease pain, decrease reproduction
Endorphins
Means: decrease synthesis of substance P
Endorphins
What is the site for thyrotropin (TSH)?
Thyrotrope cells, adenohypophysis (PPP)
Action: stimulates development and maintains thyroid gland
Thyrotropin (TSH)
Means: BIG 4, increases memory
Thyrotropin (TSH)
What is the condition that results from lack of TSH?
Nonfunctioning thyroid gland
What is the site for follicle stimulating hormone (FSH)?
Gonadotrope, adenohypophysis (PPP)
Action: stimulates gonads to produce gametes
Follicle stimulating hormone (FSH)
Means in males: stimulate spermatozoa - seminiferous tubules (and increase memory)
FSH
Menas in females: stimulate ova - ovaries (and increase memory)
FSH
What are symptoms of issues with FSH?
Headaches and infertility
What is the site of activin?
Sertoli cells (male), granulosa of ovaries (female)
Action: stimulate secretion of FSH ONLY
Activin
Means: controls secretion of FSH
Activin and inhibin
What is the site for inhibin?
Sertoli cells (male), granulosa of ovaries (female)
Action: decrease secretion of FSH ONLY
Inhibin
What is the site for luteinizing hormone?
Theca interna
Action: stimulates the gonads, androgens, estrogen, progesterone
Luteinizing hormone
Means of luteinizing hormone?
BIG 4