Exam One: Antineoplastic Agents general drug classifications Flashcards

1
Q

Mechlorethamine

Cyclophosphamide

A

Alkylating and Related Agents

Nitrogen Mustards

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2
Q

Carmustine (BCNU)

Lomustine

A

Alkylating and Related Agents

Nitrosoureas

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3
Q

Busulfan

A

Alkylating and Related Agents

Alkyl Sulfonates

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4
Q

Dacarbazine

A

Alkylating and Related Agents

Triazenes

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5
Q

Procarbazine

A

Alkylating and Related Agents

Methylhydrazines

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6
Q

Cis-Platinum (Cisplatin)
Carboplatin
Oxaliplatin

A

Alkylating and Related Agents

Platinum Complexes

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7
Q

6-Mercaptopurine (6-MP)
6-Thioguanine (6-TG)
Fludarabine-5’- phosphate

A

Antimetabolites
Purine Analogs/Related Inhibitors
6-Thiopurines

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8
Q

Methotrexate

A

Antimetabolites

Folic Acid Analogs

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9
Q

Leucovorin

A

Antimetabolites

Folate Antagonist Rescue Agent

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10
Q

5-Fluorouracil (5-FU)
Cytarabine (AraC)
Gemcitabine

A

Antimetabolites

Pyrimidine Analogs

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11
Q

Vinblastine

Vincristine

A

Plant Alkaloids

Vinca Alkaloids

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12
Q

Paclitaxel

Abraxane

A

Plant Alkaloids

Taxanes

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13
Q

Topotecan

A

Plant Alkaloids

Camptothecins

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14
Q

Etoposide

A

Plant Alkaloids

Epipodophyllotoxins

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15
Q

Actinomycin D (Dactinomycin)

  • Anthracyclines
    - Adriamycin (Doxorubicin)
  • Bleomycin
A

Antitumor Antibiotics

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16
Q

Adrenocorticosteroids

-Prednisone

A

Hormonal Agents

17
Q

Long-acting Gonadotropin Releasing Hormone Agonists

-Leuprolide acetate

A

Hormonal Agents

18
Q

Antiestrogens

–Fulvestrant

A

Hormonal Agents

19
Q

Antiestrogens

-Fulvestrant

A

Hormonal Agents

20
Q

Aromatase inhibitors

  • Exemestane
  • Anastrozole
A

Hormonal Agents

21
Q

Antiandrogens

-Flutamide

A

Hormonal Agents

22
Q

Enzymes

A

Miscellaneous Antineoplastic Agents

L-asparaginase

23
Q

Substituted Ureas

A

Miscellaneous Antineoplastic Agents

Hydroxyurea

24
Q

Tretinoin (ATRA)

A

Miscellaneous Antineoplastic Agents

Differentiating Agents

25
Q

Imatinib mesylate

Gefitinib

A

Miscellaneous Antineoplastic Agents

Protein Tyrosine Kinase Inhibitors

26
Q

Bortezomib

A

Miscellaneous Antineoplastic Agents

Proteasome Inhibitors

27
Q

Trastuzumab
Rituximab
Cetuximab
Bevacizumab

A

Miscellaneous Antineoplastic Agents

Monoclonal Antibodies

28
Q

Interferon-alfa
Interleukin-2 (IL-2)
Granulocyte Colony-Stimulating Factor (G-CSF)
Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF

A

Miscellaneous Antineoplastic Agents

Biological Response Modifiers