Exam One: Antineoplastic Agents general drug classifications

Question 1

Mechlorethamine

Cyclophosphamide

Answer 1

Alkylating and Related Agents

Nitrogen Mustards

Question 2

Carmustine (BCNU)

Lomustine

Answer 2

Alkylating and Related Agents

Nitrosoureas

Question 3

Busulfan

Answer 3

Alkylating and Related Agents

Alkyl Sulfonates

Question 4

Dacarbazine

Answer 4

Alkylating and Related Agents

Triazenes

Question 5

Procarbazine

Answer 5

Alkylating and Related Agents

Methylhydrazines

Question 6

Cis-Platinum (Cisplatin)
Carboplatin
Oxaliplatin

Answer 6

Alkylating and Related Agents

Platinum Complexes

Question 7

6-Mercaptopurine (6-MP)
6-Thioguanine (6-TG)
Fludarabine-5’- phosphate

Answer 7

Antimetabolites
Purine Analogs/Related Inhibitors
6-Thiopurines

Question 8

Methotrexate

Answer 8

Antimetabolites

Folic Acid Analogs

Question 9

Leucovorin

Answer 9

Antimetabolites

Folate Antagonist Rescue Agent

Question 10

5-Fluorouracil (5-FU)
Cytarabine (AraC)
Gemcitabine

Answer 10

Antimetabolites

Pyrimidine Analogs

Question 11

Vinblastine

Vincristine

Answer 11

Plant Alkaloids

Vinca Alkaloids

Question 12

Paclitaxel

Abraxane

Answer 12

Plant Alkaloids

Taxanes

Question 13

Topotecan

Answer 13

Plant Alkaloids

Camptothecins

Question 14

Etoposide

Answer 14

Plant Alkaloids

Epipodophyllotoxins

Question 15

Actinomycin D (Dactinomycin)

• Anthracyclines
  - Adriamycin (Doxorubicin)
• Bleomycin

Answer 15

Antitumor Antibiotics

Question 16

Adrenocorticosteroids

-Prednisone

Answer 16

Hormonal Agents

Question 17

Long-acting Gonadotropin Releasing Hormone Agonists

-Leuprolide acetate

Answer 17

Hormonal Agents

Question 18

Antiestrogens

–Fulvestrant

Answer 18

Hormonal Agents

Question 19

Antiestrogens

-Fulvestrant

Answer 19

Hormonal Agents

Question 20

Aromatase inhibitors

• Exemestane
• Anastrozole

Answer 20

Hormonal Agents

Question 21

Antiandrogens

-Flutamide

Answer 21

Hormonal Agents

Question 22

Enzymes

Answer 22

Miscellaneous Antineoplastic Agents

L-asparaginase

Question 23

Substituted Ureas

Answer 23

Miscellaneous Antineoplastic Agents

Hydroxyurea

Question 24

Tretinoin (ATRA)

Answer 24

Miscellaneous Antineoplastic Agents

Differentiating Agents

Question 25

Imatinib mesylate | Gefitinib

Answer 25

Miscellaneous Antineoplastic Agents | Protein Tyrosine Kinase Inhibitors

Question 26

Bortezomib

Answer 26

Miscellaneous Antineoplastic Agents | Proteasome Inhibitors

Question 27

Trastuzumab Rituximab Cetuximab Bevacizumab

Answer 27

Miscellaneous Antineoplastic Agents | Monoclonal Antibodies

Question 28

Interferon-alfa Interleukin-2 (IL-2) Granulocyte Colony-Stimulating Factor (G-CSF) Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF

Answer 28

Miscellaneous Antineoplastic Agents | Biological Response Modifiers