Exam III - Blood & Hematopoiesis

Question 1

Which of the following is not a component of blood?

a. Blood plasma
b. Formed elements
c. Carbon dioxide
d. Platelets
e. White blood cells

Answer 1

C. Carbon Dioxide

Question 2

Which is NOT a major function of blood?

a. Transportation of nutrients
b. Regulation of blood pH
c. Protection against disease infection
d. Transportation of heat
e. Production of oxygen

Answer 2

e. Production of oxygen

Question 3

True or false: blood is a form of connective tissue.

Answer 3

TRUE TRUE!!

What what? Ohhhhhh yeaahhh!

Question 4

Whole blood makes up about _____% of body weight

Answer 4

Whole blood makes up about 5-10% of body weight

Question 5

What is the approximate lifespan of a canine red blood cell?

Answer 5

~110 days

Question 6

What is the approximate lifespan of an equine red blood cell?

Answer 6

~160 days

Question 7

What is the approximate lifespan of a feline red blood cell?

Answer 7

~70 days

Question 8

What is the approximate lifespan of a bovine red blood cell?

Answer 8

~145 days

Question 9

Identify the species that this blood smear was taken from?

Answer 9

Camelid species (elliptical or ovular RBC)

Question 10

Which species could this blood smear have been taken from?

Answer 10

Avian, Reptile, Amphibians or Fish

Nucleated RBC

Question 11

Which leukocytes can be categorized as granulocytes?

Answer 11

Neutrophils, eosinophils, and basophils

Question 12

Which leukocytes can be categorized as agranulocytes?

Answer 12

lymphocytes and monocytes

Question 13

What is the approximate diameter of a neutrophil?

Answer 13

~12 micrometers

Question 14

Identify the type of canine leukocyte indicated by ‘A’

Answer 14

Small lymphocyte

**has a large nucleus and a small amount of cytoplasm

Question 15

Identify the type of canine leukocyte indicated by ‘A’

Answer 15

Eosinophil

**note the bright pink granules in the cytoplasm

Question 16

What type of cell is indicated by the ‘A’ arrows?

Answer 16

neutrophils

Question 17

What type of cell is indicated by the ‘B’ arrows?

Answer 17

monocytes

Question 18

What is indicated by the ‘C’ arrows?

Answer 18

platelets

Question 19

What is pictured here?

Answer 19

Reactive Lymphocyte

**note the deeply stained or blue cytoplasm along with a perinuclear clear zone (halo)

Question 20

What is pictured here?

Answer 20

Large granular lymphocyte

**note the abundant cytoplasm and eosinophilic granules

Question 21

_________ are cytoplasmic fragments from megakaryocytes

Answer 21

platelets

Question 22

Identify the structures indicated by the arrows.

Answer 22

Platelets

Small, anucleate, discoid, cytoplasmic fragments of megakaryocytes. Contain granules; ~2-4 micrometers

Question 23

Which type of marrow produces all blood cells and stores iron?

Answer 23

Red marrow

Question 24

What is indicated by the large arrow in this H&E section of bone marrow? The small arrow?

Answer 24

large arrow - boney trabeculae

small arrow - hemopoietic cells and adipocytes

Question 25

In this H&E section of bone marrow, what is indicated by the white arrows?

Answer 25

sinusoidal capillaries

Question 26

_________ is the process in bone marrow where specialized cellular precursors develop into the highly differentiated cells of peripheral blood

Answer 26

Hematopoiesis

Question 27

What are the prenatal sites of hematopoeisis?

Answer 27

yolk sac, liver, spleen, lymph nodes, thymus, bone marrow

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Question 28

What are the postnatal sites of hematopoiesis?

Answer 28

Red Marrow:

Sternum, ribs, vertebrae, scapulae, skull, pelvis, proximal end of femur and humerus in older animals

Question 29

What is pictured in this image?

(Bone Marrow Aspirate, canine)

Answer 29

Osteoclast.

Multinucleated, specialized macrophage.

Nuclei are separate!

Question 30

What is pictured in this image?

(Bone Marrow Aspirate, canine)

Answer 30

Megakaryocyte.

Multilobulated nucleus divides by endomitosis.

One nucleus with different lobes