Exam III - Blood & Hematopoiesis Flashcards
Which of the following is not a component of blood?
a. Blood plasma
b. Formed elements
c. Carbon dioxide
d. Platelets
e. White blood cells
C. Carbon Dioxide
Which is NOT a major function of blood?
a. Transportation of nutrients
b. Regulation of blood pH
c. Protection against disease infection
d. Transportation of heat
e. Production of oxygen
e. Production of oxygen
True or false: blood is a form of connective tissue.
TRUE TRUE!!
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Whole blood makes up about _____% of body weight
Whole blood makes up about 5-10% of body weight
What is the approximate lifespan of a canine red blood cell?
~110 days
What is the approximate lifespan of an equine red blood cell?
~160 days
What is the approximate lifespan of a feline red blood cell?
~70 days
What is the approximate lifespan of a bovine red blood cell?
~145 days
Identify the species that this blood smear was taken from?
Camelid species (elliptical or ovular RBC)
Which species could this blood smear have been taken from?
Avian, Reptile, Amphibians or Fish
Nucleated RBC
Which leukocytes can be categorized as granulocytes?
Neutrophils, eosinophils, and basophils
Which leukocytes can be categorized as agranulocytes?
lymphocytes and monocytes
What is the approximate diameter of a neutrophil?
~12 micrometers
Identify the type of canine leukocyte indicated by ‘A’
Small lymphocyte
**has a large nucleus and a small amount of cytoplasm
Identify the type of canine leukocyte indicated by ‘A’
Eosinophil
**note the bright pink granules in the cytoplasm
What type of cell is indicated by the ‘A’ arrows?
neutrophils
What type of cell is indicated by the ‘B’ arrows?
monocytes
What is indicated by the ‘C’ arrows?
platelets
What is pictured here?
Reactive Lymphocyte
**note the deeply stained or blue cytoplasm along with a perinuclear clear zone (halo)
What is pictured here?
Large granular lymphocyte
**note the abundant cytoplasm and eosinophilic granules
_________ are cytoplasmic fragments from megakaryocytes
platelets
Identify the structures indicated by the arrows.
Platelets
Small, anucleate, discoid, cytoplasmic fragments of megakaryocytes. Contain granules; ~2-4 micrometers
Which type of marrow produces all blood cells and stores iron?
Red marrow
What is indicated by the large arrow in this H&E section of bone marrow? The small arrow?
large arrow - boney trabeculae
small arrow - hemopoietic cells and adipocytes
In this H&E section of bone marrow, what is indicated by the white arrows?
sinusoidal capillaries
_________ is the process in bone marrow where specialized cellular precursors develop into the highly differentiated cells of peripheral blood
Hematopoiesis
What are the prenatal sites of hematopoeisis?
yolk sac, liver, spleen, lymph nodes, thymus, bone marrow
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What are the postnatal sites of hematopoiesis?
Red Marrow:
Sternum, ribs, vertebrae, scapulae, skull, pelvis, proximal end of femur and humerus in older animals
What is pictured in this image?
(Bone Marrow Aspirate, canine)
Osteoclast.
Multinucleated, specialized macrophage.
Nuclei are separate!
What is pictured in this image?
(Bone Marrow Aspirate, canine)
Megakaryocyte.
Multilobulated nucleus divides by endomitosis.
One nucleus with different lobes
