EXAM I Review T/F Part2 Flashcards
LPS is a pyrogen
True
LPS is a endotoxin
True
LPS is a exotoxin
False
LPS is a toll-like receptor ligand
True
LPS is a common molecule is a gram-positive bacteria
False
A toxoid is a particularly potent toxin
False
Diapedesis is the same as extravasion
True
“LAD” stands for “Lateral Asymmetric Disjunction”
False
“PAMP” stands for “Pathogen Associated Molecular Pattern”
True
“PRR” stands for “Pathogen Recognition Receptor”
True
“TLR” stand for “Toll-like receptor”
True
TLRs are important PRRS
True
TLR ligands include LPS, flagellin, and unmethylated CpG DNA
True
TLR ligands include methylated CpG DNA, ds RNA, and Hsp60
False
Some TLRs detect endosomal ligands
True
TLRs only detect extracellular ligands
False
TLRs never hetrodimerize
False
TLRs never homodimerize
False
Adjuvant comes from the Latin word meaning “to share”
False
Freund’s complete adjuvant contains oil
True
Freund’s complete adjuvant contains killed Mycobacteria
True
Freund’s complete adjuvant contains alum
False
Freund’s complete adjuvant is used in many human vaccines
False
Precipitated or aggregated antigen is not immunogenic
False
Presence of TLR ligands makes immune responses weaker
False
Intravenous administration of antigen is maximally immunogenic
False
Oral administration of antigen can lead to tolerance
True
DNA is a good immunogen
False
Small Compounds such as caffeine are excellent immunogens
False
Polylysine is an excellent immunogen
False