EXAM I Review Immunoglobins Flashcards
Mediates Allergic Responses
IgE
Is found on the surface of Mast B cells
IgE
Is found primarily on the surface of B cells
IgD
Is found primarily in secretions
IgA
Is especially good at “opsonizing”
IgG
Is especially good at “fixing complement”
IgM
Has no known function
IgD
Crosses the placenta
IgG
is dimeric
IgA
is pentameric
IgM
Is present in Saliva and other secretions
IgA
Has the longest half-life
IgG
Has the shortest half-life
IgE
Is especially important in hemagglutination (transfusion) reactions
IgM
Can be bactericidal in the presence of lysozyme
IgA
Is co-expressed with IgD on the surface of B cells
IgM
Undergoes “transcytosis”
IgA
Binds the “poly Ig receptor”
IgA
May have a role in protecting against parasitic worms (helminthes)
IgE
Is especially useful for passive immunization
IgG
Is the best agglutinating antibody
IgM
Is the second best agglutinating antibody
IgA
Binds to Fc receptors on macrophages
IgG
Is the first antibody to appear in serum after antigenic exposure
IgM
Is an indicator of recent or acute infection of immunization
IgM
Has two subtypes
IgA
Has four subtypes
IgG
Is associated with the “secretory component”
IgA
Is, by concentration, the dominant antibody in serum
IgG
Antibody with the lowest concentration in serum
IgE
