Exam 5 Tips 11-13 Flashcards
What are the two major parts of the nervous system in humans?
-CNS & PNS
A neuron has 3 general parts: cell body, dendrite, and axon. What are the specific parts of each of those? Where are they located? What do they do?
- cell body: nucleus and organelles
- perikaryon: cytoplasm that contains organelles that provide energy & synthesize neurotransmitters (everything in cytoplasm)
- neurofilaments: located in the cytoskeleton, neurofibrils are bundles of neurofilaments that extend into dendrites and axons to provide internal support
- nissl bodies: clusters of RER and free ribosomes (makes proteins)
- dendrites: receives information
- dendritic spines: long processes on dendrite branches
- axons: carries information
- axon hillock: base of axon, connection point of cell body & axon
- axolemma: specialized plasma membrane that surrounds the axoplasm
- axoplasm- cytoplasm
- telodendria: extensions of main axon, end in synaptic terminals
What is a synapse? What is the difference between a pre and post-synaptic cell?
- specialized site where the neuron can communicate with other cells
- presynaptic: will always be a neuron
- postsynaptic: can be either to a muscle, gland, or another neuron
There are three types of synapses. What are they?
- neuron to neuron
- neuron to muscle
- neuron to gland
Why can’t CNS neurons repair themselves?
-they lack centrioles and therefore cannot divide to produce more cells
Neurons are classified on structure and function. What are the 4 structural classes? Know the basics about each one. What are the three functional classes? How are they different?
- anaxonic: without distinguishable axon, in the brain & special sense organs
- bipolar: # of times something is leaving cell body, rare but in special sense organs
- unipolar: continuous dendrite & axon that leave from 1 place, in sensory neurons of PNS
- multiplar: typical neuron, most common neuron in CNS, in motor neurons
- sensory: monitoring our senses, bringing in info
- interneurons: bridge neurons in between motor and sensory
- motor neruons: going out & doing the job
We have seen neuroglia before. How are they different between the CNS and the PNS?
- neuroglia of CNS
- ependymal cells: forms lining that is filled with cerebrospinal fluid
- microglia: small, clean neural tissue
- astrocytes: do many functions
- oligodendrocytes: produce myelin, think of as greasing the neuropathway
- neuroglia of PNS
- schwann cells: produce myelin sheath around axons
- satellite cells: surround neuron cell bodies in ganglia
Generally describe Wallerian degeneration.
- the repair of damaged nerves
- schwann cells come in and lay a pathway for new growing axon to follow, axon starts to repair itself and follows pathway, axon reconnects to other cell/synapse and schwann cells will form around new axon and/or myelinate it depending on what kind of cell it is