Exam 4 - endocrine Flashcards
what is function of exocrine?
secrets products onto free surface or into ducts ( sweat and oil glands)
What is function of endocrine?
Secretes products into extracellular space and moves into the blood stream
Major human endocrine glands found in brain?
- Hypothalamus
- Pineal Gland
- Pituitary gland
Major human endocrine glands found in neck?
- Thyroid gland
2. Parathyroid gland
Major human endocrine glands found in kidney?
- Adrenal gland
2. Pancreas
Major human endocrine glands found in reproductive system?
- Ovary
2. Testes
How do endocrine hormones and neurohormones function?
They fucntion as long-distance regulators of many physiological processes
What are the three types of hormonal control pathways?
- Simple endocrine pathway
- simple neurohromone pathway
- simple neuroendocrine pathway
What regulates many hormonal pathways involved in homeostasis?
Negative Feedback
How do we block a pathway?
- Enzyme inhibition
2. blocking gene expression
Three major classes of molecules functions hormones in vertebrates. what are they?
- proteins and peptides
- amines derived from amino acids
- steroids
Signaling by any of the three major classes of molecules involve three key events. what are they?
- Reception ( binding to the receptor)
- signal transduction ( series of chemical rxns)
- response ( chemical/hormone released )
Where can you find the receptors for most water-soluble hormones?
- They are found embedded in the plasma membrane, projecting outwards form the cell surface.
pathway of water soluble hormones?
- The hormones bind to a signal receptor protein on the surface of the target cell
- this interaction triggers events that leads to either a change in cytoplasmic function or a change in gene transcription in the nucleus.
Pathway of a lipid soluble hormone?
- The hormone binds to a transport protein to make it soluble when traveling across the blood
- it then PENETRATES the target cells plasma membrane and BINDS to an INTRACELLULAR signal receptor, either in the cytoplasm, or in the nucleus.