Exam 4 Flashcards
Hair and Turbinates
shell-shaped structures in nose and cilia in the upper and lower airways
Trap and remove foreign particles from the air
Mucosal lining
Upper and lower airways
Warms and humidifies air
Irritant receptors
Trigger a sneeze or cough reflex to remove foreign particles
Immune protections
Immune coating in the respiratory tract mucosa macrophages in the alveoli
Ventilation
The movement of air between the atmosphere are the respiratory portion of the lungs
Perfusion
The flow of blood through the lungs
Diffusion
The transfer of gases between the air-filled spaces in the lungs and the blood
Inspiration
Air is drawn into the lungs as the respiratory muscles expand the chest cavity
Expiration
Air moves out of the lungs as the chest muscles recoil and the chest cavity becomes smaller
Respiratory Control: Centers in the brain
Brainstem (neurons in pons and medulla)
Respiratory Control: Lung receptors
Located in the epithelium and smoot muscles of airways near alveolar-capillary junctions
Respiratory Control: Chemoreceptors
Critical sensors for alterations in blood chemistry (detects oxygen, carbon dioxide, and acid-base status)
Lung Capacity: Tidal Volume (TV)
Aprox. 500 mL at rest
Amount of air that moves into and out of the lungs during a normal breath
Lung Capacity: Inspiratory reserve volume (IRV)
Aprox. 3000 mL at rest
The amount of air that can be inhaled after a normal breath
Lung Capacity: Expiratory reserve volume (ERV)
Aprox. 1100 mL at rest
The amount of air that can be exhaled after a normal breath
Lung Capacity: Vital Capacity (VC)
Aprox. 4600 mL at rest
Equals the IRV plus the TV plus the ERV
The maximum amount of air that can be moved in and out of the lungs with forced inhalation and exhalation
Lung Capacity: Forced vital capacity (FVC)
The maximum amount of air that is exhaled from the lungs during a forced exhalation
Lung Capacity: Forced expiratory volume in 1 second (FEV1)
Max amount of air that can expire from the lungs in 1 second
Lung Capacity: Residual Volume (RV)
The air that remains in the lungs after forced respiration
Lung Capacity: Total lung capacity (TLC)
The total amount of air in the lungs when they are maximally expanded and is the sum of the VC and RV
Description of Pattern: Eupnea
The expected pattern of breathing is characterized by a rate between 10 and 20 breaths/min in adults, 500 and 800 mL in-depth, and a regular rhythm
Description of Pattern: Tachypnea
Rapid shallow breathing characterized by a rate of breathing above 24 breaths/min in adults
Description of Pattern: Apnea
Cessation of breathing for 10 seconds longer usually interspersed with another breathing
Description of Pattern: Hyperpnea
Increase in the rate and depth of breathing. Hyperpnea is responsive to PaO2/PaCO2 requirements; hyperventilation occurs in excess of what is needed to maintain PaCO2
Description of Pattern: Bradypnea
Slow breathing with regular depth and rate. Hypoventilation refers to decreased and inadequate ventilation
Description of Pattern: Cheyne-Strokes
A breathing pattern that alternates hyperpnea in a crescendo-decrescendo pattern and periods of apnea
Description of Pattern: Ataxic breathing
A breathing pattern of unpredictable irregularity. Can combine any or all breathing patterns
Description of Pattern: Obstructive breathing
Prolonged and incomplete expiration to overcome increased airways resistance and air trapping
Reason for Occurrence: Eupnea
Effective and responsive gas exchange
Reason for Occurrence: Tachypnea
The body needs to release excess carbon dioxide and respond by increasing the breathing rate. This is an expected response to fever fear or excersie can also occur with respiratory insufficiency pneumonia or injury to respiratory centers
Reason for Occurrence: Apnea
Can result from brain injury, premature birth or as an obstructive process during sleep
Reason for Occurrence: Hyperpnea
Excess carbon dioxide needs to be released. This can occur with extreme exertion, fear, or anxiety or with diabetes, ketoacidosis, aspirin overdose or brain injury. Hyperventilation blows off excessive CO2 causing a decreased level in the blood.
Reason for Occurrence: Bradypnea
During-induced depression of the respiratory centers increased intracranial pressure in a diabetic coma
Reason for Occurrence: Cheyne-Strokes
Increased intracranial pressure, bilateral damage to breathing areas in the cerebral hemisphere or diencephalon, during induced respiratory depression, heart failure, uremia
Reason for Occurrence: Ataxic breathing
Severe head trauma and damage to respiratory centers, brain abscess, heat stroke, spinal meningitis, and encephalitis.
Reason for Occurrence: Obstructive breathing
Chronic obstructive lung disease, asthma, chronic bronchitis
Diffusion
Oxygen and carbon dioxide are exchanged at alveolar capillary junctions
Partial pressure
The collision of oxygen and carbon dioxide creases pressure
Functions of Bronchial Smooth Muscles
The tone of the bronchial smooth muscles surrounding the airways determines the radius of the airway
Impaired Ventilation
A problem of blocking airflow in and out of the lungs
Impaired Diffusion
Restricted transfer of oxygen or carbon dioxide across the alveolar-capillary junction
Hypoxemia
Decreased oxygen in the arterial blood
This leads to a decrease in PaO2
Hypoxia
Oxygen deprivation in the cells
Hypercapnia
Increased carbon dioxide in the blood
Hypoxemia results from:
Inadequate O2 in the air
Disease of the respiratory system
Dysfunction of the neurological system
Alterations in circulatory function
Hypoxemia Mechanisms:
Hypoventilation
Impaired diffusion of gasses
Inadequate circulation of blood through the pulmonary capillaries
Mismatching of ventilation and perfusion
Hypercapnia
Too much carbon dioxide in the blood
Symptoms of respiratory distress and hypoxia: Early symptoms
Restlessness
Tachycardia
Tachypnea,
exertion dyspnea
Orthopnea
Tripod positioning
anxiety
difficulty speaking
poor judgment
confusion
disorientation
Symptoms of respiratory distress and hypoxia: Late Symptoms
Extreme restlessness to stupor
Severe dyspnea
Slowing of respiratory rate
Dradycardia
Cyanosis
Intercostal retraction
Cyanosis
Oxygen saturation <85% with bluish or purple discoloration of the skin
Asthma Pathophysiology
Intermittent or persistent airway obstruction due to:
Bronchial hyper-responsiveness
Chronic inflammation
Bronchoconstriction
Excess mucous production
Chronic Obstructive Pulmonary Disease (COPD) Types
Emphyseam-Enlargement of air spaces and destruction of lung tissue
Chronic Obstructive Bronchitis-Obstruction of small airways
Emphysema Pathophysiology
Irreversible enlargement of the air spaces beyond terminal bronchioles
Emphysema Treatment
Maintaining optimal lung function to allow the individual to perform the desired activities of daily life:
Smoking cessation
Pharmacologic therapy
Lung volume reduction or transplant
Chronic Bronchitis Pathophysiology
Persistent productive cough lasting greater than or equal to 3 months for greater than or equal to 2 years
Chronic Bronchitis Treatment
Smoking cessation
Pulmonary rehabilitation
Pharmacologic therapy
supplemental oxygen
Pneumonia Pathophysiology
Infectious process
Respiratory droplet spread
causes inflammation of the lungs
It occurs commonly in the bronchioles, interstitial lung tissue, and the alveoli.
Products of inflammation accumulate and cause consolidation.
Pneumonia Treatment
Restore optimal ventilation and diffusion
Identify pathogen and target with appropriate pharmacologic treatment
Supplement oxygen
ARDS Pathophysiology
Progression from lung injury to respiratory distress within 24-48 hr
Severe acute inflammation and pulmonary edema without evidence of fluid overload or impaired cardiac function
The mortality rate of 30%-40% from multisystem organ failure in those untreated
ARDS Treatment
Humidified O2
sedatives
opioids
neuromuscular blockers
sodium bicarbonate
IV fluids
vasopressors
Antimicrobial drugs
diuretics
correction of electrolyte acid-base imbalances
COVID 19
Corona group of viruses that cause respiratory from mild cold to severe depending on the type of coronavirus
Lifethreatening-Severe acute respiratory system corona virus(SARS-COV) Midle East respiratory syndrome (MERS-CoV) SARS-CoV 2=COVID 19
COVID 19 Treatment
Prevention with vaccines, masking, and social distancing