Exam #4 Flashcards
Who was Sir William Bowman?
surgeon/histologist who first described the function unit of the kidney (nephron) in 1842
What are the functions of the urinary system?
collects waste products, concentrates waste products, eliminates waste, and reabsorbs material the body can use
What materials can the urinary system reabsorb so the body can use it?
-minerals
-water
-proteins
-other
how much fluid is obtained in our kidneys?
about 100 gallons in 24 hours
What is the basic pathway through from the renal artery to the nephron?
renal artery->renal hilus->segmental arteries->interlobar arteries-> arcuate arteries ->cortical radiate arteries-> afferent arteriole->nephron
What is the basic pathway from the bowman’s capsule to the urethra?
nephron-> proximal convulated tube-> loop of henle->distal convulated tube->collecting ducts->renal pelvis-> ureter-> bladder-> urethra
What is another name for a glomerular capsule?
bowman’s capsule
What is the juxtaglomerular nephron?
the proximal convulated tube and the loop of henle occurs deeper within the medulla
what is the cortical nephron?
placed higher in the cortex and has a shorter loop of henle
What surrounds the nephron loop?
The vasa recta
What is the role of the vasa recta?
to recycle water, vitamins, and minerals
How much mitochondria is needed in the PCT and why?
large number of mitochondria and also display microvilli (more is needed for absorption)
How much mitochondria is needed for the DCT and why?
cuboidal cells don’t contain as much mitochondria
What happens when the blood enters the glomerular cap bed?
waste and blood separate
Where does gas exchange occur?
pertibular capillaries and vasa recta
Where is the juxtaglomerular cells located?
at the entrance of the afferent arteriole
Is pressure higher is the afferent or efferent arteriole?
efferent arteriole has higher bp than afferent
do the caps have high bp?
very high bp
What kind of cap is in the bowman’s caps and why?
fenestrated capillaries allows for plasma to leak out
What is the function of the podocyte?
wrap around segments of fenestrated caps structural support and helps caps endure high bp they face
What is the pressure is the glomerular cap bed?
60 mmHg
What is colloid osmotic pressure?
pressure that is a form of water pressure induced by proteins in the plasma that displaces water molecule
capsular pressure?
pressure expanded by bowman’s capsule pushing back the fluid in the capsule
Is there gas exchange in the bowman’s capsule?
NO GAS EXCHANGE
What is glycemia?
presence of glucose in the blood
Why is there glycemia in the blood?
glucose transport proteins can’t absorb all of the glucose in the blood
facilitated diffusion and passive transport is with or against the gradient?
high to low
does active transport require ATP?
yes, because it goes against the gradient
what do granular cells secrete?
renin
What are things being absorbed by urine?
-glucose
-amino acids
-protein
-vitamins
-lactate
-urea
-uric acid
What are tubular secretions?
urea, uric acid, and creatine
What is the pressure of a peritubular cap?
around 10mmHg
What does chronic hypertension cause glomerular caps to do?
causes them to rupture which leads to RBC
What is the trigone?
entry points for the ureters and exit point (urethra)
Where does most bladder cancer occur and why?
trigone because lots of carcinogen exposure so increasing fluids helps dilute urine
What is ammonia?
deamination of amino acids results in the production of amino acids
What is urea?
the liver converts some ammonia to urea
What is creatine?
formed during muscle usage
what is the micturition reflex?
has both involuntarily controlled and voluntarily controlled components.
what is aldosterone?
-produced in the adrenal cortex
-produces Na and water reabsorption
-maintains blood volume
-reduces urine input
What is angiotensin II?
-reduces water loss, stimulates thirst, and increases blood pressure
What is antidiuretic?
promotes water reabsorption, reduces urine volume
What does epinephrine and norepinephrine do?
induce renin secretion by loop and DCT