Exam 4 Flashcards
where is precordial stethoscope placed
4th intercostal space and LEFT sternal border
is Vt based on IDEAL body weight
yes (6-8ml/kg)
low BLOOD O2
hypoxEMIA
low TISSUE oxygen
hypoxia
oxygen consumption
VO2
oxygen delivery
DO2
(DO2 tissue is MORE important than DO2 lung)
Low inspired oxygen (FiO2)
Hypoventilation
V/Q mismatch leading to shunt
Diffusion limitations
HYPOXEMIC hypoxia
Not enough Hgb hypoxia
ANEMIC hypoxia
Decreased release of O2
AFFINITY hypoxia
Not enough cardiac output
CIRCULATORY hypoxia
Cell won’t accept the delivery of the O2
HISTIOCYSTIC/O2 utilization hypoxia
when are you more likely to illustrate cyanosis
with HIGH hgb
does an increase in CO2 cause decrease in O2
YES
If SpO2 is near 100% then increasing FiO2 will have ________ effect on DO2
little effect
what are the wavelengths for pulse ox
660nm
940nm
what cause false LOW pulse ox readings
Excessive motion
Blue nail polish
Anemia (low Hgb concentration)
SpO2 < 60%
Improper fitting probe
MetHgb similar to Hgb; if SaO2 (actual oxygen saturation) GREATER than > 85% then SpO2 will show low
what causes dramatically LOW pulse ox
IV methylene blue dye
what causes falsely HIGH pulse ox
Ambient fluorescent light
Carbon monoxide poisoning
MetHgb similar to Hgb; if SaO2 (actual oxygen saturation) LESS than < 85% then SpO2 will show high
what is most accurate spo2 location
cheek
decreased CO2
Hyperventilation: too much elimination
Hypotension
Decreased CO
R to L pulmonary shunt
Hypothyroidism
Hypothermia
Paralysis, motionless
examples of obstructive issues
COPD, bronchospasm, asthma, cystic fibrosis
looks like a “sharks fin”
what is the issue with capnography for non-intubated patients
no plateau phase, not accurate
what is the measurement for STATIC lung compliance
plateau pressure (end inhalation prior to exhalation)
ALWAYS lower than peak pressure
MORE accurate than dynamic compliance
STATIC lung compliance:
Indicates compliance ___________ resistance
Indicates compliance WITHOUT resistance
Measures lung compliance + airway resistance
DYNAMIC lung compliance
what is the measurement for DYNAMIC lung compliance
peak pressure
Pip – plateau pressure =
resistance
increased PiP withOUT plateau pressure increase?
issues with the tube, secretions, foreign body
increased inspiratory gas flow rate
Effort INdependent
Most objective measurement of airway resistance for medium airways
Most sensitive indicator of obstructive disease
Normal: 4-5L/sec
Forced Expiratory Flow (FEF) between 25% and 75% of exhaled breath
Spirometry measures lung _________, __________, and _______
lung volumes, capacities, and flows
o Helps identify airway resistance
o Normal: at least 80% of vital capacity
Forced Expiratory Volume over one second (FEV1)
o Declines with age
o Normal: at least 80%
Forced Expiratory Volume/Forced Vital Capacity (FVC)
Forced expiratory volume 40%
obstructive
forced expiratory volume 90%
restrictive
forced expiratory volume 80%
normal
difficulty getting air OUT of the lungs
obstructive
difficulty getting air INTO the lungs
restrictive
Enlarged TLC, RV, FRC
Reduced ERV
obstructive
FEV1/FVC ratio preserved
Reduced TLC, FRC, RV, FVC & FEV1
restrictive
loop looks like upside down ice cream cone*
NORMAL (FLOW volume loop)
smaller, normal FLOW volume loop shape
restrictive
- Shape is caved in which indicates expiratory obstruction
- Lung volumes are larger
- Flows are reduced
- FLATTER, LESS ROUND shape as air flow is impeded
obstructive
Analyzing shapes and steepness
Indicator of lung compliance (distensibility)
Yields info regarding leaks, lung over-inflation and obstruction
PRESSURE volume loops
pressure volume loop:
during mechanical/positive pressure ventilation
COUNTER-clockwise
pressure volume loop:
during spontaneous ventilation
CLOCKWISE
pressure volume loop:
Higher pressure moves loop farther ______
RIGHT
pressure volume loop:
Flatter slope = ______________ compliance
DECREASED compliance
pressure volume loop:
Steeper slope = _____________ compliance
INCREASED compliance
flow volume loop:
moves in ______________ direction
clockwise
2 examples of fixed obstruction
tumor, tracheal stenosis
Expiration and inspiration constant
fixed obstruction
inspiration: airway narrows
expiration: opens
(milkshake!)
EXTRAthoracic
inspiration: opens airway
expiration: narrows
INTRAthoracic
example of restrictive disease
pulmonary fibrosis
electrolytes:
hyperreflexia
hypotension after induction
ataxia
seizures
HYPERnatremia
electrolytes:
decreased reflexes
seizures
lethargy
HYPOnatremia
electrolytes:
too rapid a correction leads to demyelination of pontine neurons*
associated with 3% hypertonic saline
central pontine myelinolysis
electrolytes:
prolonged PR interval
peaked T wave
HYPERkalemia
electrolytes:
Avoid HYPOventilation (acidosis)
for every 10-mmHg change in EtCO2 the ___+ changes 0.5 mEq
potassium
hyperkalemia dont hypoventilate!
electrolytes:
high U waves
flattened or inverted T waves
low ST segment
digoxin toxicity
HYPOkalemia
electrolytes:
avoid HYPERventilation (alkalosis) with ________________
HYPOkalemia
electrolytes:
DECREASED reflexes
lethargy
confusion
(breast cancer + hyperparathyroidism)
HYPERcalcemia
electrolytes:
INCREASED reflexes
tetany, twitching, tingling lips and fingers
laryngospasm
HYPOcalcemia
electrolytes:
associated with alkalosis, hypoparathyroid
HYPOcalcemia
(avoid hyperventilation)
electrolytes:
relaxes muscles
HYPERmagnesia + HYPOmagnesia
use nerve stimulator always!
electrolytes:
lethargy
(preeclampsia)
HYPERmagnesium
electrolytes:
Poor GI absorption, dialysis, ETOH
HYPOmagnesium
drugs that cause HYPOkalemia
-beta adrenergic agonists
-catecholamines (epi, norepi)
-insulin
-loop diuretics
-thiazide diuretics
-aminoglycosides
-mineralcorticoids (aldosterone)
-AT II
drugs that cause HYPERkalemia
-NSAIDS
-Sch
-digoxin
-ACE inhibitors
-beta blockers
-potassium sparing diuretics
-AT II blockers
SV / (divided by) end diastolic volume
EF
(normal is 55% or greater)
normal SVO2
70-80%
calcium = ___________ potential
threshold
potassium = _____________ potential
resting
what impacts SVO2 (4)
o Oxygen consumption (VO2)
o Hemoglobin level (Hgb)
o Cardiac Output (CO)
o Arterial oxygen saturation (starting) (SaO2)
SVO2 varies ___________ with VO2 (oxygen consumption)
inversely!
as VO2 increases, SVO2 decreases
(all the others are directly related)
decreased SvO2
- Increased VO2 (fever, hyperthermia)
- Decreased Hgb (anemia, hemolysis)
- Decreased SaO2
- Decreased CO (ex: MI, CHF, hypovolemic states)
increased SvO2
- Decreased VO2 (cyanide toxicity, carbon monoxide poisoning, hypothermia, sepsis)
- Increased Hgb (volume depleted)
- Increased SaO2
- Increased CO (burns, inotropic drugs)
CBF = ____–____ ml/100 gm/min = ISOELECTRIC EEG (internal cell)
15-20 ml/100 gm/min
CBF < ____ ml/100 gm/min = ↓ cell integrity =
<10 = irreversible injury
CBF < ____ ml/100 gm/min = __________ of EEG
< 25 = slowing
Cerebral perfusion pressure < ___ torr
<50 CPP= changes in EEG
cerebral perfusion pressure < ___ torr
<25 CPP = irreversible damage
torr =
pressure (associated with CPP)
anesthesia= _______________ changes
anesthesia= symmetrical
ischemia= ________ and ______________ changes
focal and Asymmetric
Fast activity, alert, eyes open, concentrating, anxious or busy thinking
beta
Normal, resting, relaxed, awake adults
alpha
Slow activity, considered abnormal in awake adults; subcortical lesions and encephalopathy
Normal in young children
theta
slowest, subcortical lesions and encephalopathy, hydrocephalus
Normal in babies
delta
SLOWEST frequency and highest amplitude
delta
FASTEST frequency and lowest amplitude
beta
accentuate frequency, then decrease it
Barbiturates and Benzodiazepines
slow frequency, increase amplitude (delta)
opioids
both frequency and amplitude are attenuated (slowed)
inhalation anesthetics
flat line EEG associated with anesthesia
indicative of decreased metabolic oxygen demands and neuroprotective qualities
(good thing!)
isoelectric state
Conscious recall or remembering exact events of previous experiences
explicit memory
Movement and ability to respond to commands without specific conscious recall of events (“awareness without recall”)
implicit (unconscious) memory
Also known as “recall”
consciousness (explicit memory) under general anesthesia with subsequent RECALL of the experienced events
awareness
Paralysis of un-anesthetized patients occurring when patients are given NMBs prior to anesthesia (out of sequence, mislabeling)
awake paralysis
surgeries with the highest risk of recall?
trauma»_space;> cardiac surgery»_space; c-section
to be a part of anesthesia awareness registry, you must experience _________ recall during general anesthesia
explicit
true or false
NO signs are reliable indicators of “light” anesthesia
true
what are the drugs that can mask signs of awareness during surgery
- 1st: NMBs
- Blockage of physiological responses
o Amphetamines
o Beta blockers
o Calcium channel blockers - High levels of vitamin C
to have NO awareness during surgery:
volatile anesthetic at > ____ MAC
> .7
(.5-.7)
5 questions used to assess awareness event:
What was the last thing you remember before you went to sleep?
What is the first thing you remember after your operation?
Can you remember anything in between?
Can you remember if you had any dreams during your procedure?
What was the worst thing about your procedure?
Burst suppression: EEG _______ to random burst of electrical activity
EEG SLOWS to random burst of electrical activity
4 benefits of BIS monitoring
Reduction of PONV
Utilization of less drug to achieve a hypnotic state (save money)
Rapid emergence and recovery from general anesthesia (more efficient)
Improved quality of recovery, reduced PACU length of stay
when is BIS required*
TIVA (use of propofol)
when is BIS indicated
Hemodynamically sensitive patients (trauma, elderly, etc.)
ECT (monitoring of sub-clinical seizure activity)
TIVA (use of propofol)
BIS**
recall
> 70
BIS**
general anesthesia
40-60
BIS**
burst suppression
20
BIS**
flat line EEG (good neuro protection + reduced demand for oxygen)
0
true or false
Do NOT rely on just a single monitor to test awareness
true
what can alter BIS value (7)
Hypothermia
shivering
warming blankets
head trauma
patient positioning
unipolar cautery
ketamine + nitrous (can INCREASE BIS value)