Exam 4 Flashcards

1
Q

Ch 41- Animal Nutrition

Essential Nutrients

What do they do?
What do they Include?
Do they need specific nutrients among species?

A
  • Preassemble organic molecules
    ( nutshell: we don’t synthesize them)
  • Amino Acids, Fatty acids, Vitamins, Minerals
  • Yes, specific nutrients vary among species
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2
Q

Animal Nutrition

Essential Nutrients [AA]

How many Amino Acids do we require?
What do most enzymes do?

What are remaining energy called & where is required?

A

Require 20 AA
- Most enzymes synthesize half of AA

Remaining energy is called essential AA
- Must be obtained from food in prefabricated forms

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3
Q

Animal Nutrition

Essential Nutrients [AA]

What food provide “Complete” ( provide all AA) ?

A
  • Meat
  • Eggs
  • Cheese

[ animal products ]

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4
Q

Animal Nutrition

Essential Nutrients [AA]

What food provide “Incomplete”?

A

Plant products

If taken, you have to consume wider variety

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5
Q

Animal Nutrition

Essential Nutrients [ Fatty Acids ]

What do fatty acids do?

Difference from animals?

A

Fatty acids => synthesize cellular components

Animals can synthesize but lack enzymes to form double bonds found in certain required fatty acids

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6
Q

Animal Nutrition

Essential Nutrients [Fatty Acids]

What is the name of the essential fatty acid for mammals and where can it be obtained?

A

Linoleic Acid

Can be obtained from:
- Seeds
- Grains
- Vegetables

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7
Q

Animal Nutrition

Essential Nutrients [Vitamins]

Do organic molecules require the diet to be in very small amounts?

A

Yes

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8
Q

Animal Nutrition

Essential Nutrients [Vitamins]

Name Diverse Functions & Where Found:

  • B2 (Riboflavin)
  • B7 (Biotin)
    -B9 (Folic Acid)
  • A (Retinol)
  • D
A
  • B2 (Riboflavin)
    => components of coenzyme FAD (e- carrier in cellular respiration pathway)
    => Diary/ Meat
  • B7 (Biotin)
    => Coenzyme in synthesis of fat, glycogen, & AA
    => Legumes
  • B9 (Folic Acid)
    => Coenzyme in Nucleic Acid & AA Metabolism ( break down to small components) [ build new things ]
    => Veg, oranges, nuts
  • A (Retinol)
    => component of visual pigments; maintenance of epithelial cells
    => Dark, leafy greens
  • D
    => Absorption of calcium and phosphorus
    => Egg Yolks
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9
Q

Animal Nutrition

Essential Nutrients [Minerals]

Are they inorganic or organic?

Are they required in small amounts?

A

Minerals are inorganic that they are required in small amounts

Ex. Iron & Sulfur

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10
Q

Animal Nutrition

Essential Nutrients [Minerals]

Diverse Functions in Animal Physiology
- Calcium (Ca)
- Potassium (K)
- Magnesium (Mg)
- Iron (Fe)
- Iodine (I)

A
  • Calcium (Ca)
    => Bone and tooth formation
    => Blood clotting
    => Nerve and Muscle Function
  • Potassium (K)
    => Acid Base Balance
    => Water Balance
    => Nerve Function
  • Magnesium (Mg)
    => ATP bioenergetics
  • Iron (Fe)
    => Component of hemoglobin and of electron carriers
  • Iodine (I)
    => component of thyroid hormones
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11
Q

Animal Nutrition

Essential Nutrients [ Diseases ]

Iodine Deficiencies can lead to ________?

Excess salt can lead to _________?

A
  • Lead to Goiter ( swelling of thyroid gland)
  • Can lead to high blood pressures
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12
Q

Animal Nutrition
Regulation of Digestion

Are Digestive Systems continually active?

A
  • Digestive systems are not continually active
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13
Q

Animal Nutrition
Regulation of Digestion

What are def: ?

Enteric Division?

Endocrine System?

A

Enteric Division:
=> Nervous system that regulates churning, release of gastric juices, and peristalsis

Endocrine System:
=> Hormones released by stomach and duodenum ensure digestive secretions are present only when needed

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14
Q

Animal Nutrition
Food Processing

What are the 4 steps of Food Processing?

A
  • Ingestion
  • Digestion
  • Absorption
  • Elimination
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15
Q

Animal Nutrition
Food Processing

Def of Ingestion

A

Act of eating or feeding

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16
Q

Animal Nutrition
Food Processing

Def of Digestion

2 Types of Digestion & Functions

A

Food is broken down into molecules small enough for body to absorb

  • Mechanical Digestion: Mouth (physically chew )
  • Chemical Digestion: Hydrolysis (enzymes coming in & break cmplx molec dwon to small molec
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17
Q

Animal Nutrition
Food Processing

Def of Absorption

A

Cells take up small molecules

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18
Q

Animal Nutrition
Food Processing

Def of Elimination

A

Undigested materials pass out of the digestive system

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19
Q

Animal Nutrition
Organs of Mammal Digestive System

What are accessory glands, what do they do, and which are they?

A
  • Secrete digestive juices thru ducts into canal
  • They consist
    => 3 pairs of salivary glands
    => Pancreas
    =>Liver
    =>Gallbladder
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20
Q

Animal Nutrition
Organs of Mammal Digestive System

What contraction of ring- like muscles help push food thru alimentary canal?

A

Peristalsis ( Esophagus)

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21
Q

Animal Nutrition
Organs of Mammal Digestive System

What regulate passage of materials b/w compartments & is muscular layer forms ringlike valves

A

Sphincters

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22
Q

Animal Nutrition
Organs of Mammal Digestive System

1st Step in digestion?

A
  • Oral Cavity (Ingestion)
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23
Q

Animal Nutrition
Organs of Mammal Digestive System

What does 1st step in digestion do?
Do any other glands help?

A
  • Mechanical digestion by teeth
  • Salivary Glands (Access gland) deliver saliva automatically
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24
Q

Animal Nutrition
Organs of Mammal Digestive System

Enzymes (-ase) secreted in oral cavity

A
  • Amylase = hydrolyzes starch & glycogen into smaller polysaccharides & maltose
  • Mucus = protects oral cavity, mixture of water, salts, cells and slippery glycoproteins (mucins)
    = Lubricates food, easier swallowing
  • Buffers = prevent tooth decay by neutralizing acid
  • Antimicrobial agents = protect against bacteria
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24
Q

Animal Nutrition
Organs of Mammal Digestive System

Function of Oral Cavity, Pharynx, & Esophagus

Tongue using _____ to manipulate mixture of food and saliva into a ball.

2 passageways in pharynx?

What does Epiglottis do?

A
  • Bolus
  • Trachea & Esophagus
  • Epiglottis prevents food from entering the trachea
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25
Q

Animal Nutrition
Organs of Mammal Digestive System

Stomach
What does it do?
What does it secrete and forms what?
Involuntary or voluntary muscle?

A
  • Stores food and begins digestion of proteins
  • Elastic wall w/ multiple folds
  • Secretes digestive fluid called gastric juice
    => mixes food via churning action forming chyme
  • involuntary (smooth muscle)
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26
Q

Animal Nutrition
Organs of Mammal Digestive System

Stomach
What does Gastric Juices contain?

A
  • HCL (Hydrochloric Acid): disrupts extracellular matrix that bind cells together in meat and plant material
  • Pepsin: (protease) breaks proteins into smaller polypeptides
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27
Q

Animal Nutrition
Organs of Mammal Digestive System

Why don’t HCL and pepsin eat thru lining of stomach?

A
  • Mucus prevents self- digestion
  • new layer of epithelial cells added every 3 days
  • Damaged areas result in Gastric Ulcers
  • Acid Reflux is backflow of chyme (throwing up)
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28
Q

Animal Nutrition
Organs of Mammal Digestive System

Accessory Organs

What do they do? What do they contain?
- Pancreas
- Liver

A
  • Pancreas
    = Produces alkaline soln rich in bicarbonate and several enzymes (trypsin & chymotrypsin)
    = Bicarbonate neutralizes acidity of chyme and acts a buffer
  • Liver
    = Bile aids in emulsification (large droplets to small lead to absorption & process to body) of fats and other lipids
    =STORES AND CONCENTRATED in gallbladder
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29
Q

Animal Nutrition
Organs of Mammal Digestive System

Small Intestine

What occurs most in Small Intestine?
What does it do?

A

Most enzymatic hydrolysis of macromolecules

  • chyme enters duodenum, mixes w/ digestive juices
  • Site of MOST Digestion
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30
Q

Animal Nutrition
Organs of Mammal Digestive System

Small Intestine Absorption

Where does it occur?
What helps contribute absorption?

A

Occurs in Jejunum (2nd smi) and Ileum (3rd smi)

  • Villi (fingerlike projecting lining intestine)
  • Microvilli (cover surface ) (increase surface area)
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31
Q

Animal Nutrition
Organs of Mammal Digestive System

Distribution of Nutrients

What do they do & functions

A

Capillaries and veins carry nutrient-rich blood away from villi and join with hepatic portal vein (leading to liver)
- blood travels to heart and other organs & tissues)

Function:
- Liver regulates distribution of nutrients to rest of body
- Allows liver to remove toxic substances
- Store energy rich molecules
- Storage spot for mineral

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32
Q

Animal Nutrition
Organs of Mammal Digestive System

Large Intestine

What do they do & Function?

A

Colon lead to rectum & anus (reabsorption of water )

  • Cecum
    = important for fermenting ingested material (esp animals that eat primarily plant tissue)
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33
Q

Animal Nutrition
Organs of Mammal Digestive System

Def of Diarrhea & Constipation

A

Diarrhea :
lining becomes irritated and LESS WATER than normal is reabsorbed (cannot absorb water)

Constipation :
Feces move along colon too SLOWLY and comes compacted (TOO MUCH WATER ABSORB)

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34
Q

Animal Nutrition
Digestive compartments

Intracellular Digestion

A

Occurs in lysosomes
Unicellular organism (sponges, amoeba)

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35
Q

Animal Nutrition
Digestive compartments

Extracellular Digestion

A

Breakdown of food that are continuous w/ outside of animal’s body

mouth to anus

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36
Q

Animal Nutrition
Digestive compartments

Simple body plans (def)

Gastrovascular Cavity

A

Simple BP: digestive compartment w/ single opening

Gastro cavity: functions in digestion and distribution of nutrients thruout body (hydras & flatworms)

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37
Q

Animal Nutrition
Digestive compartments

complete digestive tract ( 2 opening)

Another name called?
Function?

A

Alimentary Canal

  • Food moves in single direction in stepwise fashion
  • organized into specialized compartments w/ specific function
  • Allows animals to ingest food while earlier meals still being digested
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38
Q

Ch 42: Circulation and Gas Exchange

Open vs Closed Circulatory Systems

A

Open Circulatory System
= Circulating Fluid: hemolymph & interstitial fluid that bathes body cells

Closed Circulatory System
= Blood confined to vessels and distinct from interstitial fluid

39
Q

Ch 42: Circulation and Gas Exchange

Structure & Function of 3 vessel Types:

  • Arteries
  • Veins
  • Capillaries
A

Arteries (thick walls) (high hydrostatic pressure)
> Carry blood AWAY from heart
> w/in organs - branch into arterioles - later branch to capillaries

Veins (Drain tissue)
> Carry blood back TO the heart
> Connect to Venules that collect fluid from capillaries

Capillaries (Thin/Leaky)
> Microscopic vessels w/ very thin, porous walls
> networks are called capillary beds
> ONLY VESSEL WHERE EXCHANGE OCCURS

40
Q

Ch 42: Circulation and Gas Exchange

Circulation of blood through heart:
Compare single vs double circulation

A

Single Circulation : Bony fishes, rays, sharks
> two chambered hearts (atrium and ventricle)
> Act of swimming = aid in circulation

Double Circulation : amphibians, reptiles, mammals
> Two circuits
- Pulmonary circuit (right side)
- Systemic circuit (left side)

41
Q

Ch 42: Circulation and Gas Exchange

Circulation of blood through heart:
Compare Circulation in Mammals, fish, & Amphibian

A

Amphibian: 3 chambers : Pulmocutaneous Circuit

Mammal : 4 chambers : Pulmonary Circuit

Fish: single Circulation : Gill capillaries :

42
Q

Ch 42: Circulation and Gas Exchange

Components of Blood

Plasma: Main function

A

water- 90%
Function: solvent

ion
Function: pH buffering

Plasma Proteins; immunoglobulin (antibodies)
Function: Defense
Apoliproteins: Lipid Transport

43
Q

Ch 42: Circulation and Gas Exchange

components of Blood

Erythrocytes (red blood cells)
Function?
Lack?
Contain?

A
  • Function: transport O2
  • lack nuclei and mitocondria (generate ATP by anaerobic metabolism)
  • Contain hemoglobin (iron containing protein that binds O2)

Have 4 subunits
2 alpha subunits & 2 Beta subunits

44
Q

Ch 42: Circulation and Gas Exchange

components of Blood

Leukocytes (fight infection)
Function?

A

Function: Defense and Immunity; Fight injection

some phagocytic

45
Q

Ch 42: Circulation and Gas Exchange

components of blood

Platelets (bone marrow/ blood clotting)
Contain?
Function?
What do they need?

A

Contain no nuclei
They are pinched of cytoplasmic fragments of specialized bone marrow

Function: blood clotting

Need: plasma, Enzymatic cascade, prothrombin, thrombin, fibrinogen, fibrin

Pos= high thrombin

46
Q

Ch 42: Circulation and Gas Exchange

Structure and Function of Heart

Chambers - atria and ventricles

A

Atria: Thin walled and serve as collection chambers

Ventricles: Thick walled and contract more forcefully

47
Q

Ch 42: Circulation and Gas Exchange

Structure and Function of Heart

Valves (4)

A

Function: prevent backflow
Made of connective tissue

Atrioventricular (AV) Valve- b/w R atrium & R ventricle

Semilunar Valve: 2 exits of heart (pulmonic & aortic)
Pulmonary artery: leaves R ventricle
Aortic: Leaves L Ventricle

48
Q

Ch 42: Circulation and Gas Exchange

Structure and Function of Heart

Nerves that regulate heart rate

Sympathetic Division: acts accelerator

Parasympathetic Division: acts as brakes

A

Sinoatrial (SA) node: sets rate & timing which all cardiac muscles cells contract

Atrioventricular (AV) node: signals travel to relay point (b/w atria)

Bundle Branches: pass signals to heart apex

Signals spread thruout ventricles (Purkinje fibers)

49
Q

Ch 42: Circulation and Gas Exchange

Characteristics of respiratory surfaces

a. Understand structure & function of respiratory surfaces discussed in diff animal groups
b. Where does gas exchange occur in each system

CUTANEOUS RESPIRATION

A

Earthworms and some amphibians

Respiration across skin
- Dense network of capillaries below skin facilitate the exchange of gases

Evolutionary soln?
Modifications that increase surface area

50
Q

Ch 42: Circulation and Gas Exchange

Characteristics of respiratory surfaces

a. Understand structure & function of respiratory surfaces discussed in diff animal groups
b. Where does gas exchange occur in each system

GILLS IN AQUATIC ANIMALS

A
  • Total surface area much greater than rest of body’s surface
  • VENTILATION: movement of water over gills
  • Mechanisms of VENTILATION
    = Walking (ventilation; attach to gills)
    = Swimming ( water to actively flow over gills)

Bony fishes = operculum (protect/ ventilate)

51
Q

Ch 42: Circulation and Gas Exchange

Characteristics of respiratory surfaces

a. Understand structure & function of respiratory surfaces discussed in diff animal groups
b. Where does gas exchange occur in each system

COUNTERCURRENT EXCHANGE

A
  • Exchange b/w two fluid flowing in opp directions
  • blood flows in opp direction to water passing over gills
52
Q

Ch 42: Circulation and Gas Exchange

Characteristics of respiratory surfaces

a. Understand structure & function of respiratory surfaces discussed in diff animal groups
b. Where does gas exchange occur in each system

TRACHEAL SYSTEM IN INSECTS

A

INSECTS - open circulatory system

TRACHEAL SYSTEM: terrestrial animals

  • Functions w/o circulatory system
  • TRACHEAE= network of air tubes that branch throughout the body
53
Q

Ch 42: Circulation and Gas Exchange

Characteristics of respiratory surfaces

a. Understand structure & function of respiratory surfaces discussed in diff animal groups
b. Where does gas exchange occur in each system

LUNGS

A

SPIDERS & LAND SNAILS, VERTEBRATES

Infolding, subdivided into numerous pockets

not in direct contact w/ parts of body, must be bridged by circulatory system

54
Q

Ch 42: Circulation and Gas Exchange

Pathway that air moves during inhalation & exhalation in mammals
HOW IS THIS ACCOMPLISHED?

neg pressure breathing: air pulled into lungs
Diaphragm: sheet of skeletal muscle

A

Air entering nostrils
- filter by hairs, warmed, humidified, sampled for odors

Air flow: pharynx, larynx, trachea

Gas exchange in alveoli

55
Q

Ch 42: Circulation and Gas Exchange

Pathway that air moves during inhalation & exhalation in mammals

What controls respiratory rate in humans?

A

Involuntary Mechanisms:
= Ensure gas exchange is coordinated w/ blood circulation & metabolic demand

Breathing control center is located in MEDULLA OBLONGATA
= Neg feedback mechanism prevent lungs from overexpanding

56
Q

Ch 44: Osmoregulation & Excretion

Osmoregulation
a. Unit of measurement of solute concentration

A

Osmoregulation: process by which animals control solute conc and balance water gain and loss

Diffusion of water from area of HIGH FREE WATER CONC to AREA OF LOWER FREE CONC: OSMOSIS

Unit of measurement of solute conc: OSMOLARITY (# of moles per solute per L of soln)

57
Q

Ch 44: Osmoregulation & Excretion

Osmoregulation
a. Unit of measurement of solute concentration
i. Meaning of hyperosmotic, hypoosmotic, isosmotic

A

Hypoosmotic: LOW solute conc, HIGH free water conc
= discharge water

Hyperosmotic: HIGH SOLUTE CONC, LOW free water conc
= take water from envir

Isosmotic: equal, no net movement of water

58
Q

Ch 44: Osmoregulation & Excretion

Osmoconformers vs Osmoregulators

A

Osmoconformer: animals isosmotic w/ its surroundings
> live in water w/ stable composition
> all marine animals
> no tendency to gain or lose water

Osmoregulators: animals controls internal osmolarity independent of that external environ (eg. salmon)
> freshwater and terrestrial habitats; some can move b/w fr water and marine environ
> must discharge or take on water accordingly

59
Q

Ch 44: Osmoregulation & Excretion

Osmoregulators

in fishes (marine and freshwater)

A

Osmoregulation in Marine fish:
> EXCRETION of salt ions from gills
> EXCRETION of salt ions and small amount of water in scanty URINE from kidneys

Osmoregulation in Freshwater fish:
> UPTAKE salt ions by gills
> EXCRETION of salt ions and large amounts of water in dilute urine from kidneys

60
Q

Ch 44: Osmoregulation & Excretion

Adaptation that reduce water loss in terrestrial animals

Structural & Behavioral

A

Structural adaptions:
> Waxy cuticle, shells of land snails, exoskeleton, keratinized skin cells

Behavioral adaptions:
> nocturnal behavior in deserts

61
Q

Ch 44: Osmoregulation & Excretion

Excretion

A

Excretion
process that rids body of nitrogenous metabolites and other metabolic wastes
(Breakdown of proteins and metabolic acids)

62
Q

Ch 44: Osmoregulation & Excretion

Excretion
Types of nitrogenous waste produced by animals

Pros and cons of each

A
  • Ammonia (NH3)
    > Most aquatic animals, most bony fishes
    > Pros: takes very little energy
    > Cons: Very toxic
  • Urea
    > Mammals, most amphibians, sharks, some bony fishes
    > Pros: Low toxicity
    > Cons: Requires more energy (high energy cost)
  • Uric Acid
    > Many reptiles (include birds), insects, land snails
    > Pros: Nontoxic
    > Cons: Not dissolve readily in water, semisolid paste (conserve most water)
    > Most energically expensive but conserves most water
63
Q

Ch 44: Osmoregulation & Excretion

Excretion
Process of excretion ( 4 steps )

A
  1. Filtration
  2. Reabsorption
  3. Secretion
  4. Excretion
64
Q

Ch 44: Osmoregulation & Excretion

Excretion
Organs involved

A

Excretory and osmoregulatory function/ organs

Kidney, Ureter, Urinary Bladder, Urethra (male: Large) (female: small), renal cortex, renal medulla

65
Q

Ch 44: Osmoregulation & Excretion

Excretion
Structure and Function of nephrons

A

Nephrons: functional units of kidneys

Cortical nephrons: reach a short distance into the medulla

Juxtamedullary nephrons: extend deep into medulla

*Key component to water conservation
* Essential for production of urine that is HYPEROSMOTIC (high solute conc) to body fluids

66
Q

Ch 44: Osmoregulation & Excretion

Excretion
Structure and Function of Nephrons
1st step filtration

A
  • Glomerulus: single long tubule and ball of capillaries
  • Bowman’s Capsule: surrounds glomerulus
    > FILTRATE forms when blood pressure forces fluid from blood in glomerulus into lumen of bowman’s capsule
    > Permeable to water and small solutes, NOT blood cells or large plasma proteins
67
Q

Ch 44: Osmoregulation & Excretion

Excretion
Structure and Function of Nephrons
2nd step reabsorption

A

Three regions:
- Proximal Tubule: near point of attachment (closest to glomerulus & bowman’s capsule)
- Loop of Henle
- Distal Tubule: far from point of attachment (connects to collecting duct)

  • Collecting Duct: receives and processed filtrate and delivers it to renal pelvis
68
Q

Ch 44: Osmoregulation & Excretion

Excretion
Structure and Function of Nephrons
3rd step

A

Proximal Tubules:
> reabsorption of water, ions, and nutrients
> reabsorbs 90% of bicarbonate

Descending limb of loop of Henle
> reabsorption of water continues
> AQUAPORIN: proteins make transport epithelium freely permeable to water

69
Q

Ch 44: Osmoregulation & Excretion

Excretion
Structure and Function of Nephrons
4th step

A

Ascending limb of loop of Henle
> no water channels, NaCl moves into interstitial fluid
> filtrate becomes more dilute

Distal Tubule
> Regulates K+ and NaCl conc of body fluids
> controlled secretion of H+ and reabsorption of bicarbonate

70
Q

Ch 44: Osmoregulation & Excretion

Excretion
Structure and Function of Nephrons
5th step

A

Collecting Duct
> Final processing forms urine as filtrate travels to renal pelvis

71
Q

Ch 46. Reproduction

Sexual vs Asexual Reproduction

A

Sexual Reproduction:
- fusion of haploid gametes to form a diploid cell (zygote)
- Use Egg and Sperm
Pros: increase variation w/in population
Cons: find mate for survival & contribute offspring

Asexual reproduction
- New offspring generate w/o fusion of egg and sperm
- relies entirely on mitotic cell division
- uncommon in animals

72
Q

Ch 46. Reproduction

Sexual vs Asexual Reproduction
Structure and Function of male reproductive organs

A

Testes - male gonads
> produce sperm in highly coiled SEMINFEROUS TUBULES
> scrotum: temp maintained

Ducts:
- seminiferous tubules to epididymis
- during Ejaculation, sperm go through muscular VAS DEFERENS
> Extends around bladder and joins Ejaculatory duct
> Open to urethra

Penis: contains urethra and three cylinders of spongy erectile tissue

Accessory Glands
- Seminal vesicles: produce fluid that is thick and alkaline
> contains mucus fructose, coagulating enzyme, prostaglandins

  • Prostate Gland: secretes a thin and milky fluid directly to urethra
    > contains anticoagulant enzymes and citrate
  • Bulbourethral Glands: pair of small gland along urethra below the prostate
    > secrete mucus to neutralize any acidic urine remaining in the urethra
73
Q

Ch 46. Reproduction

Sexual vs Asexual Reproduction
Structure and Function of female reproductive organs

A

Ovaries: flank the uterus and held by ligaments
> outer layer packed with FOLLICLES
– each contains an oocyte surrounded by support cells

Oviduct: extends uterus toward funnel-like opening at each ovary
> OVULATION: cilia on epithelial lining of oviduct help collect egg by drawing fluid from body cavity into oviduct

Uterus: Muscular organ that expand during pregnancy
- ENDOMETRIUM: inner lining
- CERVIX : opening to vagina

Vagina: muscular but elastic
-opens to outside of vulva (external female genitalia)
- LABIA MAJORA: enclose that protect the vulva
- LABIA MINORA: border vaginal opening and opening of urethra

Clitoris: erectile tissue that supporting a rounded glans covered by small hood of skin

74
Q

Ch 46. Reproduction

Sexual vs Asexual Reproduction
Male: Spermatogenesis

A
75
Q

Ch 46. Reproduction

Sexual vs Asexual Reproduction
Female: Oogenesis

A
76
Q

Motor Mechanics

Know def of bold terms

THICK and THIN FILAMENTS
ACTIN
MYOSIN
CHEMICAL ENERGY
CREATINE PHOSPHATE
GLYCOGEN
TETANUS
OXIDATIVE FIBERS
GLYCOYTIC FIBERS
FAST FIBERS
SLOW FIBERS

A

Thick and Thin Filaments (striations): muscle cell contraction relies on interaction b/w protein structures

Actin: major component in globular protein in thin filaments (2 strands coil around each other)

Myosin: Staggered arrays in thick filaments (aid in muscle contraction)

Chemical energy: Require ATP, product of filament movement, muscle extension only passively

Creatine phosphate: Transfers phosphate group to ADP to synthesize ATP; resting supply can sustain contraction for ~ 15 sec

Glycogen: Restores ATP when broken down to glucose, metabolized by aerobic respiration during light or moderate muscle activity
> HIGHLY EFFICIENT process that yield enough power to sustain contraction for nearly an hour

Tetanus: rate so high that muscle fiber cannot relax, twitches fuse into one smooth, sustained contraction

Oxidative Fibers: rely mostly on aerobic respiration, specialized to make steady energy supply (many mitochondria), large amount of oxygen- storing myoglobin

Glycolytic Fibers: large diameter and less myoglobin, glycolysis primary source of ATP, fatigue more readily

Fast Fibers: brief, rapid, powerful contractions
> can be oxidative or glycolytic, eyes and hands are exclusively fast twitch

Slow Fibers: less sarcoplasmic reticulum and pumps Ca 2+ slowly, muscle twitch last around 5x
> running, walking, swimming, riding bicycles

77
Q

Motor Mechanics

Muscle Anatomy
components of Muscle fibers

A

Thin: ACTIN: two strands of actin coil around each other
> Major component of globular protein

Thick: MYOSIN: staggered arrays of molecules

78
Q

Motor Mechanics
Muscle Anatomy

Contractile unit of Muscles

A

Sarcomere: muscle that shorten the extraction

Contracting muscle SHORTENS but filaments STAY SAME LENGTH

Require ATP and phosphate group for myosin energy to move the actin

79
Q

Motor Mechanics

Muscle anatomy
Levels of organization

A

Microscopic level (sarcomere and myofibrils), Cell level (myoblasts & myofibers), Tissue levels (neuromuscular junctions) , Organ level (major skeletal muscles)

80
Q

Motor Mechanics

Control of Muscle Contraction
Know step by step

A
  • Motor neurons trigger the release of Ca 2+ into cytosol of muscle cells (regulation of Ca 2+ is a multistep process)
  • Release of neuron transmitter (ACh) Acetylocholine
  • An action potential @ synaptic terminal of a motor neuron release acetylcholine (ACh)
    > Binds to receptors on muscle fiber leading to depolarization
81
Q

Motor Mechanics

Control of Muscle Contraction
How is it regulated?

A

Tropomyosin= regulatory protein
Troponin complex= actin strands of thin filaments

At rest tropomyosin covers the myosin-binding sites

When Ca 2+ accumulates in cytosol, it binds in troponin complex
> shifts position exposing the myosin-binding sites

Increase Ca 2+ => Contraction
Decrease Ca 2+ => Extension/ Relaxation

82
Q

Motor Mechanics

Types of Skeletal Muscle fibers

Dark meat = oxidative fibers
Light meat = glycolytic fibers

A

Oxidative Fibers:
- rely on AEROBIC respiration
- specialized to make steady energy supply
- rich blood supply
- large amount to oxygen-storing MYOGLOBIN

Glycolytic Fibers:
- LARGE diameter & LESS myoglobin
- glycolysis primary source of ATP
- fatigue more readily

Fast Twitch Fibers; 2-3xfaster than slow twitch
- brief, rapid, powerful contractions
- can be oxidative or glycolytic
- eyes and hands

Slow Fibers: less sarcoplasmic reticulum and pumps Ca 2+ slowly
- Ca 2+ remain longer in cytosol, muscle twitch last about 5x
- running, walking, dancing, swimming, riding bicycle

83
Q

Immune System

Know Def of bold terms

PATHOGEN
IMMUNE SYSTEM

A

Pathogen: any disease- causing agent

Immune system: first lines of defense help prevent pathogens from gaining entrance to body

84
Q

Immune System

Active vs Passive Immunity

A

Active Immunity: develop introduction of antigens into body through IMMUNIZATION (making your own)

Passive Immunity: IgG antibodies in blood of pregnant female cross placenta to her fetus
> antibodies in the recipient are produced by another individual (transferred) ( does not involve recipients B or T cells)

85
Q

Immune System
Innate vs Adaptive immunity (in detail)

A

Innate immunity: General (all animals)
- traits shared by broad ranges of pathogens, using SMALL set of receptors
- rapid response

Adaptive Immunity: (vertebrates only)
- Traits SPECIFIC to particular pathogens, using VAST ARRAY of receptors
- slower response

86
Q

Immune System
Innate vs. Adaptive Immunity

Cell types involved and their functions

A

Innate Immunity:
-Phagocytic cells: (cellular eating) Neutrophils = circulate in blood, Macrophages = attract signals from infected tissues “Help” Signals & encounter pathogens;
Dendritic cells: tissues that contact external environment

-Natural Killer Cells: release chemicals that lead to cell death

-Antimicrobial proteins: ward off microbial pathogens
Interferons: proteins provided innate defense by interfering with viral infections

-Inflammatory response:
Histamine: Signaling molecule stored in vesicles of MAST cells in connective (released at site of damage and triggers nearby blood vessels to dilate and become more permeable (swelling)
Cytokines: promote blood flow to the site of injury or infection

Adaptive Immunity
-Cytotoxic cells
- T cells: mature in thymus gland
Effector: Helper T & Cytotoxic T cells
- B cells: mature in bone marrow
Effector: Plasma Cells

Memory: Long- lived
Effector: short lived

87
Q

Immune System
What contributes to inflammatory response?

A

Severe tissue damage or infection that leads to response that is SYSTEMIC
- fever
- # of white blood cells increase
- signaling may recruit additional neutrophils from bone marrow

88
Q

Immune System
How antibodies are formed and how they work?

A

Antibodies are produced by B cells,
Antigen comes in contact, B cells divide and Clone
Cloned B cells -plasma cells- release million antibodies in your bloodstream

89
Q

Viruses
Structure of a Virus

A

Viruses are NOT Cells
Consist of
- protein coat (capsid)
- Genetic material (DNA or RNA)

  • some have membraneous envelopes
  • some have accessory structures that facilitate entry into a cell
90
Q

Viruses
Bacteriophages
a. Structure

A

Viruses that infect bacteria
- elongated capsid head that encloses their DNA
- protein tail attaches the phage to the host and injects the DNA phage inside

91
Q

Viruses
Bacteriophages
b. Host

A

Obligate intracellular parasites (cannot survive w/o a host)
- cannot replicate on their own
- Has HOST RANGE: limited # of host cells that can infect

92
Q

Viruses
Bacteriophages
c. Replicative cycles (lytic vs lysogenic)

A

Lytic Cycle = Virulent Phage
- results in death of the host cell

Lysogenic Cycle = Temperate Phage
- Replicates phage genome W/O destroying the host
- ONLY REPLICATE GENOME

93
Q

Viruses
Classification & Characteristics of viruses (esp how retroviruses diff from others)

A

Viral Envelopes:
- viral glycoproteins= bind specific receptor molec on surface to a host cell

  • Retroviruses: REVERSE TRANSCRIPTASE (enzyme) to copy their RNA genome into DNA
    – Lead to HIV (retrovirus) that causes AID
  • Provirus: Viral DNA that is integrated into host genome
    – permanent resident of host cell
    –RNA, DNA, host genome, Provirus
94
Q

Viruses
Prions- What are they? How do they cause infection?

A

Prions: infectious proteins that appear to cause degenerative brain diseases in animals

How? Incorrectly fold proteins that can be transmitted in food, act slowly, and are virtually indestructible