Exam 3 - Nervous System Flashcards

1
Q

What are the main functions of the nervous system?

A
  • sensory input
  • integration
  • motor output
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2
Q

What is involved in sensory input?

A
  • receptors respond to external/internal stimuli

- relay message to brain and spinal cord

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3
Q

What is involved in integration?

A

brain and spinal cord integrate data and send nerve pulses back out

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4
Q

What is involved in motor output?

A

impulses go to effectors, such as the muscles and glands

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5
Q

What are the characteristics of the central nervous system?

A
  • consists of brain and spinal cord enclosed in boy coverings
  • serves as an integration center
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6
Q

What are the characteristics of the peripheral nervous system?

A
  • consists of nerves and ganglions

- serves to deliver and send information to and from CNS

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7
Q

What are the characteristics of afferent/sensory neurons?

A
  • specialized neurons to detect stimuli
  • starts in PNS and travels to CNS
  • functions to deliver information about environment or condition of the body to the CNS
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8
Q

What are the characteristics of interneurons?

A
  • located in CNS

- functions to receive and integrate information

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9
Q

What are the characteristics of efferent/motor neurons?

A

-send signals from the CNS to effectors of the PNS, such as muscles, organs, and glands

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10
Q

What are the two types of motor neurons, and when do they predominate?

A
  • sympathetic neurons: during fight or flight

- parasympathetic neurons: during relaxtation

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11
Q

How do hormones and neurons control the post-absorptive state?

A
  • sympathetic nervous system interacts with several hormones to control events of post-absorptive state
  • post-absorptive state is triggered by reduced insulin release as blood glucose levels drop
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12
Q

Why is the lipid bilayer membrane surrounding a neuron impermeable to ions?

A
  • ions must pass through channels to enter or exit the neuron
  • some channels require activation to open and allow passage of ions
  • these ion channels are sensitive to the environment and can change their shape
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13
Q

What are the characteristics of voltage-gated ion channels?

A
  • ion channels that change their structure in response to voltage changes
  • structural changes in protein allow or prevent ion movement
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14
Q

What are the characteristics of ligand-gated ion channels?

A
  • ion channels that change structure in response to a chemical binding to a receptor
  • typical ligands include neurotransmitters
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15
Q

What are the characteristics of leak channels?

A
  • generally open, but may open and close at random

- no actual event that opens the channel; rather, an intrinsic rate of switching between the open and closed states

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16
Q

What is the resting membrane potential of a neuron?

A

approximately -70 millivolts

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17
Q

What is depolarization?

A

when the charges inside and outside the cell become less separated

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18
Q

What is hyperpolarization?

A

when the charges inside and outside the cell become more separated

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19
Q

What repolarization?

A

when charges begin to move, leading neurons from a depolarized to a polarized state

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20
Q

What structure is needed to return neuron cells to the original ionic conditions?

A

Na+/K+ pump

21
Q

How do Na+ and K+ concentrations look for a typical cell at resting membrane potential?

A
  • Na+ conc. is higher outside the cell than inside

- K+ conc. is higher inside the cell than outside

22
Q

Which ion has more leak channels - K+ or Na+?

23
Q

What are local/action potentials?

A

changes in RMP created by the movement of ions

24
Q

How do local potentials and action potentials differ?

A
  • local potentials occur when changes in RMP allow ions to move at the dendrites
  • action potentials occur when local potentials are large enough for ion movement to occur along the axons
25
What are the characteristics of local potentials?
- triggered by stimuli and/or neurotransmitters - can depolarize or hyperpolarize membrane - local - graded - reversible if threshold not reached
26
What are the characteristics of action potentials?
- always depolarize | - regulated by voltage-gated ion channels
27
What is the threshold for the "firing" of an action potential?
-55 mV
28
What are the 6 steps of an action potential?
- at rest - stimulus applied - voltage rises - voltage falls - end of action potential - return to rest
29
When does depolarization occur during an action potential?
when the voltage rises
30
When does repolarization occur during an action potential?
when the voltages falls
31
When are sodium ligand-gated channels open?
when the stimulus to generate an action potential is applied
32
When are sodium voltage-gated channels open?
when voltage is rising
33
When are potassium voltage-gated channels open?
when voltage is falling
34
When are potassium ligand-gated channels open?
at the end of the action potential
35
What is the voltage at peak depolarization?
+30 mV
36
How do action potentials move from neuron to neuron?
when a nerve impulse reaches the end of the axon, a molecule is released that stimulates depolarization of the next neuron in the chain
37
What is neuronal secretion?
process of converting the electrical signal of the presynaptic neuron to a chemical signal in the synapse and then back to an electrical signal in the postsynaptic neuron
38
What is involved in the neuronal secretion process?
- presynaptic neuron synthesizes and packages neurotransmitter in synaptic vesicles in the synaptic terminal - action potential causes release of neurotransmitter - neurotransmitter diffuses across the synaptic cleft and is received by postsynaptic cell
39
What types of neurotransmitters can be released by presynaptic cells?
- excitatory | - inhibitory
40
What is summation/
the sum of all local potential changes at the synapses of a postsynaptic cell
41
What is excitatory postsynaptic potential?
brings membrane potential toward threshold
42
What channels are open during EPSP?
sodium ligand-gated channels
43
What is inhibitory postsynaptic potential?
moves membrane potential father from threshold
44
What channels are open during IPSP?
potassium ligand-gated
45
What must happen to the neurotransmitter in order to stop a nerve impulse?
- must be broken down by enzyme | - must be taken back up by neuron
46
What are the physiological roles of dopamine?
- motor control - motivation - arousal - cognitive control - reinforcement and reward
47
What are the characteristics of ADHD?
- may be due to abnormal levels of dopamine - overabundance of dopamine receptors on pre-synaptic cell - prevent continued stimulation of post-synaptic cell and prevent propagation of nerve impulse
48
How does Ritalin help those with ADHD?
- acts by blocking actions of the dopamine re-uptake receptor - dopamine stays around and can transmit impulse to post-synaptic cell