Exam 2 - Human Nutrient Use and Metabolism Flashcards

1
Q

What are the characteristics of carbohydrates?

A
  • digested into small pieces, glucose or other sugar, that is absorbed into blood cells
  • can only be stored in limited quantities so body is eager to use them
  • excess stored in the liver as glucose or glycogen
  • also stored in muscle and nervous tissues
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2
Q

What are the characteristics of fats?

A
  • broken down into fatty acids which can travel in the blood freely or associated with protein
  • stored as triglycerides in fat cells
  • typically provide more than half of the body’s energy needs
  • excess carbs also stored as fatty acids
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3
Q

What are the characteristics of proteins?

A
  • broken down into amino acids that are then used to build new proteins
  • can yield energy when there is a shortage of fats or carbs
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4
Q

If all three nutrients are abundant in the diet…

A
  • carbs and fats will be used primarily for energy

- proteins from food are broken down to provide AAs for proteins

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5
Q

What is anabolism?

A

-synthesizing large molecules from small ones

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6
Q

What is catabolism?

A

-breaking down complex molecules to simpler ones

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7
Q

What is gluconeogenesis?

A

synthesis of glucose from a non-carbohydrate precursor

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8
Q

What is glycogenesis?

A

synthesis of glycogen from glucose

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9
Q

What is glycogenolysis?

A

breakdown of glycogen to form glucose

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10
Q

What is lipogenesis?

A

excess glucose is converted to fat

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11
Q

What is lipolysis?

A

breakdown of stored fats into glycerol and fatty acids

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12
Q

What is ketogenesis?

A

production of ketone bodies from breakdown of fatty acids

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13
Q

What is the catabolic-anabolic steady state?

A

dynamic state in which organic molecules (except DNA) are continuously broken down and rebuilt

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14
Q

What are the characteristics of nutrient pools?

A
  • available for immediate use
  • stores of amino acids, carbohydrates, and fats
  • inter-convertible
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15
Q

What are the characteristics of the amino acid pool?

A
  • body’s total supply of FREE amino acids
  • source for resynthesizing body proteins, forming amino acid derivatives, and gluconeogenesis
  • not stored as proteins
  • must be converted to a citric acid cycle keto acid to be used for energy
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16
Q

What are the characteristics of carbohydrate and fat pools?

A
  • easily interconverted
  • oxidized directly to produce energy in mitochondria
  • can be stored as carbohydrates and fats
17
Q

What is the absorptive state?

A

period right after eating a meal; everything needed for energy production is used and the rest is stored

18
Q

What is the post-absorptive state?

A

in between meals; use what is stored to provide energy

19
Q

What are the characteristics of the absorptive state?

A
  • lasts about 4 hours after eating
  • anabolism exceeds catabolism
  • excess nutrients stored mainly as fats, as well as carbs
20
Q

What are the characteristics of the sympathetic nervous system?

A
  • arouses body for “fight or flight” response

- neurotransmitter is norepinephrine

21
Q

What are the characteristics of the parasympathetic nervous system?

A
  • predominates during relaxation, “rest and digest”

- neurotransmitter is acetylcholine

22
Q

What is the role of the endocrine system?

A
  • hormones involved in blood glucose regulation are insulin and glucagon
  • both produced by the pancreas
23
Q

What stimulated insulin secretion from pancreatic beta cells?

A

elevated blood levels of glucose and amino acids

24
Q

What is the role of insulin?

A

to bind membrane receptors and facilitate the diffusion of glucose into muscle and adipose cells

25
Q

Which organs do not require insulin in order to take up glucose?

A
  • brain

- liver

26
Q

What are the characteristics of the post-absorptive state?

A
  • energy sources supplied by body’s reserves
  • catabolism exceeds anabolism
  • goal is to maintain blood glucose between meals
27
Q

What are the sources of blood glucose during the post-absorptive state?

A
  • glycogenolysis in the liver
  • glyogenolysis in the skeletal muscle
  • lipolysis in adipose tissues and liver
  • catabolism of cellular protein
28
Q

What is glucose sparing?

A

the body’s use of non-carbohydrate energy sources during long periods of fasting in order to conserve glucose

29
Q

What stimulates the release of glucagon from the pancreas?

A
  • declining blood glucose levels

- rising amino acid levels

30
Q

What are the two types of diabetes mellitus?

A
  • Type 1: inadequate insulin production

- Type 2: abnormal insulin receptors

31
Q

What does diabetes result in?

A
  • unavailability of glucose to most body cells
  • excessively high blood glucose levels
  • glucose loss in urine
  • metabolic acidosis, protein wasting, and weight loss
  • coma and death