Exam 3 Material Flashcards
Which of the following accurately describes the olfactory system:
Odorant molecules bind to receptors on the mitral cells in the olfactory bulb
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The olfactory epithelium is a part of the olfactory bulb
, Not Selected
Olfactory sensory neurons are arranged topographically in the epithelium, but its axons project randomly onto mitral cells
, Not Selected
Correct answer:
Olfactory sensory neurons synapse with mitral cells in the glomeruli within the olfactory bulb
Olfactory sensory neurons synapse with mitral cells in the glomeruli within the olfactory bulb
The total inability to smell, most often resulting from sinus or viral infection or physical damage from an accident, is known as
Agnosia
, Not Selected
Parosmia
, Not Selected
Hyposmia
, Not Selected
Correct answer:
Anosmia
Anosmia
Which of the following is FALSE regarding the olfactory transduction cascade
Golf activates the enzyme adenylate cyclase
, Not Selected
Adenylate cyclase raises intracellular cyclic AMP (cAMP)
, Not Selected
Correct answer:
Activation of the olfactory receptor by an odorant results in a membrane hyperpolarization
Rising cAMP levels opens cAMP-gated ion channels that allow Na+ and Ca2+ to enter the cell
, Not Selected
Binding of a “preferred” odorant to olfactory receptor molecule activates the G-protein Golf
Activation of the olfactory receptor by an odorant results in a membrane hyperpolarization
Activation of the olfactory receptor by an odorant results in a membrane hyperpolarization
Chemoreception
the detection of chemicals using olfactory sensory cells
Olfaction
sniffing in and perceiving odors
through our nostrils
Orthonasal olfaction
exhaling odorant molecules into
our mouth, where they can travel up into our upper nasal cavity
Retronasal Olfaction
Odorant
a molecule that can be smelled
Olfactory Bulb
a neural structure of the vertebrate forebrain
involved the sense of smell
Glomeruli
Discrete spheres of nerve tissue; formed from
the axons of the olfactory sensory neurons and dendrites of
mitral cells
Mitral Cells
Interneurons in the olfactory bulb, whose axons
pass information to other parts of the brain
Volatile
a molecule that is
buoyant in air and can
be inhaled
Turbinates
curled bony protrusions that create turbulence to
incoming air
Olfactory Epithelium
mucus membrane in the roof of the nasal
cavity that houses the olfactory sensory neurons (OSNs)
Olfactory Sensory Neurons (OSNs)
a transduction cell within the
olfactory epithelium
small neurons in
the mucous layer of the olfactory epithelium that
contain the receptor sites for odorant molecules
Olfactory Receptor Molecules
A large family of G-protein coupled
receptors that are expressed in the cilia of olfactory sensory neurons and
bind to odorants
Olfactory sensory neurons can be _______________ regularly throughout
adulthood
Replaced
Olfactory Transduction Cascade
A series of events that starts with a
chemical (odorant) binding to the olfactory receptor molecule and ends
with a change in the membrane potential of an olfactory sensory neuron
Each odorant activates only a _________ of olfactory sensory neurons
Subset
Chemotopy
Orderly mapping between odorant structure and spatial
location of activated glomeruli
Mitral Cells receive input
from just________
one glomerulus
Granule Cell
most numerous type of neuron in the olfactory bulb and
interconnect mitral cells; do not have axons
Reciprocal dendro-dendritic synapses
synapses between dendrites that are
arranged so that a synapse that transmits signals in one direction, lies adjacent to
a synapse going in the other direction
Shutting down activity shortly after it has begun likely keeps
the system sensitive to ________________ odors
new or changing