Exam 3: Drugs Used In Coagulation Disorders Flashcards
0
Q
Antidote for heparin toxicity?
A
Protamine sulfate
1
Q
Antidote for warfarin toxicity
A
Vit K and FFP
2
Q
All are the functions of hemostasis except: A. Keep fluidity of the blood B. Repair vascular injury C. Defense against foreign substances D. Limit blood loss
A
C
3
Q
2 main functions of thromboxane A2 (TXA2): A. Vasodilate B. Vasoconstrict C. Form primary platelet plug D. Form secondary platelet plug Choose 2
A
B and C
4
Q
TXA is made from ________ using the ____________ pathway:
A. Prostaglandin, lipoxygenase
B. Arachidonic acid, lipoxygenase
C. Pregnenolone, COX
A
B
5
Q
Platelet granules contain all except: A. ADP B. 5-HT C. Histamine D. A and B E. All of the above
A
D
6
Q
Aprotinin is a serine protease inhibitor that inhibits fibrinolysis by: Choose 2 A. Free plasmin B. Bound plasmin C. Plasmin-streptokinase complex D. Inhibits production of serine
A
A and C
7
Q
Aminocaproic acid (EACA) is chemically similar which aa? A. Cysteine B. Serine C. Leucine D. Lysine
A
D
8
Q
MOA of aminocaproic acid (EACA)?
A. Inhibits serine protease inhibitor
B. Inhibits plasminogen activator
C. Inhibits free plasmin
A
B
9
Q
This drug blocks 2B/3A receptor complex A. Abcximab B. Alteplase C. Urokinase D. Clopidogrel
A
A
10
Q
PDE inhibitor that vasodilates and causes platelet aggregation. Used to treat intermittent claudication: A. Clopidogrel B. Cilostazol C. Eptifibatide D. Warfarin
A
B
11
Q
Drug used for pts with unstable angina and NSTEMI in combo with aspirin: A. Clopidogrel B. Cilostazol C. Eptifibatide D. Warfarin
A
A
12
Q
Adverse SE of clopidogrel: A. Gynecomastia B. Alopecia C. Neutropenia D. Erythema
A
C
13
Q
Drug given for prevention of stroke in patients with history of TIA: A. Clopidogrel B. Cilostazol C. Ticlopidine D. Warfarin
A
C
