Exam 2 (Thermoregulation) Flashcards
What does Q10 measure and what is the equation for it?
How many times faster a reaction occurs when the temperature is increased by 10 C
Q10 = (R2/R1)(10/T2 - T1)
Which type of metabolism is temperature dependent?
Aerobic
What is the difference between temperature and heat?
Temperature is the mean KE of molecules in a system; heat is the total KE in a system
What is the equation for the rate of heat exchange between two objects?
rate = kA(T2 - T1)/d
What are the two types of convection?
Free: heat flow due to temperature differences
Forced: heat flow due to an external force
What is the equation for thermal radiation?
Hrad = Œσ(Ts4)
What is Gular flutter?
Bird panting; a strategy for evaporative heat loss
What are the involuntary methods of thermogenesis?
- shivering
- uncoupling proteins
- brown adipose tissue
- futile cycles
What part of the hypothalamus manages temperature regulation?
pre-optic area (POA)
What are the set point and sensors for temperature in the POA?
SP: temperature-insensitive neurons (Q10 = 1)
warm-sensitive neurons (Q10 > 1)
cold-sensitive neurons (Q10 < 1)
What is the function of motor neurons in thermoregulation?
connect hypothalamic neurons to effectors; integrate information from multiple hypothalamic neurons
What is the function of PGE?
increase Tset in POA
[PGE] is increased by pyrogens
What pyrogens increase PGE?
IL1; IL6 from white blood cells
LBS from exogenous sources
What is the point of a fever?
increases the growth rate of gram+ bacteria, which use up the iron supply in the blood
subsequent lack of iron causes population crash