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AU14 SE and Treatments > Exam 2 SE > Flashcards

Exam 2 SE Flashcards

1
Q

SE: akathesia

A

schizophrenia/anti-psychotics (inhibit dopamenergic neurons)

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2
Q

SE: allergic reactions/hypersentitivity

A

ester LAs (inhibit NE reuptake)L DOPA + carbidopa?

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3
Q

SE: anti-emetic

A

propofol (GA, activate GABA receptor)cannabinoids (binds cannabinoid receptor)

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4
Q

SE: anti-tussive

A

codeine (partial opiate agonist)

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5
Q

SE: constipation

A

opiods

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6
Q

SE: dissociated amnesia

A

ketamine (GA, inhibit glutamate receptor)

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7
Q

SE: dystonia

A

schizophrenia/anti-psychotics (inhibit dopamenergic neurons)

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8
Q

SE: fetal damage

A

sodium valproate (inc GABA synthesis and dec GABA breakdown)

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9
Q

SE: fetal hydantoin syndrome

A

phenytoin (inhibits Na+ channels in brain)

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10
Q

SE: low birth weight

A

cocaine (prevents reuptake of NE, 5HT, DA)

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11
Q

SE: gingival hyperplasia

A

phenytoin (inhibits Na+ channels in brain)

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12
Q

SE: glaucoma

A

LDOPA + carbidopa (precursor of DA + DOPA decarboxylase inhibitior)

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13
Q

SE: hallucinations

A

ketamineParkinson’s drugscocaine (prevents reuptake of NE, 5HT, DA)MAO inhibitors (a-d, inhibit NE, 5HT metabolism)ie tranylcypromine, phenelzine, isocarboxazid

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14
Q

SE: hepatitis

A

dantrolene (LA, inhibits Ca++ release from muscle sarcoplasmic reticulum)sodium valproate (inc GABA synthesis and dec GABA breakdown)

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15
Q

SE: hypertesive crisis

A

MAO inhibitors (a-d, inhibit NE, 5HT metabolism)ie tranylcypromine, phenelzine, isocarboxazid

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16
Q

SE: (postural) hypotension

A

L DOPA + carbidopa (precursor of DA + DOPA decarboxylase inhibitior)dopamine agonistsschizophrenia/anti-psychotics (inhibit dopamenergic neurons)MAO inhibitors (a-d, inhibit NE, 5HT metabolism)ie tranylcypromine, phenelzine, isocarboxazid

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17
Q

SE: hypothyroidism

A

lithium (manic, dec NE release)

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18
Q

SE: insomnia

A

selegiline –> methanphetamine (inihbit MAO)

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19
Q

SE: leukemia

A

nitrous oxide (GA, activate GABAergic, inhibit gluaminergic)

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20
Q

SE: liver disease

A

“flurane”s = hydrogenated hydrocarbons (GA, activate GABAergic, inhibit gluaminergic) MAO inhibitors (a-d, inhibit NE, 5HT metabolism)ie tranylcypromine, phenelzine, isocarboxazid

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21
Q

SE: lupus-like syndrome

A

procainamide (amino acid LA)

22
Q

SE: malignant hyperthermia

A

“flurane”s = hydrogenated hydrocarbons (treat with dantrolene) (GA, activate GABAergic, inhibit gluaminergic)

23
Q

SE: “manic”-like disorders

A

dopamine agoinsts

24
Q

SE: neurotic malignant syndrome

A

discontinuation of LDOPA + carbidopa (precursor of DA + DOPA decarboxylase inhibitior)schizophrenia/anti-psychotics (inhibit dopamenergic neurons)

25
Q

SE: nystagmus

A

lithium (manic, dec NE release)

26
Q

SE: Parkinson’s-like symptoms

A

schizophrenia/anti-psychotics (inhibit dopamenergic neurons)

27
Q

SE: pupil constriction

A

opiods (not with meperidine)

28
Q

SE: renal failure

A

1st generation anti-depressants (tricyclic) (inhibit NE reuptke)ie imipramine, amitriptyline

29
Q

SE: sleep “attacks”

A

dopamine agonists

30
Q

SE: sleep driving, izarre behavior, hallucinations/nightmares, dec inhibitions

A

non-benzodiazepine hypnotics “z” drugs(bind alpha subunit of benzo receptor)ie zolpidem, zalepion, eszopiclone

31
Q

SE: spina bifida

A

carbamazepine (anti-epileptic, inhibit Na+ channels)

32
Q

SE: Stevens-Johnson syndrome

A

phenytoin (inhibits Na+ channels in brain)

33
Q

SE: tardive dyskinesia

A

schizophrenia/anti-psychotics (inhibit dopamenergic neurons)

34
Q

SE: tinnitus

A

LAs

35
Q

SE: urticaria

A

cocaine (prevents reuptake of NE, 5HT, DA)

36
Q

Treats: ADD

A

amphetamine, methamphetamine, methylphenidate (inc release of DA + NE)

37
Q

Treats: benzodiazepine overdose

A

flumazenil (benzo receptor blocker)

38
Q

Treats: cardiac arrhythmia

A

procainamide, lidocaine (amino acid LAs)

39
Q

Treats: epilepsy

A

barbiturates, “ital”s (enhance action of GABA)

40
Q

Treats: glaucoma

A

cannabinoids (bind cannabinoid receptor)

41
Q

Treats: heroine overdose

A

opiate antagonists (bind and block opiate receptor)ie naloxone, naltrexone, methylnaltrexone

42
Q

Treats: malignant hyperthermia

A

dantrolene (LA, inhibits Ca++ release from muscle sarcoplasmic reticulum)

43
Q

Treats: methanol poisoning

A

fomepizole (inhibits alcohol dehydrogenase)

44
Q

Treats: narcolepsy

A

amphetamine, methamphetamine, metylphenidate (inc release of DA + NE)

45
Q

Treats: nicotine addiction

A

varenicline (partial nicotinic agonist)

46
Q

Treats: restless leg syndrome

A

pramipexole, ropinirole (DA agonists)

47
Q

Treats: Tourettes, hiccups, OCD, stuttering, migranes

A

schizophrenia/anti-psychotics (inhibit dopamenergic neurons)

48
Q

1st pass metabolism

A

flumazenil (benzo receptor blocker)rotigotine (dopamine agonist, patch)morphine (natural opiate agonist)

49
Q

contra-indicated with ethanol

A

benzodiazepines (activate benzo receptor sites)barbiturates “ital”s (enhance action of GABA)”-melteon”s (melatonin receptor agonist)schizophrenia/anti-psychotics (inhibit dopamenergic neurons)

50
Q

contra-indicated with indirect acting amines (ie tyramine)

A

MAO inhibitors (a-d, inhibit NE, 5HT metabolism)ie tranylcypromine, phenelzine, isocarboxazid

51
Q

P450

A

amino acid LAscarbamazepine (inhibits Na+ channels)phenobarbital (activates GABAergic neurons)2nd genreation antidepressants (SSRIs)

AU14 SE and Treatments (5 decks)

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