Exam 2 Puruvate Oxidation Flashcards
What is pyruvate oxidation?
It is the process by which pyruvate is converted into acetyl-CoA, producing NADH and CO2.
True or False: Pyruvate oxidation occurs in the cytoplasm of the cell.
False: It occurs in the mitochondria.
What is the primary enzyme involved in pyruvate oxidation?
Pyruvate dehydrogenase.
Fill in the blank: Pyruvate oxidation links glycolysis to __________.
the citric acid cycle.
What are the products of one molecule of pyruvate undergoing oxidation?
One molecule of acetyl-CoA, one molecule of NADH, and one molecule of CO2.
Multiple Choice: Which of the following is a cofactor required for pyruvate dehydrogenase activity? A) Coenzyme A B) NAD+ C) Both A and B D) None of the above
C) Both A and B.
What role does NAD+ play in pyruvate oxidation?
It acts as an electron acceptor, being reduced to NADH.
True or False: Pyruvate oxidation is an aerobic process.
True: It requires oxygen indirectly, as it feeds into aerobic respiration.
What happens to the carbon atoms in pyruvate during oxidation?
One carbon atom is released as CO2.
Short Answer: How many pyruvate molecules are produced from one glucose molecule during glycolysis?
Two pyruvate molecules.
What is the significance of acetyl-CoA in metabolism?
It is a key substrate that enters the citric acid cycle for further energy production.
Fill in the blank: Pyruvate oxidation is regulated by the availability of __________.
substrates and feedback inhibition.
Multiple Choice: Which condition would most likely enhance pyruvate oxidation? A) High levels of NADH B) Low levels of acetyl-CoA C) High levels of NAD+ D) High levels of pyruvate
C) High levels of NAD+.
True or False: Pyruvate can be converted into lactate under anaerobic conditions.
True.
What is the fate of acetyl-CoA after pyruvate oxidation?
It enters the citric acid cycle for further oxidation.
