EXAM 2 Part 2 Flashcards
EVOLUTION
Change in the allele frequency of a population over generations.
What is the NEW SYNTHESIS
The combination of the theories of Mendel and Darwin. Mendel reveled the mechanism of inheritance and Darwin
HARDY WEINBERG EQUILIBRIUM
Genotype frequencies and gene frequencies of a large randomly mating population remain constant provided that immigration , mutation and selection do not take place.
A population is fixed when
All the individuals are homozygous for one allele. Fixed at “a” allele for example
A population with GENETIC VARIATION
Is one where there is multiple type alleles in the population. Population is not fixed at a gene locus.
The assumptions of the H-W equilibrium model. That allele frequencies can predict the genes type frequencies in the next population in if:
- Large population size
- No mutation
- No Migration
- No selection
- Mating is random ( non assortive mating)
As long as the H-w assumptions are not violated what happens to the frequency of the alleles and tthe frequency of genotype
- The frequency of alleles is the same in each generation
2. The number of individual with each genotype is the same each generation
Why do we use h-w equil
To test if a population is evolving
can occur with more that 2 sets of alleles
If a population is not in H-w equilibrium
Then one of the requirements have been violated and the population is evolving.
Violation of the “ large population” assumption
Small population
How can a small population affect HW
GENETIC DRIFT
. BOTTLENECK EFFECT
. FOUNDERS EFFECT
GENETIC DRIFT IS
The frequency of alleles in a population fluctuate due to random events ( by chance)
. A violation of HW “ small population
. When a percentage who are selected to mate are chosen by chance in a small population, it does not reflect the true genotype of the population as it would in a large population.
BOTTLENECK EFFECT
Is a type of GENETIC DRIFT
. VIOLTION OF LARGE POPULATION ASSUMPTION OF HW
.It is when a population has a major shrinking event ( population drops rapidly over a short period) causing the loss of many alleles that were present in the original population and the surviving population( allele frequency) is not representative of the original population.
. There is a loss in genetic diversity- a single change in the environment might doom them all.
Eg of bottleneck effect
red wolves that are highly endangered whose population allele variety is greatly reduced from the original population
FOUNDERS EFFECT
Genetic drift that occurs when a few individuals become isolated from a larger population and form a new population whose gene pool composition is not reflective of that of the original population.
by chance the founding population have different allele frequency from the original. A
Eg of FOUNDERS EFFECT
In North America the Pennsylvania Amish settled away from their original population, and by chance one of the founding population carried an allele for short limb dwarfism and extra fingers which is recessive in the original population and extremely rare. In the isolated Amish population intermarriage has kept the disease incidence high in the small population.
Violation of “ no mutation”
Mutation of introduces new alleles in the population would change the overall allele frequency.
Mutations are rare events in population
Violation to “ no migration “ assumption of H W
. Gene flow
GENE FLOW
results from migration. Movement of alleles into or out of a population.
Eg of GENE FLOW
Grass have developed a hightolerance to the polluted soil of mine tailings while grass grown off the mine tailings have low tolerance, however there is not a 100 % tolerance. Wind has blown pollen/ from grass off the mine tailing to area of grass on the mine tailing. Gene flow from low tolerance seed has constrained perfect tolerance of high tolerance France on the polluted soil.
Violation of “ random mating “ of H-W
ASSORTATIVE MATING
ASSORTATIVE MATING
Individuals choosing mates that a similar phenotype or genotype to their own. ( POSITIVE ASSORTATIVE MATING)
NEGATIVE ASSORTATIVE MATING choosing the opposite phenotype or genotype in a mate
Eg. Of ASSORTATIVE MATING
A population that is original homozygous and all it’s individuals mate by ASSORTATIVE mating the future population will remain constant. An over abundance of homozygotes
. In diaprepes weevils found in the Caribbean large females tend to mate with large males and small females are left to mate with small males.
EG. NEGATIVE ASSORTMENT
negative ASSORTATIVE mating tend to result in more allele diversity in the population - an over abundance of heterozygotes.
. Preference based on MHC in mammals ( immune function) MHC are genes that help the immune system detect foreign substance. Certain mice tend to mate with individuals with a different MHC than their own.