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exam 2 other Flashcards

1
Q

MOST likely to be associated with elevation of citrate in the blood or kidney tissue

A

fluoroacetate

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2
Q

A toxicant that has the following lesions in most species: gastroenteritis which may be hemorrhagic, pulmonary congestion and edema, congestion of liver and kidney, in addition to the odor of dead fish (acteylene odor) in the stomach may be poisoned with

A

zinc phosphide

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3
Q

what drug would you use to reduce brain swelling due to toxicosis in animals

A

glucocorticoid

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4
Q

Which of the following are LEAST likely clinical signs of fluoroacetate (compound 1080) toxicosis in the horse?

a. colic, trembling, and staggering
b. tachycardia, cardiac arrhythmias, and ventricular fibrillation
c. clonic-tonic convulsive seizures and opisthotonos
d. signs of respiratory insufficiency

A

c. clonic-tonic convulsive seizures and opisthotonos

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5
Q

MOST sensitive animals to fluoroacetate toxicosis are

A

dogs

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6
Q

Which of the following is LEAST likely concerning paraquat toxicosis?

a. Onset of respiratory signs is within 1-4 hours
b. Signs in dogs and cats include vomiting, CNS depression, and severe dyspnea
c. Lesions include pulmonary edema, congestion, and hemorrhage, and may be lingual ulcers
d. Death is due to difficulty in gaseous exchange resulting from lung damage

A

A.

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7
Q

causes signs of respiratory insufficiency and overheating MAINLY by uncoupling oxidative phosphorylation and blocking or decreasing ATP

A

PCP

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8
Q

T/F

A negative ethylene glycol test in cats means that the cat has not been exposed to a toxic level of ethylene glycol

A

FALSE

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9
Q

most sensitive species to ethylene glycol

A

cats

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10
Q

Acute renal failure as a result of ethylene glycol toxicosis usually occurs how long after ingestion in the dog

A

24-72 hours after ingestion

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11
Q

Adding 20% ferric chloride to urine sample results in purple color urine is used to detect the presence of which toxicant in urine

A

phenol

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12
Q

The MOST toxic detergents are

a. soaps
b. dishwashing liquids
c. laundry detergents
d. automatic dishwashing detergents
A

D

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13
Q

T/F

high energy diet will increase urea toxicity

A

FALSE

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14
Q

The clinical signs associated with water deprivation/sodium ion toxicosis in swine are thought to be MAINLY caused by

A

cerebral edema and overhydration of nerve cells

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15
Q

T/F
Urea is commonly used in ruminants as a feed additive because it is an economical and efficient source of protein and minerals such as sulfur and phosphorus

A

FALSE

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16
Q

this metal toxicosis causes inhibition of the activity of several enzymes in heme synthesis

A

lead

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17
Q

The diagnosis of lead toxicosis in dogs is BEST established on the basis of

A

blood levels

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18
Q

Inhibition of lipoic acid which results in inhibition of citric acid cycle is the mechanism of action of

A

trivalent arsenic

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19
Q

The MOST susceptible animals to iron toxicosis are

A

pigs and dogs

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20
Q

• Cholecalciferol is used in humans for what

A

psoriasis

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21
Q

The rodenticide that is characterized by acetylene odor is

A

zinc phosphide

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22
Q

Vitamin D3 rodenticide toxicosis is associated with

A

hypercalcemia

hyperphosphatemia

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23
Q

Which of the following rodenticides causes cerebral and spinal edema MAINLY by uncoupling oxidative phosphorylation and inhibiting ATP

A

bromethalin

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24
Q

A dog showing signs of anorexia, vomiting blood, cardiac arrhythmias, polyuria and polydipsia is MOST likely intoxicated with

A

cholecalciferol

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25
The route of choice for administration of vitamin K is
PO
26
mechanism of action of anticagulant rodenticides
They inhibit activation of precursor proteins of clotting factors II, VII, IX, and Xz
27
Administration of the following drug may increase warfarin toxicity EXCEPT a. aspirin b. sulfonamides c. phenobarbital d. steroids e. thyroxine
phenobarbital
28
What is the BEST sample, for chemical analysis, to help confirm a diagnosis of cholecalciferol toxicosis in a live German shepard dog
serum
29
toxic agent MOST likely to produce degeneration of peripheral neurons is
arsanilic acid
30
Deferoxamine is the chelating agent of choice for
iron
31
Enlarged yellow liver, enlarged friable and hemorrhagic kidneys, enlarged black spleen, and red wine-colored urine are lesions MOST likely associated with
chronic copper toxicosis
32
Reduced cytochrome oxidase in cattle can be used as a diagnostic test in toxicosis with
molybdenum
33
Clinical signs of subacute selenium toxicosis in pigs are genereally similar to toxicosis with
arsenilic acid
34
Poisoning by ingestion of seleniferous plants can be seen in the following states EXCEPT a. South Dakota b. North Dakota c. Wyoming d. Florida e. Montana
not florida
35
. Inhibition of lipoic acid which results in inhibition of citric acid cycle is the mechanism of action of
trivalent arsenic
36
The presence of an odor of rotten garlic in a fresh carcass is suggestive of acute toxicosis with
selenium
37
A dog showing gastrointestinal signs followed by a phase of apparent recovery, which deteriorates into multiorgan failure is MOST likely poisoned with oral
iron
38
The metal toxicosis LEAST likely to cause signs of gastroenteritis is a. lead b. zinc c. inorganic arsenic d. organic arsenic feed additives e. iron
D
39
Ingestion of kerosine is MOST likely to cause
severe aspiration pneumonia
40
The specimen of choice to confirm a diagnosis of chronic fluoride poisoning in a live animal is
bone
41
A selenium indicator plant which is grown widely in the west is
princes plume
42
Late clinical signs of ethylene glycol poisoning are PRIMARILY related to
acute renal failure
43
Which of the following serum parameters is LEAST likely to be elevated in urea toxicosis? a. ammonia b. blood urea nitrogen (BUN) c. glucsose d. pH e. transaminases (ALT, AST)
D - pH
44
If the type of the anticoagulant rodenticide is unknown, duration of vitamin k1 treatment should be...
3-4 weeks
45
T/F Warfarin acts as an anticoagulant in-vivo and in-vitro by inhibiting vitamin K epoxide reductase inhibiting activation of vitamin K-dependent clotting factors.
TRUE
46
T/F Petroleum products of low boiling points, low viscosity, and low surface tension generally have more pneumotoxic potential.
TRUE
47
The specimen of choice for chemical analysis of strychnine in a live animal is
urine
48
Which of the following is LEAST likely to be used in decontamination in strychnine poisoning
antacids
49
Which of the following statements about the mechanism of action of warfarin is TRUE? a. It inhibits production of precursor proteins of clotting factors II, VII, IX, and X b. It increases metabolism of vitamin K-dependent clotting factors c. It activates precursor proteins of clotting factors II, VII, IX, and X d. it stimulates carboxylation of vitamin K-dependent clotting factors e. It inhibits vitamin K epoxide reductase
E.
50
T/F | Administration of vitamin K1 immediately reverses the action of anticoagulant rodenticides.
FALSE
51
Which of the following toxicants is MOST likely to be associated with elevation of citrate in the blood or kidney tissue
fluoroacetate
52
Antidotal (specific) treatment of inorganic arsenic toxicosis is a. sodium thiosulfate orally b. BAL (dimercaprol) IM c. apomorphine SC d. sodium sulfate orally
B
53
All of the following decrease GI absorption of lead EXCEPT a. zinc b. protein c. acidity d. calcium
C
54
hemolytic crisis
copper
55
T/F | chronic copper tox has GI signs
false
56
severe green diarrhea
molybdenum
57
hemolytic anemia
zinc
58
T/F | Renal CS with Zinc and acidosis with Iron
true
59
T/F | cats with ethylene glycol tox have polydipsia
false
60
dog with vomit and lingual ulcers
paraquat
61
acetylene odor
zinc phosphide
62
do not add this to a gastric lavage in a dog poisoned with strychnine
sodium bicarb
63
T/F | phenothiazines will control CNS in styrchnine posion
false
64
what drug will not increase the effects of warfarin
phenobarbital
65
immediate reversal of warfarin by iv infusion of
whole blood
66
strynchine specimen of choice
urine
67
duration of antidotal for unknown rodenticide
3-4 weeks
68
dog anorexic vomit blood arrythymias PU PD
cholecalciferol
69
admin vitmin K
PO
70
sample for cholecalciferol
serum
71
drug to lower bromenthalin brain sweling
glucocorticoid
72
bentonite and fullers earth for
paraquat
73
rapid overheat and dark blood
PCP
74
most sensitive coag test
PIKVA
75
dead animal rodenticide sample
liver
76
presnece of food in tummy incrased tox
zinc phosphide
77
elevates citrate in the blood
fluoroacetate
78
increases ICP and posterior paralysis
bromethalin
79
most senstive to zinc phosphide
cats

TOX (5 decks)

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