Exam 2: Muscle Performance, Muscle Injuries, and Muscle Diseases Flashcards

1
Q

Muscle Performance

Muscle Performance

A

Muscle performance often considerd in terms of:
* Force (power & strength) - Maximum amount of tension produced by a muscle or muscle group
* Endurance - amount of time during which an individual can perform a particular activity
* Inversliy related relationship

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2
Q

Muscle Performance

Muscle Performance

A

Factors determining performance capabilities of a skeletal muscle:
* Type of mucle fibers present in the muscle
* Physical conditioning or traning

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3
Q

Types of skeletal muscle fibers:

Types of skeletal muscle fibers:

A

Slow Fibers (Type I Fibers)
* Slow twitch oxidative fibers
* Aerobic

Intermediate Fibers (Type II-A Fibers)
* Fast twitch oxidative fibers

Fast fibers (Type II-B Fibers)
* Fast twitch Glycolytic Fibers

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4
Q

Slow Fibers

Slow fibers (Red)

A
  • Half the diameter of fast fibers
  • Take three times as long to contract after stimulation
  • Abundant Mitochondria - aerobic, oxidative metabolism
  • Extensive capilary supply
  • High concentration of myoglobin - intracellular pxygen storage molecule
  • can contract for a long period of time - fatigue resistant
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5
Q

Fast Fibers

Fast Fibers (white)

A
  • Large in diamater
  • Contain densley packed myofibrils
  • Large Glycogen reserves
  • Relativley few mitochondria - anaerobic, glycolytic metabolism
  • Priduce rapid, powerful contractions of short duration
  • Fatigue Rapidly
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6
Q

Intermediate Fibers

Intermediate Fibers (Fast twitch oxidative fibers)

A

Fast fibers that gain greater resistance to fatigue in response to aerobic endurance traning
* Additional cappilary cupply
* More mitochondria
* Smaller in diamater
* Not as dependent of anaerobic metabolism (myoglobin)

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7
Q

Muscle Performance and the distrobution of Muscle Fibers

Muscle Performance and the distrobution of Muscle Fibers

A

Percentage of slow fibers and fast fibers genetically determined, can vary consideribly amoung muscles
* Pale (white) muscle - mostly fast fibers
* Dark (red) muscles - dominated by slow fibers

Training can change percentage of fast fibers that have intermediate properties

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8
Q

Muscle Hypertrophy and Atrophy

Muscle Hypertrophy and Atrophy

A
  • Hypertrophy - increase in diameter of muscle
  • Atrophy - decrease in diamater of muscle
  • Change is due to increase or decrease in diamater of muscle fibers within the muscle (number of muscle fibers (cells) does not change
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9
Q

Muscle Hypertrophy and Atrophy

Muscle Hypertrophy and Atrophy

A

Change in diamater of muscle cells
* Increase or decrease depending on level of activity over time
* Increased activity leads to synthesis of more actin and myosin myofilaments
* Decreased activity leads to loos of actin and myosin myofilaments

Long term disuse of muscle can lead to irreversable atrophy in muscle if muscle cells die

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10
Q

Physcial Conditioning Improves Endurnace

Physcial Conditioning Improves Endurnace

A

Aanerobic Endurance
* Time period in which muscular contractions are sustained by glycolosis after depleting ATP and CP reserves

Aerobic Endurance
* Time period in which muscle can continue to contract while supported by mitochondrial activities after depleting ATP/CP reserves

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11
Q

Physical Conditioning

Physical Conditioning

A

Improve anaerobic endurance
* Frequent breif, intesive workouts
* Increase muscle mass
* Increase ATP/CP reserves
* Increase glycogen reserves
* Increase ability to tolerate lactic acid build up

Improve aerobic endurance
* Sustained low levels of activity
* Increased Blood Supply to muscles
* Improve cardiovascular activity

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12
Q

Aging and the Musclar System

Aging and the Musclar System

A

Decrease in size, strength, and endurance of muscles
* Reduction is size and strength due to decrease in number of myofibrils
* Decrease in endurance due to less ATP, CP, Glycogen, and myoglobin

Skeletal Muscles become less elastic
* Develop increasing amounts of fiborus onnective tissue (Fibrosis)

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13
Q

Aging and the Musclar System

Aging and the Musclar System

A

Tolerance for exercise decreases
* Muscles fatigue more quickly
* Reduction in thermoregulatory ability, thus are subject to overheating (Less sweating, less vasodialation = overheating)

Ability to recoverf from muscular injuries decreases
* Nuber of satelite cells decreases with age
* Repair capabilities become more limited, more scar tissue (fibrous tissue) occurs

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14
Q

Muscle System Disorders

Muscle System Disorders

A

Primary disorders - result from problems with the muscular system itself
* Muscle Trauma
* Muscle Infections
* Inherited Disorders
* Tumors

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15
Q

Muscle System Disorders

Muscle System Disorders

A

Secondary Disorders - result of problems originating in other systems
* Nervous system disorders that affect the coordination or control of muscle contraction
* Nutritional or Metabolic Problems that affect electrolyte concentrations or the energy supply available to the muscles
* Cardiovascular Disorders that restrict or reduce blood flow to skeletal muscles

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16
Q

Muscle System Disorders

Muscle System Disorders

A
  1. Muscle spasm (cramp) - strong sudden, usually painful, unwanted contraction
  2. Muscle Spasticity - Excessive muscle tone
  3. Muscle Flaccidity - Very low muscle tone
  4. Muscle Atrophy - Deterioration or wasting due to disease, immobility, or interference with normal motor neuron innervation
  5. Myositis - muscle inflimation (Polymyositis and Dermatomyositis are autoimmune)
  6. Strain - tears in muscle tissue
  7. Sprain - Tears in ligaments or tendons or joint capsule
  8. Paralysis - loss of voluntary motor controll (Flacid or Spastic)`
17
Q

Nervous System Disorders that affect the coordination or control of musc

Nervous System Disorders that affect the coordination or control of muscle contraction

A

Blockage of release of Acetylocholine (EX. botulism)
* Flacid Paralysis

Interference with binding of ACH to receptors
* Flacid Paralysis

Interferance with ACH esterase activity
* Spastic Paralysi - organophosphates, nerve gas, insecticides, neostigmine

Loss of Motot Neuron - polio
* Flacid Paralysis - increased branching of remaining motor neurons

Loss of Motor Neuron Axon - peripheral nerve damage
* FLacid Paralysis

Excesive stimulation of motor neuron - tetanus
* Spastic Paralysis

18
Q

Muscular System Disorders

Muscular System Disorders

A

Inherited Disorders
* Muscular Dystrophies
* Duchenne’s MD - gene on X chromsome
* Early onset
* Myotonic Dystrophy
* Chromosome 19 disorder
* Typically onset after puberty

19
Q

Muscular Trauma

Muscular Trauma

A

Muscle Trauma
* Minor trauma such as damage to myofibrils, sarcolemma from excessive activity
* Major trauma such as laceration, crushing, deep brusies, muscle tear (strain)
* New muscle cell production from satelite cells - limmited ability
* Scar tisue
* Compartment syndrome (can occur from crushing traume)

20
Q

Muscualr System Disorders

Muscualr System Disorders

A

Nutritional or Metabolic Problems
* Can affect the energy supply avalible to the muscles (starvation)
* Can affect electrolyte concentration (dehydration, kidney disease)
* Hyper or Hypo-kalemia (K+)
* Hyper or Hypo-natremia (Na+)
* Hyper or Hypo-calcimia (CA+2)