Exam 2 - Lecture 3 Flashcards

1
Q

what does it mean that IV is the “least forgiving”?

A

immediate distribution; there is no line of defense if something goes wrong

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2
Q

why does IV have rapid onset of action?

A

there is no absorption step

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3
Q

two methods of IV administration

A

bolus (push)
infusion

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4
Q

two sites of IV administration

A

peripheral vein
central vein

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5
Q

what is phlebitis?

A

inflammation from irritation of the tunica intima of the vein

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6
Q

what is thrombosis?

A

formation of a blood clot (thrombus) in the vein

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7
Q

true or false: phlebitis takes hours to subside

A

false

(may take days to months to subside)

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8
Q

true or false: phlebitis limits veins available for future therapy

A

true

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9
Q

3 sites of intramuscular administration and max volumes

A

deltoid muscle - 2 mL
thigh - 5 mL
gluteal muscle - 5 mL

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10
Q

subcutaneous administration usually does not exceed ___ mL

A

1.5 mL

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11
Q

which has slower absorption?

a. subQ
b. IM

A

a. subQ

(due to lower vascularization of the tissue)

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12
Q

infusion by subcutaneous route is called ?

A

hypodermoclysis

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13
Q

two intra-spinal routes of administration

A

intrathecal (into the subarachnoid space and CSF)
epidural (into space between the dura mater and the vertebral canal i.e. epidural space)

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14
Q

true or false: meds have higher potency with intrathecal administration compared to epidural

A

true

(no membranes/dura to cross; drug goes straight into CSF)

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15
Q

3 special care rules for intra-spinal

A
  1. cannot get away with not being isotonic
  2. cannot get away with not having physiological pH (7.4)
  3. cannot have preservatives
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16
Q

true or false: IM and SC don’t have an absorption step

A

false

17
Q

true or false: parenteral routes of administration bypass hepatic first-pass metabolism

A

true