Exam 2- Lecture 10 (Radiopharmaceutics)

Question 1

What is radiopharmaceutics?

Answer 1

Radioactive drug used for diagnosis or therapy

Question 2

Do radiopharmaceutics have any pharmacological activity?

Answer 2

no

Question 3

When designing radiopharmaceuticals what do you what to keep in mind?

Answer 3

Easy availability
Short effective half-life
Particle emission
High target to non-target activity ratio
Sterile and pyrogen (substances that cause raise in temp) free
Organ participation

Question 4

What are radionuclides?

Answer 4

Substances that have the varying number of protons and neutrons as compared to stable elements

Question 5

How is an atom identified?

Answer 5

By the number of protons in the nucleus

Question 6

PET (positron emission tomography) what is it?

Answer 6

Emits high quality images to identify cancer and evaluate response to cancer treatment

Question 7

What is radioactive decay? Types?

Answer 7

Refers to the particles that are emitted from nuclei as a result of nuclear instability.

Gamma: strongest of the three
Beta: can penetrate top layer of skin, germinal layer, where new cells are produced
Alpha: weakest of the three and cannot penetrate the skin.