Exam 2 key terms Flashcards

1
Q

Chemical Driving Force:

A

The force exerted on molecules due to a concentration gradient, causing molecules to move from areas of high concentration to low concentration.

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2
Q

Electrical Driving Force:

A

The force exerted by the electrical charge difference across a membrane, influencing the movement of charged ions toward opposite charges.

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3
Q

Electrochemical Driving Force:

A

The combined effect of the chemical and electrical driving forces on ion movement across a membrane

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4
Q

Leak Channel:

A

A type of ion channel that is always open, allowing ions to move freely down their concentration gradient

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5
Q

Ligand-Gated Channel:

A

A type of ion channel that opens in response to the binding of a specific chemical (ligand) to a receptor site.

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6
Q

Voltage-Gated Channel

A

A type of ion channel that opens or closes in response to changes in membrane potential (voltage changes).

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7
Q

Regulation of Ion Movement:

A

The process by which ion channels and pumps control the movement of ions across cell membranes to maintain cellular homeostasis.

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8
Q

Membrane Potential:

A

The difference in electrical charge between the inside and outside of a cell, measured across the cell membrane.

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9
Q

Resting Membrane Potential:

A

The membrane potential of a cell when it is not actively sending signals, typically around -70mV for neurons

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10
Q

Na+/K+ Pump

A

A membrane protein that actively transports sodium (Na+) out of the cell and potassium (K+) into the cell, helping maintain resting membrane potential.

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11
Q

Polarization

A

The state of a membrane when there is a difference in charge between the inside and outside of the cell

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12
Q

Depolarization

A

A reduction in the membrane potential, where the inside of the cell becomes less negative relative to the outside, often due to Na+ influx.

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13
Q

Repolarization:

A

The return of the membrane potential to its resting value after depolarization, often due to the efflux of K+ ions.

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14
Q

Hyperpolarization:

A

An increase in membrane potential, where the inside of the cell becomes more negative than the resting potential.

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15
Q

Graded Potential:

A

A small, temporary change in membrane potential that varies in magnitude and dissipates as it travels, typically occurring in dendrites and cell bodies.

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16
Q

Temporal Summation:

A

The summing of postsynaptic potentials generated at the same synapse in rapid succession.

17
Q

Spatial Summation:

A

The summing of postsynaptic potentials generated simultaneously at different synapses on the same neuron.

18
Q

Action Potential

A

A rapid, temporary change in a cell’s membrane potential that occurs when a neuron sends an electrical signal along its axon.

19
Q

Depolarization

A

Membrane potential becomes less negative as Na+ ions rush into the cell.

20
Q

Repolarization:

A

Membrane potential returns toward the resting state as K+ ions exit the cell.

21
Q

Hyperpolarization:

A

The membrane potential becomes more negative than the resting potential, often due to excess K+ leaving the cell before channels close.

22
Q

Membrane is at resting potential, Na+ and K+ channels are closed.

A

Resting State:

23
Q

Na+ channels open, allowing Na+ to flow in, causing the inside of the cell to become more positive

A

Depolarization:

24
Q

Na+ channels close, and K+ channels begin to open.

A

Peak of Action Potential:

25
Q

K+ flows out of the cell, restoring the negative membrane potential.

A

Repolarization:

26
Q

K+ channels stay open too long, causing the membrane to become more negative than the resting potential before returning to rest.

A

Hyperpolarization:

27
Q

A stimulus that is strong enough to depolarize the membrane beyond the threshold, triggering an action potential.

A

Suprathreshold:

28
Q

Gates on ion channels (like Na+ channels) that open in response to depolarization, allowing ions to flow through the membrane.

A

Activation Gates:

29
Q

Gates on ion channels (like Na+ channels) that close after depolarization to prevent further ion flow and help end the action potential.

A

Inactivation Gates:

30
Q

The period during an action potential when no new action potential can be initiated, no matter the strength of the stimulus, because Na+ channels are inactivated.

A

Absolute Refractory Period:

31
Q

The period after the absolute refractory period when a new action potential can be triggered, but only by a stronger-than-usual stimulus, as the membrane is hyperpolarized.

A

Relative Refractory Period:

32
Q

A condition where there is an abnormally low concentration of potassium (K+) in the blood, leading to muscle weakness and potentially affecting heart function.

A

Hypokalemia:

33
Q

A condition characterized by an abnormally high concentration of potassium (K+) in the blood, which can affect the excitability of neurons and muscles.

A

Hyperkalemia:

34
Q
A