Exam 2 - IV Infusion Flashcards
1
Q
IV Infusion
A
administers drug IV at a controlled rate
2
Q
How does IV infusion differ from IV bolus?
A
the concentration of drug in the inlet is not zero
3
Q
Conservation of mass
A
Rate of change of drug mass = rate of drug entry - rate of drug exit
4
Q
Which variables of an IV inufsion are constant?
A
- R (infusion rate)
- V (compartment volume)
- Q (flow rate in/out)
- Cp0 (initial drug concentration at time 0)
5
Q
Units of R (infusion rate)
A
mass/time
6
Q
Which variable determines the rate at which drug concentration increases?
A
k (elimination rate constant)
7
Q
Maximum Cp value
A
R/CL
8
Q
Steady state Cp value
A
R/CL
9
Q
Loading dose
A
Used to reach the desired Cp more quickly
10
Q
Cp equation for IV infusion
A
Cp = (R/CL)(1 - e^(-kt))
11
Q
R vs K
A
R = the infusion rate K = the elimination rate
