Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

OU Immunology > Exam 2 Inflammation Drugs > Flashcards

Exam 2 Inflammation Drugs Flashcards

1
Q

COX inhibitors

A

ASA, IBP, naproxen, indomethacin, celecoxib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

5-Lipoxygenase inhibitors

A

zileuton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

zileuton

A

5-Lipoxygenase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Leukotriene Receptor Antagonists

A

montelukast (Singulair), zafirlukast (Accolate)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

montelukast, Singulair

A

Leukotriene Receptor Antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

zafirlukast, Accolate

A

Leukotriene Receptor Antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PLA2 inhibitors

A

Corticosteroids: Hydrocortisone, dexamethasone, prednisone,…

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Corticosteroids

A

PLA2 inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cytokine inhibitors

A
  • Anakinra (Kineret)
  • Etanercept (Enbrel)
  • Infliximab (Remicade)
  • Adalimumab (Humira)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Anakinra (Kineret)

A
  • recombinant IL-1RA (Receptor Antagonist); blocks IL-1 binding
  • treat: RA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Etanercept (Enbrel)

A
  • fusion protein consisting of TNF receptors linked to immunoglobulin - blocks TNFa binding
  • treat: RA, psoriasis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Infliximab (Remicade)

A
  • anti-TNFa antibody that blocks TNFa binding

- treat: RA, Chrohn’s Disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Adalimumab (Humira)

A
  • fully human anti-TNFa antibody that blocks TNFa binding

- treat: RA, psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

IgE inhibitor

A

Omalizumab (Xolair)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Omalizumab (Xolair)

A

humanized monoclonal antibody that binds to and blocks IgE – treatment of allergy-related asthma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Define antihistamines

A

target histamine receptors; inhibit histamine binding; ex. Cimetidine

17
Q

Selective Adhesion-Molecule (SAM) Inhibitors

A

Natalizumab (Tysabri)

18
Q

Natalizumab (Tysabri)

A

humanized monoclonal antibody against VLA-4 (integrin-a4) which is present on leukocytes and mediates binding to VCAM-1 on inflamed endothelium and other receptors necessary for leukocyte migration. – used in treatment of MS and Chrohn’s

19
Q

Methotrexate

A

General immunosuppressant; inhibits DNA synthesis and therefore inhibits cell growth.

OU Immunology (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions