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Pharm II > Exam 2- Drug Class General > Flashcards

Exam 2- Drug Class General Flashcards

1
Q

What drug class is acetazolamide?

A

CA inhibitor (short-term diuretic)

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2
Q

What drug class is dorzolamide?

A

CA inhibitor (short-term diuretic)

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3
Q

What drug class is brinzolamide?

A

CA inhibitor (short-term diuretic)

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4
Q

What drug class is furosemide?

A

Loop diuretic

Inhibit NKCC2 in thick ascending limb of LOH

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5
Q

What drug class is ethacrynic?

A

Loop diuretic

Inhibit NKCC2 in thick ascending limb of LOH

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6
Q

What drug class is metolazone?

A

Thiazides diuretic

Inhibit NaCl in early distal tubule

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7
Q

What drug class is indapamide?

A

Thiazides diuretic
Inhibit NaCl in early distal tubule

Excreted by biliary system, useful for pts with renal insufficiency
Does not increase lipids
Pronounced vasodilation

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8
Q

What drug class is spironlactone?

A

Aldosterone antagonist

Competitive inhibitor of aldosterone

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9
Q

What drug class is eplerenone?

A

Aldosterone antagonist

Selective aldosterone receptor antagonist

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10
Q

What drug class is Amiloride?

A

Direct inhibitor of Na influx

Inhibits Na/K exchange independently of aldosterone

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11
Q

What drug class is mannitol?

A

Osmotic diuretic

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12
Q

What drug class is isosorbide?

A

Osmotic diuretic

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13
Q

What drug class is glycerin?

A

Osmotic diuretic

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14
Q

What drug class is urea?

A

Osmotic diuretic

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15
Q

What drug class is desmopressin?

A

ADH agonist

Activates V2 receptors (central DI)

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16
Q

What drug class is conivaptan?

A

ADH antagonist

Non peptide V1a and V2 receptor antagonist (SIADH)

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17
Q

What drug class is tolvaptan?

A

ADH antagonist

Non peptide V2 receptor antagonist

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18
Q

What type of drug is enalapril?

A

ACEI

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19
Q

What drug class is losartan?

A

ARB

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20
Q

What drug class is sacubitril/Valsartan?

A

ARNI

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21
Q

What type of drug is dobutamine?

A

Sympathomimetic

Selective B1 agonist

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22
Q

What drug class is dopamine?

A

Sympathomimetic
Low dose D1
Mod dose B1
High dose A

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23
Q

What drug class is digoxin?

A

Digitalis

Inhibit Na/K pump

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24
Q

What type of drug is clonidine?

A

Centrally acting sympatholytic

Stimulate medically A2 receptors

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25
What drug class is methylodopa?
Centrally acting sympatholytics Stimulate medullary A2 receptors? Safe in pregnancy
26
What drug class is prazosin?
A1 agonist
27
What drug class is labetalol?
Combined A1 and b blocker | Safe in pregnancy
28
What drug class is carvediol?
Combined A1 and b blocker
29
What drug class is hydralazine?
Vasodilator (arteries) | Safe in pregnancy
30
What drug class is sodium nitroprusside?
Vasodilator (arteries and veins) and Nitrate/Nitrite
31
What drug class is fenoldapam?
D1 agonist (vasodilates arteries)
32
What drug class are Nifedipine is Amlodipine?
CCB More effect on vessels (more likely to produce reflex tachycardia) Nifedipine is safe in pregnancy
33
What drug class is diltiazem?
CCB
34
What drug class is verapamil?
CCB | More effect on cardiac tissue
35
What drug class is ranolazine?
Partial fatty acid oxidation inhibitor | Last choice for tx of angina
36
What drug class is silfenafil (viagra)?
PDE5 inhibitor
37
What drug class is vardenafil?
PDE5 inhibitor (more selective, fastest acting)
38
What drug class is tadalafil?
PDE5 inhibitor (more selective, longest acting)
39
What drug class are statins?
HMG-Co reductive inhibitors (decrease LDL)
40
What drug class is cholestyramine?
Bile acid binding resins (safe in pregnancy)
41
What drug class is niacin?
Drugs that impair synthesis of lipoproteins (increase HDL)
42
What drug class is gemfibrozil?
Fibrin acid derivative (decreases triglycerides) | PPAR-a ligand that up-regulates lipoprotein lipase
43
What drug class is ezetimibe?
Inhibitor of cholesterol absorption (only used in combo with a statin, doesn’t decrease CV mortality)
44
What drug class is alirocumab?
PCSK9 inhibitor
45
What drug class is evolocumab?
PCSK9 inhibitor
46
What type of drug is quinidine?
Class IA anti-arrhythmic | Binds to activated Na channels
47
What type of drug is procainamide?
Class IA anti-arrhythmic | Binds to activated Na channels
48
What drug class is lidocaine?
Class IB anti-arrhythmic | Blocks inactivated Na channels
49
What drug class is flecainide?
Class IC anti-arrhythmic | Blocks all Na channels
50
What drug class is propanolol (in regards to anti-arrhythmic)?
Class II anti-arrhythmic | Non specific b blocker
51
What drug class is metoprolol (in regards to anti-arrhythmic)
Class II anti-arrhythmic | B1 blocker
52
What drug class is esmolol (in regards to anti-arrhythmic)?
Class II anti-arrhythmic | B1 blocker
53
What drug class is amidarone?
Class III anti-arrhythmic | Blacks K channels
54
What drug class is sotalol?
Class III anti-arrhythmic | Blocks K channels
55
What is adenosine used for?
DOC for acute PSVT and WCW | Effective for only reentry arrhythmias
56
What is magnesium used for?
DOC for tosades de pointes
57
What drug class is enoxaprin?
LMWH (inhibits Xa)
58
What drug class is fondaparnux?
LMWH (inhibits Xa)
59
What drug class is dabigatran?
Oral direct thrombin inhibitor
60
What drug class is rivaroxaban?
Oral direct factor Xa inhibitor
61
What drug class is apixaban?
Oral direct factor Xa inhibitor
62
What drug class is heparin?
HMWH (binds to antithrombin III, causing it to inactivate clotting factors, mainly Xa thrombin)
63
What drug class is warfarin?
Clotting factor synthesis inhibitor | Inhibits reduction of vitamin K and interferes with synthesis of II, VII, IX, X and protein C/S
64
What drug class is alteplase or tPA?
Fibrinolytic agent | Converts plasminogen to plasmin
65
What drug class is aminocaprotic acid?
Antifibrolytics | Inhibits plasminogen activation
66
What drug class is tranexamic acid?
Antifibrinolytic | Inhibits plasminogen activation
67
What drug class is aspirin?
Antiplatelet | Irreversible COX inhibitor
68
What drug class is clopidogrel?
Antiplatelet | Irreversibly blocks the ADP receptor on platelets
69
What drug class is ticagrelor?
Antiplatelet | Irreversibly blocks the ADP receptor on platelets
70
What drug class is abciximab?
Antiplatelet | Prevents GP IIb/IIIa from binding fibrinogen

Pharm II (10 decks)

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