Exam 2 Content Flashcards

1
Q

what is the primary function of the digestive system

A

to break down food into smaller units of absorbable nutrients

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2
Q

what is the alimentary canal

A

structure that forms long tube used to break down food

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3
Q

how long does it take to go from ingestion to defecation?

A

24 hours

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4
Q

what organs participate in digestive process without food passing through

A

liver
pancreas
gallbladder
salivary glands

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5
Q

what are the purpose of the accessory digestive organs

A

to digest without pass through of food

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6
Q

what is ingestion

A

put food into mouth

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7
Q

what is propulsion

A

movement of food through canal

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8
Q

is swallowing voluntary or involuntary?

A

voluntary

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9
Q

is peristalsis involuntary or voluntary

A

involuntary

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10
Q

what is mechanical digestion

A

physical breakdown of food
(ie. chewing churning segmentation)

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11
Q

define peristalsis

A

an organized contraction of relaxation and smooth muscle layers that propels food through the alimentary canal in one direction

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12
Q

define segmentation

A

contractions of smooth muscle move chyme back and forth within a canal to allow mixing and further breakdown

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13
Q

what is chemical digestion

A

enzymes and chemicals break down food

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14
Q

what is absorption

A

particles are transported from canal into blood or lymph capillaries

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15
Q

Defection

A

Indigestible products are eliminated as feces

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16
Q

what is the inner canal of the alimentary canal called?

A

the lumen

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17
Q

are there consistent layers of tissues that form the alimentary canal?

A

yes

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18
Q

order the layers from lumen to outer layer

A

Lumen, Mucosa, Submucosa, Muscularis externa, Serosa

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19
Q

what is the submucosa

A

support layer

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20
Q

what is the mucosa

A

lines the lumen

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21
Q

what is the muscularis externa

A

muscle layer

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22
Q

Serosa

A

the outer surface

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23
Q

what is found in the lumen

A

the food that has been consumed

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24
Q

in which of the 4 main layers of the alimentary canal would you expect to find an epithelium?

A

Mucosa and serosa only

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25
How many sublayers does the mucosa have?
3
26
What are the 3 sublayers of the Mucosa?
Epithelium, Lamina Propria, Muscularis Mucosa
27
What does the sublayer of epithelium do?
Mucus production, absorbtion and protection , contains digestive glands
28
What does the Lamina Propria do?
Capillary rich, loose areolar with MALT
29
What is MALT
mucosa associated lymphoid tissue (provides defense)
30
Muscularis mucosa
thin layer of smooth muscle localized movements
31
What is the submucosa
similar to loose areolar ct as in provide support highly vascularized glands connecting to lumen may project to submucosa
32
Submucosal nerve plexus
control of muscle cells, glandular secretions
33
Muscularis Externa
2 layers of smooth muscle circular and longitudinal
34
What is circular muscle
inner layer typically squeeze tubes
35
What is longgitudinal muscle
outer layer, typically shortens tube peristalsis and segmentation
36
Myenteric nerve plexus
Inntervates muscularis externa is in between longitudinal and circular
37
Enteric Nervous System
controls smooth muscle and glands of alimentary canal
38
What is considered the Enteric Nervous System
the brain in the gut has many neurons as entire spinal cord
39
Serosa location?
Found around organs within abdominal cavity
40
What is the serosa membrane made of?
Simple squamous and thin loose areolar
41
Another name for the serosa is
viceral peritoneum
42
Alimentary canal linings always have serosae as outer layer?
no
43
What is the esophagus lined with?
adventitia ( a fibrous CT)
44
what is the enteric nervous system
located entirely within the wall of the alimentary canal with nerve plexuses that allow for localized response within visceral organs
45
Myenteric nerve plexus
controls peristalsis and segmentation within muscularis exerna
46
submucosal nerve plexus
controls sectretions of glands and muscularis mucosa contractions within submucosa.
47
What is included in the oral cavity?
Mouth, ingestion, mechanical digestion, chemical digestion
48
what is chemical digestion made of?
mixed with saliva that contains amylase, starts chemical breakdown of carbs
49
what kind of epithelium would be found lining the oral cavity
stratified squamous
50
why would you find stratified squamous in the oral cavity?
The oral cavity is a continuation of skin, food is abrasive, and food and drink temperatures vary.
51
what is the anatomy of the mouth?
Thin submucosa layer anchored directly to underlying bone with no muscularis externa or serosa
52
What are the lips made of?
margin between skin and oral cavity, poorly keratinized, no eccrine or sebaceous glands
53
which lip is more likely to get non-melanoma skin cancer?
lower lip
54
what is the tounge?
accessory digestive organ, superior surface is what you see, moves food and helps to mix to form bolus
55
is the tounge keritanized?
yes
56
what is the filiform papille?
rough surface containing keratin
57
Fungiform and circumvallate papillae have what?
taste buds
58
Lingual Frenulum
fold of the mucosa layer connects tounge the floor of the mouth
59
"Tounge Tie" or ankyloglossia
If lingual frenulum extends too far forward, makes tip of tounge hard to speak
60
which layer of the alimentary canal lines the lumen of a digestive organ
mucosa
61
what are the Salivary glands
accessory digestive organ that is an exocrine gland produces saliva
62
saliva purpose
moistens mouth, dissolves food allowing taste, contains digestive enzymes
63
what digestive enzymes are in saliva
amylase (breakdowns carbs) and lipase(begins digestion of fats)
64
What cell types are in saliva
serous cells secrete digestive enzymes and mucous cells secret mucous
65
What is the Parotid gland and duct
largest salivary gland contains serous cells that produce watery enzyme secretion near 2nd upper molar
66
submandibular gland and duct
approx. equal amounts of serous and mucous cells, ducts open lateral to lingual frenulum
67
sublingual glands and ducts
mostly mucous cells and several ducts empty below tounge
68
what process of digestion does not typicall take place in the oral cavity
absorption of nutrients
69
What are teeth / purpose
accessory to digestive organs involved in chewing
70
what is heterodont dentition
different shapes of teeth for different jobs
71
Deciduous Teeth
"baby teeth" 20 erupt typically between ages 6 months and 6 years
72
Permanent teeth
32 total teeth
73
types of permenant teeth
incisors, canines, premolars, molars
74
what do incisors do
4 pairs good for cutting and shearing food
75
what do canines do
2 pairs surface good for holding and tearing
76
premolars
4 pairs rounded broad surface good for grinding
77
what do molar do
6 pairs
78
what are the regions of the tooth?
crown(part above gumline) neck(narrow contained within gum tissue) root(contained within bone)
79
tooth anatomy is what?
pulp and detin
80
what is pulp in the tooth?
loose areolar ct blood vessels and nerves provide nutrients and sensation to tooth odontoblast create dentin
81
what is dentin in the tooth?
collagen and mineral that form the bulk of the tooth deep to enamel has radial striations that can contibute to tooth sensitivity.
81
82
what is enamal
hardes subsance in the body 99% calcium salts
83
cement
calcified ct that covers root
84
Periodontal ligament
dense t that attaches cement of tooth to bony socket
85
what type of joint are periodontal ligaments
gomphosis
86
cavities are what (caries)
demineralization of enamel and dentin beginning with dental plaque
87
what is dental plaque
biofilm made of sugars and produce acids
88
what is a root canal
pulp is drilled out and tooth is now dead cavity is sterilized and fill tooth capped to strengthen it
89
what are joints classified on
mobility
90
what are the three kinds of joint mobility
synarthrosis amphiarthrosis and diarthrosis
91
What are firbous joints
no joint cavity dense regular ct connecting bones
92
what are catilangious joints
no joint cavity cartilage connects bones
92
what are synovial joints
there is a joint cavity ligaments and articular capsule connect bone end of bone covered in cartilage
93
what is a firbous structure made of
synathrotic and connected with short dense regular ct
93
What do fibrous joints sutures do
allow for skull growth
93
what do firbous joints syndesmoses do?
with a ligament amphiarthrotic desnse regular ct longer than sutures between long bones
93
where are firbous joints syndesmoses found?
between long bones
94
what are firbous joints syndesmoses examples?
ligament between distal tibia and distal fibula interosseous membrane between radius and ulna
94
what are fibrous joints gomphoses
peg in socket joint, synarthrotic periodontal ligaments attatch to tooth this way
94
whatt is Cartilaginous Joints Synchondroses
bones united by hyaline cartilage, synarthrotic
94
what is a Cartilaginous Joints Synchondroses example
epiphyseal plates joints between first rib and sternum
95
what is a cartilagious joint symphyses
amphiarthrotic bones united by firbocartilage pad
96
what is an example of cartilagious joint symphyses
intervertebral discs pubic symphysis
97
what are Synovial joints
diarthrotic= freely moveable have ligaments joint cavities and articular capsule
98
what is a ligament
dense regular ct that can be within external to joint capsule
99
what is a joint cavity
potential space with a small amount of synovial fluid
100
what is the articular capsule
outer fibrous layer and inner synovial membrane (lubricant within capsule) dense irregular ct (periostuem)
101
what is synovial fluid
vicous slippery movement of joint found in articular cartilage and cavity nourishes the avascular articular cartilage
102
are there nerves in synovial joints
yes rich supply
103
is there blood supply in the synovial joints
yes, supply synovial membrane
104
do synovial joints have an artcular disc
yes, some do
105
what is an articular disc
helps improve fit made of fibrocartilage
106
what is a labrum
increases stability in joint
107
what is the synovial joint bursae
closed fibous sac lined with synovial membrane filled with fluid that reduces friction with ligaments and bone overlap
108
what is a tendon sheath
elongated bursa that wraps around tendonds in high friction areas
109
are all synovial joints diarthrotic
yes
110
types of synovial joints
nonaxial - not around axisis for movement uniaxial - moves around 1 axsis biaxial - moves around 2 multiaxial - moves around 3 or more
111
nonaxial def.
can move in many directions on one plane
112
uniaxial
moves only around 1 axsis
113
biaxial
moves around 2 axes
114
multi axial
moves around 3 or more axsis
115
plane joint
synovial nonaxial gliding movement
116
hinge joints
synovial uniaxial flexion and extention
117
pivot joints
uniaxial rotational movement
118
condylar joint
synovial biaxial flexion and extension abduction/adduction in knuckles head motion
119
saddle joint
synovial biaxial flexion and extension abduction/adduction in thumbs
120
ball in socket joint
synovial multiaxial flexion and extension abduction/adduction rotation shoulder
121
is the fibula part of the kee
no
122
the knee is made of what
2 joints share one capsule and cavity femoropatellar tibiofemoral
123
what is the fermoropatellar
between patella and femur made of plane joint
124
what is the tibiofemoral joint
between tiba and femur must withstand body weight
125
tibiofemoral joint movement
in two axes weight bearing joint in stability and mobility (ligaments and tendons and menisci) meet at angle
126
tibiofemoral joint mobility
structure around all flexibilty for changes on surface and adapt to walking vs running
127
tibiofemoral joint has 2 layers. what are they?
firbrous outer layer and innter synovial membrane
128
what do ligaments do
provide support and strength
129
what is the pharynx
connects the oral cavity to esophagus and nasal cavity
130
how many parts of the pharynx are related to digestion
2
131
Oropharynx
behind oral cavity made of stratified squamous
132
laryngopharynx
inferior to oropharynx made of stratified squamous
133
what has a skeletal muscle for swallowing
muscularis externa
134
Order from top to bottom on model : nasopharynx oropharynx laryngopharynx esophagus
nasopharynx oropharynx laryngopharynx esophagus
135
what is the esophagus
connects pharynx to stomach made of stratified squamous
136
what do the mucus glands in submucosa do
secrete mucous to allow food to pass through
137
What is the upper third of esophagus made of
skeletal muscle
138
What is the middle third of esophagus made of
mix of skeletal and smooth muscle
139
What is the lower third of esophagus made of
smooth muscle
140
What is a hiatal hernia
the superior part of the stomach pushed through esophageal hiatus following weakening of diaphram muscles
141
what is Barretts esophagus
due to persistant exposure of acidic stomach contents can result in ulcers
142
what is the outer layer of the esophagus called
adventitia
143
how long does food spend in the stomach
about 4 hours being churned into chyme
144
does any absorption take place here in the stomach
yes, a small amount limited to water alchohol and drugs like asprin
145
what is the lining of the stomach made of
simple columnar epithelium made of cells that produce mucous gastric pits that open to glands
146
What is rugae(wrinkles)
folds of the mucosa that increase surface area allowing expansion of stomach
147
What are the reigions of the stomach
cardia fundus body pyloric antrum pylorus with pyloric sphincter
148
What is a sphincter
thicken region of muscularis externa
149
Muscularis externa has extra layer
longitudinal circular oblique(innermost)
150
What layers does the muscosa include?
Surface epithelium lamnia propria muscularis mucosae gastric pit gastric gland
151
what layers does the submucosa include
contains submucosal plexus
152
what does the musularis externa include
oblique layer circular layer longitudinal layer
153
What layer follows the musularis externa
serosa and stomach wall
154
what do the mucous neck cells do
secrete mucus function unknown
155
what do gastric pits do
epithelium cups down meet gland
156
what do gastric glands do
connets lumen through pit contain specilized cells
157
what cells are included in gastric glands
parietal: produce and secrete two products HCI and GIF Chief: produce and secrete pepsinogen and gastric lipase fat digestion
158
What does pepsin do
breaks down protiens in food using pepsinogen and HCI
159
What do enteroendocrine cells do
release hormones
160
what do undifferentiated stem cells do
found at junction between gastric pit and gland replaced every 3-7days
161
what is gastrin
hormose released by enteroendocrine cells used to stimulate parietal cells
162
what is the small intestine
longest segment of canal at 16 ft
163
what is the small intestine made of
simple columnar cells site of most absorption and chemical digestion chyme moves through via peristalsis
163
what is the jejunum
middle part of small intestine most absorption occurs here
164
what is the duodenum
the shortest segment of small instestine recieve a number of substances ( enzymes chyme and bile)
165
what is he illeum
longest part of small intestine absorption occurs here as well
166
What are the small intestine wall layers
all typical layers of alimentary canal occur in small intestine
167
Does the small intestine have a small or large surface area?
large, to increase absorption
168
what do circular folds do
increase surface area and force chyme to spiral
169
what do villi do
made of absorptive cells and have blood capillaries have lacteals that absorb fat
170
what do microvilli do
called brush border
171
is the lamina propria vascular or non vascular
highly vascular
172
what are the specialized cells of the small intestine
Absorptive enterocytes and goblet cells
173
What do Absorptive enterocytes do
lots of mitochondria absorption of nutrients abundant ER assemble lipids into chylomicrons
174
what do goblet cells do
secrete mucus
175
order process of producing pepsin
food enters stomach release of gastrin into blood gastrin stimulates release of pepsinogen from chief cells gastrin stimulates release of HCL pepsinogen and HCl from pepsin pepsin digests protien
176
what are intestinal crypts
epithelial cells that produce inestinal juice undifferentiated epithelilal cells (stem cells)
177
what is chylomicron
help transport hydrophobic molecules in a hydrophillic enviroment
178
what are paneth cells
at base of crypt secrete enzymes that kill unwanted bacteria
179
what are duodenal glands
ducts that open into intestinal crypts found ONLY IN SUBMUCOSA OF DUODENUM help neutralize chyme
180
what is MALT and where is it located
mucosa associated lymphoid tissue in mucosal layer of small intestine
181
what is Aggregated lymphoid nodules (Peyer’s patches)
located in submucosa of ileum
182
what does the duodenum do
stomach contributes chyme gallbladder adds bile pancreases produces enzymes and juice hepatopancreatic sphincter is final control valve
183
what does chyme do when entering stomach when fats are present
release of CCK breakdown fat for absoprtion
184
what does chyme do when entering stomach when acids are present
release of secretin neutralize acids
185
what is the hepatopancreatic sphincter
the final control valve in duodenum
186
What is the epiploic appendages
membrane covered fat filled pouches on outside
187
What is teniae coli
longitudinal strips of smooth msucle cause sacs
188
what is haustra
saclike structures
189
what are lleocecal valve
connects the ileum to cecum
190
what is the cecum
vermiform appendix off of cecum, stores benifical bacteria
191
what are the four parts of the colon
ascending transverse decending sigmoid
192
what type of epithelium would you expect to find in large intestine
simple columnar
193
are there circular folds in the large intestine
no
194
are there villi in the large intestine
no
195
what cells are in the large intestine
colonocytes that absorb water and electrolytes
196
are there goblet cells in the large intestine
yes, alot
197
intestinal crypts replace when
every 7 days
198
what is the rectum
connects the sigmoid colon to anal canal
199
rectal valves
folds that prevent feces being passed with gas
200
what is the anal canal epithelium
transitions into stratified squamous
201
what is the external anal sphincter
skeletal muscle voluntary control
202
what is the internal anal sphincter
smooth muscle involuntary control
203
is skeletal muscle voluntary or involuntary
voluntary
204
is smooth muscle voluntary or involuntary control
involuntary
205
what are hemorrhoids
varicose veins that swell caused by excessive straining
206
Where do you think the majority of absorbed nutrients from the alimentary canal end up?
Within veins so it can travel to the liver for processing
207
what are the excessive organs of digestion in the abdominal cavity
liver gallbladder pancreas
208
what does the liver do
produce bile process blood coming from stomach and intestines
209
where is the bile stored before it is released
stored in gallbladder released into duodenum
210
how many lobes are in the liver
4
211
what are the lobes of the liver
right left quadrate caudate
212
what is the hepatic portal vein
gather blood from digestive organs and transport to liver
213
what is the hepatic artery proper
provide oxygen rich blood to liver
214
what is the hepatic portal vein
transport nutrient rich blood from stomach and intestine to liver
215
what is the inferior vena cava
removes blood from liver after being processed
216
wha do portal triads include
bile duct portal venule portal arteriole
216
order these in process of digestion: gallbladder common hepatic duct blood entering bile duct
blood entering common hepatic duct bile duct gallbladder
216
what are liver cells shaped like
hexagons called lobules
217
what is the hepatic portal vein high and low in
low on oxygen high in nutrients
218
is the hepatic portal artery the same as vein
no, opposite
219
what are liver sinusoids
large capillaries between plates of hepatocytes
220
what are central veins job
to drain blood out
221
what are stellate macrophages
hepatic macrphages move through sinusoids destroy microorganisms
222
where does bile go from the hepatocytes
to the bile canaliculus then to bile ducts
223
Within which structures of the liver is the arteriole blood and venous blood mixing?
Sinusoid
224
how many capillary beds does blood enter before going back to the heart from the portal system
2
225
what are gallstones
formed of cholesterol that precipitates out of bile while stored in gallbladder
226
What is controlling the release of bile into the duodenum?
Cholecystokinin released by the enteroendocrine cells of the duodenum signal the sphincter to open
227
how does bile get released
a sphincter controls release of bile in the duodenum
228
function of pancreas
juices transported in main duct and released by sphincter
229
what cells are in pancreas
acinar cells produce and secrete pancreatic enzyme
230
what hormone controls pancreatic release
secretin
231
two cells in pancreas are called
beta and alpha
232
alpha cells make
glucagon
233
beta cells make what
insulin
234
Peritoneum can be
viceral parietal
235
what is the mesentery
double sided membrane that suspends organs within cavity contains blood vessels nerves and fat
236
Which cell found in the epithelium of the alimentary canal produces GIF (gastric intrinsic factor) to help with the absorption of Vitamin B12 for red blood cell formation?
Parietal cells of the stomach
237
what are another product of parietal cells
hydrochloric acid
238
what are ulceres
erosions of mucosa in duodenum or pyloric region of stomach due to bacterium
239
Inflammatory bowl disease has how many types and what are they
2 Crohns disease ulcertive colitis
240
irritable bowel sydrome is
large intestine cause unknown
241
celiac disease is
auto immune disorder gluten triggers immune response damage villi of small intestine
242
What are the functions of the respiratory system
bring in oxygen remove CO2 sound production smell protection
243
Steps of respiration are
Ventilation Gas Exchange Oxygen
244
Where can gas exchange occur?
Between the air in the lungs and red blood cells and Between the red blood cells and cells of tissues throughout the body
245
What is external respiration
gas exchange between air and red blood cells in the lungs
246
what is internal respiration
Gas exchange between red blood cells and body tissues outside the lungs
247
What are the major organs of the respiratory system categorized by
conducting zone and respiratory zone
248
conducting zone does what
transport air filter out dust humidity and warm incoming air
249
respiratory zone does what
site of gas exchange in the lungs
250
what structures are in the conducting zone (9)
* Nasal cavity * Pharynx * Larynx * Trachea * Main bronchi * Lobar bronchi * Segmental bronchi * Bronchioles * Terminal bronchioles
251
what parts are involved in the respiratory zone(4)
Respiratory bronchioles * Alveolar ducts * Alveoli * Cluster of alveoli = alveolar sac
252
The visceral and parietal pleura are considered:
Serous membranes
253
what is the pleurae?
serous membranes with fluid in between to allow lungs to inflate when breathing
254
pleural effusion is what
accumulation of fluid in the pleural cavity
255
Pnemothorax is what
when the negative pressure is broken between lungs and a lungs collapses
256
what are the functions of the nose
filter and warm air smell speech
257
what structures support external nose
nasal bones hyaline cartilage dense CT
258
what is the olfactory mucosa
near roof houses receptors for smell
259
what is respiratory mucosa
lines most of the passage way from nasal cavity to lungs
260
what is the respiratory mucosa made of
Pseudostratified ciliated columnar epithelium
261
does the respiratory mucosa have lamnia propria
yes
262
how much mucous to goblet cells produce everyday
1 quart
263
what is the mucociliary escalator
cilia with moving sheets of mucous can be slowed down by cooler air
264
External nares and vestibule are
the opening to nasal cavity lined with hairs
265
what is the nasal conchae
bony ridges that create air turbulence
266
olfactory receptor cells do what
pass through cribriform plate in to olfactory mucosa
267
where does the nasal cavity end
at the posterior nasal aperture
268
Paranasal sinuses are what
air filled cavity in bone
269
what doe the paranasal sinuses do
lighten skull single opening to nasal cavity warm and moisten air
270
what are the bones named for
named for bones found in frontal, ethmoid sphenoid maxillary
271
what is the nasal meatus
opening for sinus into nasal cavity superior middle inferior
272
what is the nasal meatus
a sinus infection inflammation of epithelium caused by bacteria or virus
273
Deviated septum
cartilage becomes misaligned
274
nasal septum
bone and cartilage that separates cavity in half
275
Which division(s) of the pharynx must handle the passage of food, liquid, and air?
Both oropharynx and laryngopharynx
276
what type of epithelium is in the pharynx
stratified squamous and pseudo-stratified columnar
277
what does the nasopharynx include
pharyngeal tonsils phayngotumpanic tube
278
what closes off he nasopharynx
uvula
279
what is included in the oropharynx
palatine and lingual tonsils tonsilits occurs here
280
what is tonsillitis
inflammation of palatine tonsils
281
laryngopharynx does what
Connects pharynx with openings to larynx (air) and esophagus (food)
282
what structures are in the larynx
epiglottis thyroid cartilage cricoid cartilage arytenoid cartilage
283
what does the epiglottis do
covers larynx when swallowing made of elastic cartilage
284
what does the thyroid cartilage do
hyaline attatchment site for vocal folds
285
what does cricoid cartilage do
hylaine
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arytenoid cartilage
hyaline anchors vocal folds posteriorly
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what are vocal folds
true vocal cords vibrate when air passes long in males short in females
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vestibular folds
false vocal cords support vocal folds
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what do vocal folds include
* Rima glottidis = space between open vocal folds * Glottis = vocal folds + rima glottidis
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Which anatomical structure or feature of the respiratory system plays a large role in the loudness of your voice?
The volume of the lungs
291
what is laryngitis
inflammation of vocal cords that prevents proper vibration
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what is the trachea
flexible but strong connnection to lungs
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what is the trachea made out of
Pseudostratified ciliated columnar epithelium * With goblet cells
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what are the rings of the trachea made of
hyaline cartalige and joined by fibro elastic ct
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how many rings are in the trachea
16-20
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what does smoking do to cilia
paralyze or destroyed by toxins
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what is the cross section of the trachea made of
* Mucous membrane * Submucosa with seromucous glands * Hyaline cartilage * Adventitia covering * Trachealis muscle * Smooth muscle that completes posterior of trachea
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what is the carina
last ring in trachea intiate cough reflex
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what is the bronchial tree made of
Main (primary) bronchi (1 per lung) * Lobar (secondary) bronchi (1 per lobe) * Segmental (tertiary) bronchi (1 per bronchopulmonary segment) * Bronchioles = branches of tertiary, lack cartilage, <1mm diameter
300
what is the main bronchi
cartilage rings are replaced by irregular plates right is wider
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how many lobes does the right lung have
3
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how many lobes does the left lung have
2
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what is the segmental bronchi
segments that function indenpendtly of one another
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are there smooth muscles in the bronchus
yes
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how many phases does asthma have
2 early and late
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what is the early phase
Early phase * Allergens, cold air, etc. cause mast cells to release inflammatory chemicals (histamine) * Cause contraction of bronchial smooth muscle = bronchoconstriction * Increase in mucus secretion in airways
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what is the late phase
* Late phase (after several hours) * Different white blood cells accumulate in bronchi and bronchioles and release inflammatory chemicals → damage mucosa, causing increased release of mucus * Further increase bronchoconstriction
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What are the treatments for bronchitis
Bronchodilators (counter bronchoconstriction) * Anti-inflammatories (counter inflammation)
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what is the respiratory zone
location of exernal gas exchange
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what is the aveolar sac
cluster of alveoli on duct increase volume adn surface area
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Gas exchange occurs across the respiratory membrane in the lungs. Which structures would you expect to see making up this membrane?
Epithelium of capillary wall Epithelium of alveolar wall Basement membrane
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where does gas exchange occur
across the respitory membrane
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what cell types are in the alveoli and respiratory membrane
Type I cells (simple squamous; extremely thin) * Type II cells (cuboidal) * Secrete surfactant which decreases surface tension; allows alveoli to re-inflate more easily * Macrophages * Phagocytize inhaled particles * Move to bronchi where cilia sweep them up and out * Alveolar pores * Equalize pressure between alveol
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what is a lobule
made of 1 larger bronchiole and all its branches * Hexagonal shape * Size of pencil eraser to a penny
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what is the stroma
elastic ct that surrounds lobules
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As the thoracic cavity expands, why does air rush into the lungs?
The air pressure within the lungs decreases as the cavity increases in size
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what is inspiration
diaphram moves inferiorly with contraction thoratic volume decreases
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what is expiration
diaphram moves superiorly thoratic volume decreases
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what is respiratory distress
type 2 cells are not functional collapsed alveoli treated with O2
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what is the primary cause of lung cancer
smoking!
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how does smoking cause damage
cause damage to cilia increase mucous production depress microphages
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how to treat lung cancer
remove diseased tissue
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COPD
air flow in an out of lungs is obstructed
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how many types of COPD are there
2 chronic and emphysema occur together often
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what is emphysema
COPD related to smoking inflammation