exam 2, chapters 26, 27, 28, 29, 30 Flashcards
viruses
very simple, made of DNA or RNA, no cytoplasm
3 types of viruses
RNA, DNA, retroviruses
virus structure
protein sheath or capsid, nucleic acid core
reverse transcriptase
RNA-> DNA, uses the host’s energy to turn RNA into DNA
tissue tropism
inside a host, the virus may only infect specific time
Viral replication
- infect a host cell
- the viral genome tricks the host cell into making viruses
- new viruses leave cells to infect other cells
replication is error-prone=
high rates of mutation
retroviruses
have single-stranded RNA genome that is transcripted to double-stranded DNA, reverse transcriptase
virus classification
taxonomy, genome classifications Baltimore classification, the host they infect, the disease they cause
taxonomy
uses order, family, subfamily, and genus
genome classification, Baltimore classification
are you DNA or RNA virus?
metagenomics
shows different kinds of viruses present
bacteriophages
viruses that can attack bacteria, very very small
lytic cycle
cut, break, delete the bacteria DNA, kill the cell
lysogenic cycle
the virus does not immediately kill the infected cell, it adds itself to its genome
lysogen
bacteria
viral infections
persistent vs. acute
persistent infections
latent or chronic
acute infections
latent or chronic
acute
rapid replication of virus and can lead to sudden symptom onset
HIV
destroying what is used to keep you healthy, acquired immune deficiency syndrome
latent viral infections
no symptoms, viruses that “hide” in the host
latent viral infections can be triggered
due to physiological stimuli (not eating, sleeping well)
prions
“proteinaceous infectious particles”, act like viruses, they misshape other proteins so that they wont function properly
missfolded proteins cuase normal proteins to
misfold, causing disease
viroids
tiny naked molecules of circular RNA, that produce small interfering RNAs and plant growth and development
prokaryotic
oldest, structurally simplest, and most abundant forms of life
prokaryotes fall into two domains
bacteria, archaea
unicellular
most single-celled
cell size
sizes vary tremdously
nucleoid region
DO NOT have a nucleus, not walled off, chromosome is often linear double-stranded DNA
cell division
binary fission, cell splitting
characteristics of prokaryotes
do not perform sexual reproduction, can share genetic material just not through sexual reproduction, no membrane-bounded organelles, flagella-they can move
archaean membrane
glycerol linked to hydrocarbon chains by ether linkages
bacterial membrane
ester linkages, archaea form a monolayer instead of a bilayer
cell wall
peptidoglycan creates a rigid network
gram-positive bacteria
a think, complex network of peptidoglycan, PURPLE
gram-negative bacteria
a think layer of peptidoglycan, 2 plasma membranes, resistant to many antibiotics, PINK/RED
molecular clasification
- amino acid sequences of key proteins
- percent guanine-cytosine content
- gene and RNA sequencing ribosomes
- whole-genome sequencing- problem
3 basic shapes
bacillus, coccus, spirllum
flagella
composed of protein flagellin, involved in locomotion
pili
found in gram-negative bacteria, aid in attachment and conjugation
3 types of sharing genes without reproduction
conjugation, transformation, transduction
conjugation
the physical connection between two bacteria that share plasma
transformation
bacteria dies and another bacteria utilizes its resources
transduction
the virus moves bacteria from one cell to another