Exam 2 - chapter 23 Flashcards
1
Q
hemolytic anemia causes
A
(When RBC destruction occurs in blood)
Genetic
- Sickle cell anemia
- thalassemia s (not enough of alpha or beta chain)
Acquired
- Drugs, toxins, venoms, immunohemolytic anemia → this can develop when a sensitized Rh-mom is carrying Rh+ fetus
2
Q
sickle cell crises
A
Irreversibly Sickled cells (deoxygenated) stick to wall of blood vessel and cause infarctions and ischemias
3
Q
sickle cell crises s/s
A
- Appear at 8-10 weeks of age
- Tachycardia
- Splenomegaly in young ppl, in adult: fibrotic
- Vascular occlusion and infarction → painful and damages tissues and organs (necrosis), strokes