Exam 2, ch9 part2 Flashcards

1
Q

Define Confidence Interval

A

Indicates amount of uncertainty associated with a sample estimate of a population parameter

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2
Q

If CI crosses 1 what it means?

A

Ex: 0.7 - 1.1 crosses 1 and means not significant (no difference between arms of study)

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3
Q

What does CI of 90% mean?

A

Expect 90% of interval estimates to include population parameter

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4
Q

P-value below and above 0.05 means?

A
<0.05= statistically significant difference between groups
>0.05= not a statistically significant difference between groups
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5
Q

Define Relative Risk

A

Ratio of the risk of an event among the exposed to the risk among the unexposed

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6
Q

RR value of 1, below 1, and above 1 mean?

A

RR >1 is risk of the outcome of interest is increased for one group
RR <1 is risk of the outcome of interest is decreased for one group
RR=0 is risk of the outcome of interest is equal between groups

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7
Q

Define Odds Ratio. When used most?

A

Ratio of odds of an event occurring in one group to the odds of an event occurring in another group

Retrospective in case-controlled and studies of harm.

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8
Q

Odds Ratio 1, below 1, above 1?

A

OR=1 exposure does not effect odds of outcome
OR <1 exposure associated with lower odds of outcome
OR >1 exposure associated with higher odds of outcome

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9
Q

Define Hazard Ratio

A

Measure of how often a particular adverse event occurs in one group compared to another group

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10
Q

What is the primary distinguishing characteristic of a hazard ratio?

A

Element of time

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11
Q

What to hazard studies look at?

A

Serious adverse events or death

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12
Q

Hazard Ratio (HR) 1, below 1, above one?

A

HR=1 is equal hazard
HR>1 is greater hazard
HR<1 is lesser hazard

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13
Q

Survival analysis can be used to calculate which ratio?

A

Hazard Ratio

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14
Q

What is Absolute Risk of disease?

A

Risk of developing a disease over a period of time

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15
Q

What does Relative Risk compare?

A

Used to compare risk in two different groups of people

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16
Q

Define Number Needed to Treat (NNT). Accepted number?

A

Number of people needed to be treated on average to have an impact on one person

Accepted=2.5

17
Q

Define Number Needed to Harm (NNH)

A

Number of persons needed to be treated, on average, to produce one of more adverse event(s)

18
Q

Define Number Needed to Screen (NNS)

A

Average number of persons who must undergo a screening test and the ensuing diagnostic and therapeutic procedures in order to prevent one case of the disease of interest.