Exam 1 - Lecture 1 EBP Flashcards
Clinical Expertise, Best Research Evidence, and Patient Values & Preferences are the three parts of what?
Evidence Based Practice
Best available research, knowledge and skill, collaborative patient centered decisions, and context of a giving clinical situation are four key concepts of what?
EBP
When were clinical articles published?
1981
When did EBM begin to appear in the ACP Journal Club?
1991
When did the EBP Working Group publish “The Users guide to Medical Literate” in JAMA?
1993-2000
Define “Outcomes”
Measurable or observable results of illness or treatment
What are outcomes?
Objective data points
What are the three types of Surrogate Outcomes?
- Physiologic
- Biologic
- Laboratory
Example of Physiologic Surrogate measure?
BP, HR
Example of Biologic Surrogate measure?
MRI of brain and spine in MS, PET scan showing tumor high glucose metabolism
Example of Laboratory Surrogate measure?
LDL for ASCVD risk, blood tests
What some advantages of using surrogate markers?
Faster, cheaper, easier to collect.
What are some categories of outcomes?
Mortality, morbidity, quality of life, pain, others
What are three skills that go with EBP skills?
- Developing focused clinical questions
- Location applicable information
- Critically appraising information
Specific condition or outcome, patient demographic, and patient risk factors are important parts of what?
A focuses clinical question
What is the lowest and highest in the Hierarchy of Evidence?
Lowest=case reports/case series
Highest=metaanalysys
Which type of study to select and interpret diagnostic tests?
Prospective, blind comparison to gold standard
Which type of study to select therapy that does more good than harm and are worth the efforts and cost of using them? (Diagnosis)
RCT
Which type of study to estimate PT’s likely clincal course over time not based on intervention and anticipate likely complications of dz? (Prognosis)
Cohort study
Which type of study to identify cause for disease? (Harm/Etiology)
Cohort
Prospective research is when?
Researching things ahead of time
Concurrent research is when?
Researching as it happens when seeing a patient
Retrospective research is when?
Researching after asked
What is “critically appraising information”?
A process of evaluating the trustworthiness and relevance of a resource within the context of a given clinical scenario. Within a hierarchy of evidence.
What are the six steps of the EBP process?
Assess, Ask, Acquire, Appraise, Apply, Self-evaluate
Three factors for asking a focused clinical question?
- Specific condition
- Patient demographic
- Risk factors
