Exam 2 CH. 22 KIdney Flashcards

1
Q

What is Polycystic Kidney Disease

A

Enlarges kidneys, palpable mass, asymptomatic until 30s

Flank pain, headaches

75% develop HTN possible upper UTI

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2
Q

Polycystic kidney disease is autosomal ___________. And is caused by what gene

A

Dominant, PKD1 or 2 gene

Eventual renal failure

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3
Q

Saccular aneurysm mc occurs where

A

In anterior circulation, Anterior communicating artery is MC.

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4
Q

What results in worm like arteries and veins?

A

Ateriovenous Malformation

Is MC cerebrovascular malformation

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5
Q

Who’s most at risk for ateriovenous Malformation (AVM)

A

Males 2x, MC age 10-30 years old

Headaches in 50% of all cases

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6
Q

What is an occlusion of single artery

A

Lacunar infarct

It is silent and devastating

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7
Q

When a small cerebral vessel is ruptured and resorbed

A

Slit Hemorrhage

A “slit like cavity” remains

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8
Q

What occurs when diastolic BP>130 and sever ICP and global cerebral dysfunction

A

Hypertensive Encephalopathy

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9
Q

This is systemic autoimmune vasculitis, fibrinoid necrosis, small heart and arteries

A

Polyarteritis Nodosa

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10
Q

What is primary Angiitis of the CNS

A

chronic inflammation in the multiple parenchyma and subarachnoid vessels

Involves the brain and spinal cord

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11
Q

Who is most at risk for Primary Angiitis of the CNS

A

Males age 30-60

Injury from aneurysm, hemorrhage, ischemia

Treatment is Immunosuppression

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12
Q

Who is more at risk for CNS trauma

A

Males 2x more likely

The Assessment is ABCD

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13
Q

What is punch drunk?

A

Chronic Traumatic Encephalopathy CTE

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14
Q

What is most susceptible during a contusion

A

Gyri!!!!!!!!!

Coup injury- at impact site

Contrecoup injury- Opposite site of impact

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15
Q

What is it called when movement of one brain region relative to another

A

Diffuse Axonal Injury (DAI)

Severe dysfunction 50% of causes post traumatic comas

Disrupts white matter, shaking

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16
Q

How long does it take to recover from a Concussion

A

80% in 10 days without treatment

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17
Q

What is post concussive syndrome

A

When symptoms last for weeks to months

15-20% of all concussions

Fatigue/low energy= 37% MC

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18
Q

Whats so bad about second impact syndrome

A

Second concussion can occur and is LETHAL

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19
Q

This is dural ARTERY damage, compresses brain tissue, my be lucid during bleed

A

Epidural Hematoma

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20
Q

Rapid tear movements of VEIN, subdural bleed, compresses brain

A

Subdural Hematoma

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21
Q

WHich one has the dura still attached to the skull epidural or subdural

22
Q

What is the most common artery effected by an epidural hematoma

A

Middle meningeal artery

Very aggressive lethal within hours

23
Q

What is more common subdural or epidural hematoma

A

Subdural

MC self limited but still an emergency

Clot lysis 1 week, Fibrosis 1-3 months

24
Q

What is the MC CNS malformation

A

Neural tube defects 1/1000

Risks= decreased folate, previous child

25
Spina Bifida Occulta is
Bony defect, asymptomatic
26
Myelomeningocele is
Extension of CNS through vertebral defect (lumbosacral)
27
Anencephaly is
Absence of brain, roster all apsect
28
Encephalocele is
CNS diverticulum through cranium
29
Look at slide
80
30
What is Hydromyelia
Cavity, connected to 4th ventricle
31
Syringomyelia is
Aka (syrinx) Is a cyst within cord in adults Developmental or traumatic, Arnold Chiari Malf
32
What causes a "Shaw-like" distribution in the upper trunk/arms
Syringomyelia Loss of pain/temp sensation Possible tissue atrophy or areflexia
33
What is intraparenchymal hemorrhage
Prematurity, near ventricles, possible hydrocephalus
34
Infarct is
Prematurity, Supratentorial white matter, chalky plaques/necrosis, possible cysts
35
Whats cerebral Palsy
Non progressive motor neuron defects Prematurity, hypoxia, infection damage during development
36
What are symptoms of cerebral palsy
Spasticity, dystonia, ataxia, tremors 1/3 have decreased cognition or seizures
37
What is the MC CNS infection
Hematogenous, direct implant or local infection Retrograde from PNS
38
What is a Epidural Abscess
Infection in the epidural space Occurs from adjacent infection aka osteomyelitis Cord compression results is a Neurosurgical emergency
39
Whats a subdural Empyema
Infection in the subdural space Pyrexia, HA, cervicalgia Neurologic dysfunction, lethargy, coma
40
Whats meningitis
Subarachnoid inflammation of leptomeninges CSF examination helps to distinguish the type
41
what is Acute pyogenic meningitis
Rapid onset, HA, NUCHAL RIGIDITY, PHOTOPHOBIA CSF=bacteria, increased pressure, neutrophils, proteins (exudate) Fatal if untreated
42
Whats Kernig sign
Pain when moving the legs due from Meningitis
43
Whats the Brudzinski sign
When patient lays down and knees are bent they have pain when the head is lifted
44
What causes meningitis is neonates
E. Coli Group B Strep.
45
What causes meningitis in young children
Haemophilus INfluenzae
46
What causes meningitis in young adult
Neisseria meningitidis
47
What causes meningitis in older adult
Strep. Pneumoniae Listeria monocytogenes
48
What is aseptic meningitis
Viral, relatively acute onset, pyrexia, decreased consciousness, unchallenged rigidity, edema CSF= Increased Lymphocytes
49
Tuberculous meningitis is
"Tuberculoma", HA, malaise, confusion, vomiting CSF= Moderate increase in WBC's and proteins
50
Whats spirochetal meningitis
3 degree of syphilis or Lyme disease Neuronal loss, progressive loss of neuro function. Ataxia, anesthesia, Encephalopathy