Exam 2 Flashcards
What are the two types of epithelium?
Covering and lining epithelia - Skin
Glandular epithelia - secretory tissue in glands
What are the functions of the epithelium?
Protection Excretion Absorption Secretion Filtration Sensory reception
What are the five characteristics of epithelia tissue?
Polarity Specialized contacts Supported by connective tissue Avasscular Can regenerate
What are the four types of tissue?
Connective - Supports and protects
Muscular - Produces movement
Epithelium - Covers and forms lining
Nervous - Controls
What is the basement membrane?
Basal and reticular lamina
Reinforces epithelial sheet
Resists stretching and tearing
Defines epithelial boundary
How are adjacent cells bound in epithelial tissue?
Desmosomes and tight junctions
What is the reticular lamina?
Connective tissue that supports the epithelium
Deep to the basal lamina
Network of collagen fibers
What is simple epithelia?
One cell layer thick
What is stratified epithelia?
Two or more layers of cells
What are the three different cell shapes?
Squamous - flattened
Cuboidal - cubes
Columnar - columns
What are the different types of epithelia tissue?
Simple squamous Simple cuboidal Simple columnar Pseudostratified columnar Stratified squamous Stratified cuboidal Stratified columnar Transitional
What is significant about simple squamous cells and where are they located?
Allows materials to pass by diffusion and filtration
Found in kidneys, aveoli, and blood vessels
What is the endothelium?
Simple squamous tissue that lines the lymphatic vessels, blood vessels and heart
What is the mesothelium?
Simple squamous epithelium of serus membranes in ventral cavity
What is significant about simple cuboidal cells and where are they located?
Functions in secretion and absorption
Found in kidney, tubules, ovary, surface, ducts of small glands
What is significant about simple columnar cells and where are they located?
Function in absorption and secretion of mucus and enzymes
Found in digestive tract, gall bladder and excretory ducts
What is significant about pseudostratified columnar cells and where are they found?
Secrets substances, particularly mucus
Propels mucus with cilia
Found in trachea and lining bronchi into lungs
What is significant about stratified squamous cells and where are they found?
Protects underlying tissues
Found in skin, mouth and esophagus
What is significant about stratified cuboidal cells and where are they found?
Found in sweat and mammary glands
What is significant about transitional cells and where are they found?
Ability to change shape with stretch
Found in bladder
What is significant about stratified columnar cells and where are they found
Found in pharynx and male urethra
What is a gland?
One or more cells that make and secrete a secretion
What are the two types of glands?
Endocrine - ductless gland, secretion right into blood or lymph
Exocrine - Secretions released onto skin or into organs
What are unicellular glands called?
Goblet cells
What does the pancreas secrete?
Insulin (endocrine) Pancreatic juices (exocrine)
What are the three types of secretion?
Merocrine - secretes as produced, secretes by exocytosis (Pancreas, sweat glands, salivary)
Holocrine - Accumulates products within and then ruptures (oil glands)
Apocrine - Accumulates products within, but only tip ruptures (Mammary glands)
What are tubular glands?
Straight cells
What are alveolar cells?
Bulb shaped
What are the four main classes of connective tissue?
Connective tissue proper
Cartilage
Bone
Blood
What are the major functions of connective tissue?
Binds and supports Protects Transport Insulation Fuel reserve
What are the characteristics of connective tissue?
Have mesenchyme as a common tissue of origin
Have varying degree of vascularity
Have extra cellular matrix (liquid and fibers)
What are the three elements that make up connective tissue?
Ground substance
Fibers
Cells
What is the ground substance in connective tissue?
Interstitial fluid - fluid surrounding cell
Adhesion proteins
Proteoglycans
What do the fibers do in connective tissue?
Provide support
What are the three types of fibers in connective tissue?
Collagen - Thick fibers, strong structural support
Elastic - Thin stringy, allow stretch and recoil
Reticular - Strong but also allow stretch
What are the types of cells in connective tissue?
Blasts Cytes Fat cells White blood cells mast cells macrophages
What do mast cells do?
Reduce inflamation
What are the subclasses of connective tissue proper?
Loose connective tissue
Dense connective tissue
What are the characteristics of loose connective tissue?
Support and bind other tissues
Store nutrients as fat
Defend against infection
What are the subclasses of dense connective tissue?
Dense regular
Dense irregular
Elastic
What are the characteristics of dense regular tissue?
Attaches muscles to bone or muscles
Tendons and ligaments
What are the characteristics of dense irregular tissue?
Withstands tension in many directions
Joints and dermis of the skin
What are the characteristics of elastic tissue?
Allows to recoil after switching
Walls of arteries
What are the characteristics of cartilage?
Tough yet flexible
Lacks nerve fibers
Avascular
What are the types of cartilage?
Hyaline
Elastic
Fibrocartilage
What are the characteristics of hyaline cartilage?
Supports and reinforces
Serves as a resilient cushion
Covers ends of bones, ribs
What are the characteristics of elastic cartilage?
Maintains shape while allowing great flexibility
Supports external ear
What are the characteristics of fibrocartilage?
Allows to absorb compressive shock
Inter vertebral discs and knee joint
What are the characteristics of bone?
Has inorganic calcium salts
Supports and protects
Also called osseous tissue
Stores fat and synthesizes blood cells in cavities
What is the function of blood?
Transportation
What is the function of muscle?
Highly vascularized
Provides movement
What are the three types of muscle?
Skeletal - striations, multinucleated, voluntary
Cardiac - Intercalated discs, heart contractions
Smooth muscle - Involuntary, no striations, found lining hollow organs
What are neurons?
Cells that conduct and transmit electrical signals
What are neuroglia?
Supporting cells that support, insulate, and protect neurons
What is the soma?
Area where the nucleus is located in a nervous cell
What is the dendrite?
Extensions from nerve cell that pick up stimulus
What is the axon tunnel?
Tunnel on nerve cells that signals are sent down
What are the three types of membranes?
Cutaneous - skin, dry membrane
Mucous - line body cavities open to exterior, moist
Serous - found in closed body cavity, moist
What are the two ways tissue repair can occur?
Regeneration - restores original function
Fibrosis - original function lost (scars)
What tissues regenerate extremely well?
Blood Bone Epithelium Dense irregular Areolar
What tissues regenerate moderately well?
Smooth muscle
What tissues have virtually no regenerative capacity?
Cardiac and nervous
What are the three types of developmental tissue?
Ectoderm - nervous
Mesoderm - muscle
Endoderm - innner lining of digestive system
What are the two layers of the integumentary system?
Dermis - mostly fibrous connective tissue
Epidermis - superficial
What is the hypodermis?
Anchors skin to underlying structures
Mostly adipose tissue that absorbs shock and insulation
What are the four layers of the epidermis?
Stratum basale - actively dividing, house melanocytes
Stratum spinosum - House keratinocytes
Stratum granulosum
Stratum corneum - dead cells, 20-30 layers
What are melanocytes?
Store melanin that defines skin color and protects DNA from the sun
What are keratinocyctes?
Secrete keratin
What are lemellar granules?
Release lipids which help make skin water proof
What are the layers of the dermis?
Papillary
Reticular
What is the papillary layer composed of?
Areolar connective tissue
Dermal papillae
What are dermal papillae?
Thick skin lie on dermal ridges cause epidermal ridges
Enhance gripping ability
Contribute to sense of touch
Pattern is fingerprint
What is the reticular layer?
Composed of dense irregular fibrous connective tissue
What are striae?
Stretch marks
What are the three pigments that attribute to skin color?
Melanin
Caratene
Hemoglobin
What is cyanosis?
Blue skin color
Low oxygenation
What is erythema?
Redness
Caused by fever, hypertension, inflamation, allergy
What is pallor?
Paleness
Caused by anemia, low blood pressure, fear, anger
What is jaundice?
Yellow skin color
Caused by liver disorder
What is bronzing?
Metalic looking skin
Caused by inadequate steroid hormones
What are bruises?
Clotted blood underneath the skin
What is hair?
Dead keratinized cells of hard keratin
What are the functions of hair?
Physical trauma
Heat loss
Protection from sunlight
Warns off insects
What is glaborous skin?
Areas without hair
What are the two types of hair?
Vellus hair - pale, fine hair
Terminal hair - coarse, long hair of eyebrows
What area of the nail is active in nail growth?
Nail matrix
What are the two main types of sweat glands?
Eccrine
Apocrine
What are the characteristics of eccrine sweat glands?
Regulated by autonomic nervous system
Cold and heat induced sweat
What are the two types of apocrine sweat glands?
Ceruminous - lines external ear canal
Mammary glands - secrete milk
What are the functions of the integumentary system?
Protection Body temperature regulation Cutaneous sensation Metabolic functions Blood resevoir Excretion
What are the types of barriers that the integumentary system provides?
Chemical
Physical
Biological
What are examples of chemical barriers?
Skin secretions keep bacteria from growing
Melanin is a defense against UV radiation
What are the three major types of skin cancer?
Basal cell carcinoma
Squamous cell carcinoma - does matastasize
Melanoma - fast matastasize
What are the three classifications of burns?
First degree - partial thickness
Second degree - Partial thickness, blisters
Third degree - Through epidermis to dermis
What is debridement?
Removal of burned skin
What is classified as critical burns?
> 25% of body has second degree burns
10% of body has third degree burns
Face, hands or feet bear third degree burns
How does the inegumentary system develop in the fetal stage?
Ectoderm becomes the epidermis
Mesoderm becomes the dermis and hypodermis
Lanugo coat
Vernix caseasa
What is the lanugo coat?
Delicate hairs in the 5th and 6th month of fetal development
What is the vernix caseasa?
Sebaceous gland secretion
Protects skin of fetus
What are the developmental aspects that occur from infancy to adulthood?
Skin thickens, more subcutaneous fat
Sweat and sebaceous gland activity increase
Scaling and dermitis more common
What are the functions of bone?
Support Protection Movement Mineral and growth factor storage Hematopoiesis (blood cell development) Fat storage Hormone production
What is appositional growth?
Perichondrium cells secrete matrix against external face of existing cartilage
What is interstitial growth?
Chondrocytes divide and secrete new matrix, expanding cartilage from within
What are the four types of hyaline cartilage?
Articular - Covers ends of bones at moveable joints
Costal - connect ribs to sternum
Respiratory - Form skeleton of larynx and other respiratory passageways
Nasal - Supports external nose
What is the axial skeleton?
Skull
Vertebrae
Ribs
What is the appendicular skeleton?
Limbs
Attachment sites
What are the different classifications of bones based on shape?
Long bones - Longer than they are wide
Short bones - Small cube like bones (carpals)
Flat bones - Relatively thin
Irregular bones - Vertebrae and hips
What are compact bones?
Dense outer layer
Smooth and solid
What are spongy bones?
Honeycomb of flat pieces deep to compact bone
Ends of long bone
What is the shaft of a long bone called?
Diaphysis
What is the end of a long bone called?
Epiphysis
What is the epiphyseal plate?
Growing part of bone
Made of hyaline cartilage
Turns into epiphyseal line after hardening after puberty
What is the periosteum?
Outside covering of bone
What is the medullary cavity?
Inside chamber of long bone
Lined by endosteum
What is a tuberosity?
Large rounded projection
What is a crest?
Narrow ridge of bone
What is a trochanter?
Very large, blunt, irregularly shaped process
What is a line?
Narrow ridge of bone, less prominent than a crest
What is a tubercle?
Small rounded projection or process
What is an epicondyle?
Raised area on or above a condyle
What is a spine?
Sharp slender often pointed projection
What is a process?
Any bony prominence
What are the three types of bone markings?
Projections - allow for muscle and ligament attachment
Depressions
Openings
What are the five types of cells in bone?
Osteogenic cells - Make cells
Osteoblasts - Bone building cells
Osteocytes - Active osteoblasts or osteoclasts
Bone lining cells - make up periosteum and endosteum
Osteoclasts - bone resorbing cells
What is ossification?
Process of bone tissue formation
What are the two types of ossification?
Endochondial - bone forms replacing hyaline cartilage
Intramembranous - bone develops from fibrous membrane
What are the two types of postnatal bone growth?
Interstitial - lengthening of bone
Appositional - Widening of bone
What are the five zones of interstitial growth?
Resting zone
Proliferation zone - actively undergoing mitosis
Hypertrophic zone - Old cartilage cells enlarge
Calcification zone - matrix calcifies
Ossification zone - new bone formed
How do we regulate bone growth?
Growth hormone - most important
Thyroid hormone - Ensures proper proportions
Testosterone and estrogen - Promotes growth spurts
What is required for bone homeostasis?
Remodeling and bone repair
What are two ways that the body controls bone remodeling?
Negative feedback - controls calcium blood levels
Responses to mechanical and gravitational forces
What are the functions of calcium?
Nerve impulse transmission Muscle contraction Blood coagulation Cell division Secretion by glands and nerve cells
What is the function of parathyroid hormone?
Activates osteoclasts to rise blood calcium levels
What is wolff’s law?
Bones get thicker with the more stressed put on them
What is a nondisplaced fracture?
Ends of the bone retain normal position
What is a displaced fracture?
Ends of the bone are out of normal position
What is a complete fracture?
The bone is broken all the way through
What is an incomplete fracture?
The bone is not broken all the way through
What is a compound fracture?
The bone is penetrating the skin
What is a simple fracture?
The bone is not penetrating the skin
What is a compression fracture?
Bone is crushed
What is a comminuted fracture?
Bone fragments into three or more pieces
What is a spiral fracture?
Breaks occurs from excessive twisting force
What is an epiphyseal fracture?
Epiphysis and diaphysis separate along the epiphyseal plate
What is a depressed fracture?
Broken bone portion is pressed inwards
What is a greenstick fracture?
Bone bends and only one side of the bone breaks
What are the stages of bone repair?
Hematoma forms
Fibrocartilaiginous forms
Bony callus forms
Bone remodeling occurs
What is osteomalacia?
Poorly mineralized bone
Soft and weak
What is osteoporosis?
Osteoclats work faster than osteoblasts
What are the functions of joints?
Mobility
Hold skeleton together
What are the functional classifications of joints?
Synarthroses - immoveable
Amphiarthroses
Diarthroses - freely moving
What are the structural classifications of joints?
Fibrous joints
Cartilaginous joints
Synovial joints
What are the characteristics of fibrous joints?
Held together by dense fibrous connective tissue
What are the three types of fibrous joints?
Sutures
Syndemoses - immoveable joint held by ligaments
Gomphoses - Peg and socket, immoveable (teeth)
What are the two types of catilaginous joints?
Synchondroses - bones united by hyaline cartilage
Symphyses - bones united by fibrocartilage
What are the six features of synovial joints?
Articular cartilage Synovial cavity Articular capsule Synovial fluid Reinforcing ligaments Nerves and blood vessels
What are the four additional structures of synocial joints?
Fatty pads
Articular discs
Bursae
Tendon sheaths
What are fatty pads?
Serve as a cushion
What are articular discs?
Stabilize joint and improve fit
Menisci
What are bursae?
Sacs lined with synovial membrane
Reduce friction
What are tendon sheaths?
Elongated bursae wrapped around tendon subjected to friction
What are tendons?
Attach muscles to bone
What are ligaments?
Attach bone to bone
What stabilizes synovial joints?
Shapes of articular surface (minor)
Ligament number and location (Limited role)
Muscle tendons that cross joints (major role)
What are the four ranges of motion permitted by synovial joints?
Nonaxial - slipping movements only
Uniaxial - movement in one plane
Biaxial - movement in two planes
Multiaxial - movement in multiple planes
What are the six types of synovial joints?
Plane - nonaxial Hinge - uniaxial Pivot - Uniaxial Condylar - Biaxial Saddle - Biaxial Ball and socket - Multiaxial
What are the four major synovial joints?
Knee
Shoulder
Elbow
Hip
What are the two joints in the knee?
Femoropatellar - Plane joint
Lateral and medial tibiofemoral
What are the capsular and extracapsular ligaments that help stabilize the knee?
Fibular and tibial collateral ligaments
Oblique popliteal ligament
Arcuate popliteal ligament
Prevent hyperextension
What are the intrascapular ligaments that help stabilize the knee?
Anterior cruciate ligament
Posterior cruciate ligament
Prevent anterior and posterior displacement
What are the common injuries that occur to the knee?
Collateral ligaments
Cruciate ligaments
Cartilage (menisci)
What kind of joint is the shoulder joint?
Ball and socket joint
What does the coracohumeral ligament do in the shoulder?
Helps support the weight of the upper limb
What are the four rotator cuff tendons that encircle the shoulder joint?
Subscapularis
Supraspinatus
Infraspinatus
Teres minor
What does the elbow joint consist of?
Trochlear notch of the ulna with the trochlea of the humerous
Hinge joint
What are the two ligaments that help stabilize the elbow?
Anular ligament - Surrounds head of radius, allows rotation
Ulnar collateral ligament - prevents displacement of elbow
What is the acetabular labrum?
Extension of cartilage that helps hold head of femur in place
What are the ligaments that reinforce the hip?
Iliofemoral ligament
Pubofemoral ligament
Ischiofemoral ligament
Ligamentum ligament
What is the name of the joint in the jaw?
Tempromandibular joint
Allows hinge and gliding
What are the common joint injuries?
Cartilage tears - repaired by arthroscopic surgery
Sprains - Ligaments are stretched or torn
Strains - overstretching of a muscle or muscle tendon
Dislocations - luxations
Subluxation - Partial dislocation
What is bursitis?
Inflammation of bursae
What is tendonitis?
Inflammation of tendon sheaths caused by overuse
What is arthritis?
Stiffness and swelling in joints
What are the different types of arthritis?
Osteoarthritis - wear and tear
Rheumatoid - autoimmune disorder, genetic
Gouty - affects the big toe