Exam 2 Flashcards
What are the 7 functions of the skeletal system?
- protects
- supports
- movement/locomotion
- mineral storage (Ca, P)
- produces blood
- energy storage (fat stored in yellow marrow)
- hormone production (osteocalcin)
What are the 4 classifications of bones?
- long bones
- short bones
- flat bones
- irregular bones
dense outer layer of bone
compact bone
inner layer of bone; trabecular; consists of lattice of trabeculae
spongy bone
What kind of cartilage is in long bones?
articular
a bone longer than it is wide
long bone
Which type of bone has a diaphysis (shaft)?
long bones
In long bones, what does the diaphysis (shaft) contain?
medullary cavity
The medullary cavity in the diaphysis of long bones contains ____ bone marrow in infants and young children and _____ bone marrow in adults
red; yellow
ends of long bone
epiphysis
Epiphyses of long bones contain outer ____ bone and interior ___ bone
compact; spongy
The interior spongy bone in the epiphyses of long bones contains red marrow for ________, which is mainly in the head of the ________ and _______ for adults.
hematopoiesis; humerus and femur
blood cell formation
hematopoeisis
remnant of epiphyseal plate; hyaline cartilage that divides and allows the bone to grow during childhood
epiphyseal line
contains an outer fibrous layer (dense irregular CT) and an inner osteogenic layer (contains osteogenic cells that differentiate into bone cells); rich supply of nerve fibers and blood vessels pass through shaft to medullary cavity via nutrient foramina; provides attachment points for tendons and ligaments
periosteum
dense irregular CT; lines medullary cavity, central canal, Volkmann’s canal; covers trabeculae of spongy bone; contains osteogenic cells that differentiate into bone cells
endosteum
type of bone:
- spongy bone covered by compact bone
- has periosteum and endosteum
- no diaphysis or epiphyses
- diploe-spongy bone (contains red marrow - little in adult)
- ex. skull bones, sternum, scapula, and ribs
flat bones
type of bone:
- articular cartilage
- diaphysis, epiphyses
- periosteum, endosteum
long bones
type of bone:
- spongy bone covered by compact bone
- has periosteum and endosteum
- no diaphysis or epiphyses
- ex. carpals and tarsals
- sesamoid bones
short bones
bones that form within a tendon (ex. patella)
sesamoid bones
type of bone:
- spongy bone covered by compact bone
- has periosteum and endosteum
- no diaphysis or epiphyses
- ex. vertebrae and coxal (hip) bone
irregular bones
fundamental unit of bone
osteon (haversian system)
bone matrix ring
lamella
space containing the osteocyte
lacuna
transverse canals in bone
Volkmann’s canal
microscopic canals between lacunae
canaliculi
cell type of bone found in periosteum and endosteum; mitotically active; differentiate into osteoblasts
osteogenic (osteoprogentitor) cells
cell type of bone that is mitotically active; secrete bone matrix and enzymes for mineralization; mature into osteocytes
osteoblasts
(cell type of bone) mature osteoblasts; not mitotically active; do not secrete bone matrix but maintains it; communicate with and control activity of osteoblasts and osteoclasts; bone matrix breaks down if leave
osteocytes
cell type of bone that are multi-nucleated; differentiate from hematopoetic stem cells; bone re-absorption - break down bone
osteoclasts
What percent of bone tissue by mass is organic? Inorganic?
35%; 65%
What part of the bone composition includes cells (osteogenic, osteoblasts, osteocytes, osteoclasts) and the osteoid (ground substance - glycoprotein and fluid) and collagen fibers? It also gives bones flexibility and tensile strength (organic and collagen fibers)
organic
What part of the bone composition includes hydroxyapatite - calcium phosphate and contributes to the hardness of bone and bone’s ability to resist compression?
inorganic
found in and around collagen fibers in bone matrix
hydroxyapatite
The proper combination of organic and inorganic components allows bone to be ______ and _______
durable and strong without being brittle
How strong is bone in relation to steel in resisting compression? Tension?
1/2 as strong; just as strong
bone formation by becoming hard
intramembranous ossification
What is the starting material of intramembranous ossification?
mesenchyme
What is mesenchyme made up of?
embryonic connective tissue
Intramembranous ossification:
- Mesenchymal cells differentiate into _______ and cluster in the center of tissue and then differentiate into _____ (ossification center).
- Osteoblasts secrete _______ which becomes ______. They get trapped in matrix and mature into _______.
- Osteoid is laid down between blood vessels forming _____ (woven bone). _______ forms on outside of woven bone from _____.
- Just deep to periosteum, trabeculae _____. Woven bone is reshaped into _______ bone. Spongy bone remains internally and the vascular tissue becomes _______.
- osteogenic cells; osteoblasts
- osteoid; calcified; osteocytes
- trabeculae; periosteum; mesenchyme
- thickens; compact; red marrow
What is the starting material of endochondrial ossification?
hyaline cartilage
ossification in which blood vessels enter perichondrium causing osteogenic cells to differentiate into osteoblasts; perichondrium is now called periosteum
endochondrial ossification
Endochondrial ossification:
- Osteoblasts secrete osteoid around _____ of hyaline cartilage encasing it in _____.
- At _________ (center of hyaline cartilage shaft) ________ signal surrounding cartilage to calcify. ________ die. Cartilage matrix deteriorates forming _______.
- The ________ (blood vessels, nerves, red marrow, and bone cells) invades the cavity and forms _____ bone.
- Osteoclasts in center break down newly formed spongy bone creating _______. Cartilage at ______ keeps going. Cartilage along shaft calcifies, erodes, and is replaced with _______ and _______.
- ________ form at epiphyses, cartilage _______, matrix deteriorates forming _____, periosteal bud invades and forms _____ bone.
- At the end of secondary ossification, only hyaline cartilage remaining is ____ cartilage and at ____.
- diaphysis; bone-bone collar
- primary ossification center; chondrocytes; chondrocytes; cavities
- periosteal bud; spongy
- medullary cavity; ends; osteoid; hydroxiapatite
- secondary ossification centers; calcifies; cavities; spongy
- articular; epiphyseal plates
What type of bone does not have an ossification center?
short bones
4 zones of cartilage cells within the epiphyseal plate contribute to what?
postnatal bone growth
What are the 5 zones of cartilage cells within the epiphyseal plate?
- resting zone
- proliferation zone
- hypertrophic zone
- calcification zone
- ossification zone
(zone of cartilage cells within epiphyseal plate) nothing happens here
resting zone
(zone of cartilage cells within epiphyseal plate) underneath resting zone, cartilage cells undergo mitosis
proliferation zone
(zone of cartilage cells within epiphyseal plate) older cartilage cells enlarge
hypertrophic zone
(zone of cartilage cells within epiphyseal plate) matrix calcifies, cartilage cells die, matrix begins deteriorating, blood vessels invade cavity
calcification zone
(zone of cartilage cells within epiphyseal plate) new bone forms
ossification zone
coupled process of bone reabsorption and formation
bone remodeling
Bone reabsorption is due to ________ and ________.
osteoclasts; osteoblasts
deep grooves in bone; secrete lysosomes ) and hydrochloric acid
osteoclasts
secrete osteoid
osteoblasts
enzymes break down protein component of bone
lysosomes
break down inorganic component of bone
hydrochloric acid
enzymes needed for mineralization
osteoid
deficiency of vitamin D or Ca resulting in bone demineralization; bones soften and weaken; seen in adults
osteomalacia
deficiency of vitamin D or Ca; bones remain soft; bowed legs; deformities of pelvis, skull, and rib cage; seen in children
rickets
more bone reabsorption than formation; results in reduced bone mass; bones weaken and susceptible to fracture; occurs most often in older age; caused by factors such as low estrogen production such as occurs after menopause, insufficient exercise, immobility, diet low in Ca, vitamin D, protein, diabetes mellitus
osteoporosis
haphazard deposition and reabsorption of bone; activity of osteoblasts and osteoclasts become irregular; pagetic bone - newly formed bone has abnormal amount of spongy bone and can form in marrow cavities; reduced mineralization; bone thickening in areas; mostly affects spine, pelvis, femur, skull; typically only affects people over 40
paget’s disease
What are the 5 parts of the axial skeleton?
- skull
- ear ossicles
- hyoid bone
- thoracic cage
- vertebrae
What are the 3 functions of the axial skeleton?
- forms the longitudinal axis of the body
- supports the head, neck, and trunk
- protects the brain, spinal cord, and organs of thoracic cavity
How many cranial bones are there? What are they?
- frontal
- parietal (2)
- occipital
- temporal (2)
- sphenoid
- ethmoid
The cranial bones are attachment points for muscles of the _____ and ______.
head and neck
What are the 4 main sutures in the skull?
- sagittal
- lambdoid
- squamous
- coronal
key stone of skull; articulates with all other cranial bones; houses pituitary gland
sphenoid bone
between nasal and sphenoid bones; bony area between nasal cavity and orbits; contains cribriform plate, crista galli, perpendicular plate, middle and upper nasal concha
ethmoid bone
part of ethmoid bone; roof of nasal cavity; openings where olfactory nerves pass
cribriform plate
part of ethmoid bone; point of attachment for dura mater; outermost covering of the brain
crista galli
part of ethmoid bone; forms superior part of nasal septum
perpendicular plate
part of ethmoid bone; shaped like conch shell; form walls of nasal cavity
upper and middle nasal concha
How many facial bones are there? What are they?
- mandible
- vomer
- maxilla (2)
- palatine (2)
- zygomatic (2)
- lacrimal (2)
- nasal (2)
- inferior nasal concha (2)
anchors teeth
mandible
2 fused bones; anchors teeth; forms anterior part of hard palate
maxilla
cheek bones
zygomatic bones
2 medially fused bones; bridge of nose; fuses with hyaline cartilage
nasal bone
medial portion of eye socket
lacrimal bones
interior nasal septum; ethmoid also helps form nasal septum
vomer
make up lateral walls of nasal cavity along with other nasal concha
inferior nasal concha
What are the 5 functions of the facial bones?
- framework of face
- cavities for special sense organs of sight, hearing, taste, and smell
- openings for air and passage of food
- secure teeth
- anchor the facial muscles of expression (important for behavior and communication)
Bones of the skull are not fully _______ at birth.
ossified
unossified remnants of fibrous membranes; allows baby’s head to compress during birth; most replaced by bone within one year
fontanelles
only bone in body that doesn’t articulate any other bones; ligaments connect to temporal bone; attachment for tongue and some neck muscles
hyoid bone
What are the 3 parts of the ear ossicles?
- malleus (hammer)
- incus (anvil)
- stapes (stirrup)
develop from first and second pharyngeal arches in embryo; transmit and amplify sound waves
ear ossicles
What are the 3 functions of the vertebral column?
- support body
- surround and protect spinal cord
- attachment point for ribs and back muscles
Vertebrae are held together by _______
ligaments
__________ are located between vertebrae
intervertebral discs
What are the 5 parts of the vertebral column?
- cervical (neck) vertebrae
- thoracic (chest) vertebrae
- lumbar (lower back) vertebrae
- sacrum (pelvic)
- coccyx (tailbone)
How many of each type of vertebrae are there?
- cervical = 7, C1-C7
- thoracic = 12, T1-T12
- lumbar = 5, L1-L5
How many fused vertebrae are in the sacrum? Coccyx?
sacrum = 5 coccyx = 4 (bird's beak)
What type of bone is a vertebrae?
irregular
the centrum of a vertebra is also called the _____
body
projection of a vertebrae that points posteriorly
spinous process
lateral projection of a vertebrae
transverse process
large hole in the middle of a vertebrae for the spinal cord to pass through
vertebral foramen
facets on vertebrae that are covered by hyaline cartilage
superior and inferior articular processes
smallest, lightest vertebrae; have transverse foramen; spinous process bifid (except for last one)
cervical
holes in transverse processes of vertebrae
transverse foramina
C1; no body; no spinous process; superior articular faucets that articulate with occipital condyles (of occipital bone)
atlas
C2; odontoid process (dens); superior projection that allows the head to pivot; does not have transverse foramina
axis
vertebrae with a spinous process that is long and angled inferiorly; body is heart shaped; all have facets to articulate with head of ribs; aside from the last two, transverse processes have faucets that articulate with tubercles of ribs
thoracic
largest, bulkiest vertebrae; short spinous process; hatchet shaped
lumbar
The sacrum contains anterior and posterior _______
sacral foramina
tailbone; beak-shaped; gives some support for pelvic organs
coccyx
The spine of infants is ________ posteriorly (_____ curvature)
concave; primary
Cervical and lumbar vertebrae are ____ posteriorly (_______ curvature)
concave; secondary
Cervical curvature becomes prominent when infants can ______. Lumbar curvature starts when infant can ______.
lift head; walk
abnormal lateral curve of any portion of the spine - usually thoracic; treatment depends on the angle of curvature and the age or developmental status and can include wearing a back brace, or in severe cases, surgery
scoliosis
hump back; posteriorly exaggerated curvature - usually thoracic
kyphosis
exaggerated lumbar curvature; sway back
lordosis
The sternum is created by the fusion of what 3 bones?
- manubrium
- body
- xiphoid process
part of the sternum that articulates with the clavicles and ribs 1-2
manubrium
part of the sternum that articulates with ribs 2-7
body
part of the sternum that serves as an attachment point for some abdominal muscles; ossified at age 40; usually cartilage in children
xiphoid process
How many pairs of ribs do we have? True ribs? False? Floating?
12
1-7
8-12
11-12
ribs that are directly attached to the sternum by individual costal cartilages (hyaline)
true ribs
ribs that attach to the sternum indirectly by shard costal cartilages (first 3)
false ribs
ribs that have no anterior attachment
floating ribs
What is the function of the appendicular skeleton?
carry out movements
shoulder girdle; attaches left and right arms to axial skeleton; consists of scapula and clavicle
pectoral girdle
What are the 6 bones of the arm and hand?
- humerus
- radius
- ulna
- carpals
- metacarpals
- phalanges
How many carpal bones are there and what do they make up?
8; wrist
long bones that makes up the palms; how many are there?
metacarpals; 5
how many phalange bones are there? how many are in each finger?
14; 3 except thumb which has 2
wrist is concave anteriorly due to arrangement of carpals; transverse carpal ligament covers the carpals making a tunnel; many nerves and tendons; treatment includes a splint, stretches and exercises, or surgery; overuse or inflammation cause the tendons to swell and pinch nerves
carpal tunnel syndrome
hip girdle; attaches left and right legs to axial skeleton; consists of sacrum and pair of coxal bones (3 fused bones)
pelvic girdle
What are the 3 bones of the coxal bones? Where are they fused?
- ilium
- ischium
- pubis
fused at acetabulum
What is the function of the pelvic girdle?
supports all of our weight and protects internal organs
What is the difference between a male and female pelvis?
male: 1. long and narrow 2. pubic arch less than 80 degrees 3. obturator foramen is round in shape female: 1. short and wide 2. pubic arch 80-90 degrees 3. obturator foramen is oval
single bone of the thigh; largest, longest, strongest bone in the body
femur
What are the 6 main bones of the leg/foot?
- femur
- patella
- tibia
- fibula
- tarsals
- metatarsals
second largest and strongest bone in the body
tibia
site where 2 or more bones meet; the weakest part of the skeleton
joints
study of joints
arthrology
branch of medicine that deals with prevention/correction of injuries/disorders of bones, muscles associated with the skeleton, and ligaments and joints
orthopedics
What are the 2 functions of joints?
- mobility
2. cohesion
classification of joints that refers to the material binding the bones together as well as the presence/absence of a joint cavity
structural classification
What are the 3 structural classifications of joints?
- fibrous
- cartilaginous
- synovial
(structural classification of joints) dense (fibrous) CT; no joint cavity; immovable; synarthroses
fibrous
(structural classification of joints) hyaline cartilage or fibrocartilage; no joint cavity; slightly or freely moveable; amphiarthroses and diarthroses
cartilaginous
(structural classification of joints) fluid filled joint cavity; freely moveable; most of the joints in the body; diarthroses
synovial
classification of joints that refers to the amount of movement allowed
functional
What are the 3 functional classifications of joints?
- synarthroses
- amphiarthroses
- diarthroses
(functional classification of joints) immovable
synarthroses
(functional classification of joints) slightly moveable
amphiarthroses
(functional classification of joints) freely moveable
diarthroses