Exam 1 Flashcards
Explain the levels of organization in an organism.
- chemical level
- cellular level
- tissue level
- organ level
- organ system level
- organismal level
What are the three main themes of this course?
- Interconnection between structure and function
- Integrative function
- Adaptive nature of our bodies: interrelationship between environment and body response
a set of organs that performs a particular function
system
regulation of stable internal body functions
homeostasis
“to cut apart”; study of the structure of body parts and their relationships to each other
anatomy
how the body functions
physiology
- Greek physician
- 460-377 BC
- Father of Western Medicine
- First to separate disease from superstition
Hippocrates
ethical code of conduct for medical professionals
Hippocratic Oath
established the first university (The Academy); served as a mentor to Aristotle
Plato
first to perform dissection; plato’s student
Aristotle
2nd century BC; vivisections of criminals
Herophilus & Eristratus
129 AD; vivisections of pigs/primates; wrote anatomy textbook used for 1500 years
Galen
What happened during the Middle Ages?
study of anatomy was outlawed
What happened during the Renaissance?
anatomical interest/knowledge reestablished
What happened during the 17th and 18th centuries?
anatomists like celebrities; people paid to see dissections in large ampitheaters
What are the 2 subdivisions of anatomy?
gross (macroscopic)
microscopic
study of tissues
histology
study of cells
cytology
microscope that shows tissues and beyond (500000X)
scanning electron microscope
typical microscope used in lab
compound light microscope
microscope that shows cells and beyond (1000000X)
transmission electron microscope
Who is associate with the x-ray image?
Wilhelm Rontgen
In x-ray images, more dense structures show up _____.
white
In x-ray images, less dense structures show up ______.
black
diagnostic imaging tool that uses x-rays to look at the brain and abdomen
computed tomography (CT)
diagnostic imaging tool that uses sound waves and is used mostly in obstetrics
ultrasound
diagnostic imaging tool that uses radio waves and magnets to look at soft tissues
magnetic resonance imaging (MRI)
diagnostic imaging tool that uses radioactive substances to look at the brain and metabolism
positron emission tomography (PET)
two sided
bilateral
located on same side of body
ipsilateral
located on opposite sides of body
contralateral
body plane that separates anterior and posterior
frontal
- body plane that separates lateral and medial
- midline
- off midline
- sagittal
- midsagittal
- parasagittal
body plane that separates superior and inferior
transverse
What are the 2 dorsal body cavities?
- cranial (brain)
2. vertebral (spine)
What are the 2 main ventral cavities?
- thorastic
2. abdominopelvic
What are the 3 parts of the thorastic cavity?
- pleural
- mediastinum
- pericardial
What are the 2 parts of the abdominopelvic cavity?
- abdominal (digestive organs)
2. pelvic (urinary, reproductive)
What separates the abdominopelvic and thorastic cavities?
diaphram
membrane type that is thin and double-layered; lines walls of ventral body cavity and outer surfaces of organs
serosa (serous membranes)
inflammation of pleura(e)
pleurisy
inflammation of peritoneum
peritonitis
the basic structural and functional unit of the body
cell
small cells with no nucleus
red blood cells
cylindrical, multi-nucleated, long cells
skeletal muscle cells
cell body with axon and dendrites
neuron
flagellated cells
sperm cells
separates inside of cell (intracellular) from outside of cell (extracellular); controls what enters/exits cells; very thin (5-10 nanometers)
plasma/cell membrane
The lipid bilayer contains ______, _________, and _______
phospholipids
glycolipids
cholestrol
The polar head of a phospholipid is (hydrophilic/hydrophobic)
hydrophilic
The non-polar tail of a phospholipid is (hydrophilic/hydrophobic)
hydrophobic
lipids with sugar groups attached
glycolipids
dynamic assembly of saturated phospholipids, sphingolipids, and cholesterol; on outer membrane surface; important for various functions
lipid rafts
What are the 2 plasma membrane proteins?
- integral proteins
2. peripheral proteins
plasma membrane proteins that are embedded in the lipid bilayer; most are transmembrane (whole width of lipid bilayer)
integral plasma membrane proteins
What are the 5 functions of integral and peripheral plasma membrane proteins?
- transport
- receptor
- enzyme
- cell junctions
- cell identity
let certain substances pass in/out of cells
channels
substance binding; induces conformational change
carrier protein
binds substances; relays messages to interior cells
receptor
integral proteins of neighboring cells fuse together
tight junctions
like “velcro”; protein filaments extend from adjacent cells and link together
desosomes
channels of adjacent cells connect
gap junctions
signatures on cell that gives it specific identity via glycoproteins
cell identity
material between plasma membrane and nucleus
cytoplasm
What 2 things are contained in the cytoplasm?
- cytosol
2. organelles
thick, semi-transparent, jelly-like fluid; mostly water but also contains proteins, salts/irons, and sugars
cytosol
organelle that contains DNA
nucleus
organelle that performs cellular respiration; contains its own DNA
mitochondria
organelle that makes proteins
ribosomes
organelle involved in protein synthesis and packaging; has many functions
endoplasmic reticulum (rough and smooth)
organelle that is the processing center and modifies and packages proteins
golgi apparatus
organelle that serves as the cleaning crew (enzymes)
lysosomes
organelle involved in structural support and cell movements (contains microtubules and microfilaments)
cytoskeleton
affects specific enzymes found in lysosomes (specifically nerve cell enzymes); lipids accumulate; nerve cells lose function leading to death (4-5 years lifespan)
Tay Sach’s Disease
many different types; symptoms from muscle weakness to poor growth, seizures, and organ failure
mitochondrial diseases
The plasma membrane is _______ permeable.
selectively (differentially)
The way substances move across a membrane depends on the _________.
electrochemical gradient
concentration gradient + electrical gradient across plasma membrane and which direction substance needs to go
electrochemical gradient
type of transport that does not require ATP
passive transport
type of transport that requires ATP
active transport
diffusion in which substances pass through the lipid bilayer (lipid soluble molecules, small molecules)
simple diffusion
diffusion in which substances move across the membrane by protein channels or carrier proteins (glucose, amino acids, ions)
facilitated diffusion
process in which water is moving through a semi-permeable membrane (low to high concentration)
osmosis
total concentration of solutes in a solution
osmolarity
movement of solutes and water from high pressure to low pressure (faster rate than diffusion and osmosis)
bulk flow (filtration)
active transport in which large substances are transported in vesicles
bulk (vesicular) transport
bringing a substance into the cell
endocytosis
engulfing molecules/bacteria (cell eating)
phagocytosis
engulfing water (cell drinking)
pinocytosis
removing substances from the cell
exocytosis
active transport type that involves ATP and transport proteins to move substances against the concentration gradient (ex. Na+/K+ pump)
primary active transport
active transport type in which there is simultaneous movement of 2 substances through transport proteins; one provides energy to move the other
secondary active transport