exam 2 Flashcards
true or false
If performing antibody testing in infectious mononucleosis and the EBNA IgG is negative, the patient has not had a recent (acute) infection.
true
This hepatitis is known as a severe and rapidly progressive liver disease with no proven effective therapy.
HepD
The viruses polio, hepatitis A, rabies, and Japanese encephalitis are examples of ________ vaccines.
- dna
- live, attenuated
- inactivated
- virus like
inactivated
describe the correct order of vaccine development
- ID and sequence pathogen
- determine target
- conduct preclinical trials
- initial human trials
- obtain regulatory approval
- estabilish manufacturing
Which type of infection has three forms which include: lymphatic, disseminated, and respiratory
- cryptococcus
- sporotrichosis
- north american blastomycosis
- aspergillosis
sporotrichosis
Which disease has the causative agent found mainly in soil contaminated with chicken, bird, or bat excreta.
- histoplasmosis
- aspergillosis
- coccidioidomycosis
- sporotrichosis
histoplasmosis
Which is the important antibody to test in suspected causes of congenital rubella
IgM
True or False
Herpes simplex virus 2 is generally found in and around oral cavities and skin lesions above the waist.
false
herpes 2 is lower
herpes 1 is upper
True or false
In immunohistochemistry, the indirect method is more versatile than the direct method.
true
type I hypersensitivity is what kind of rxn
anaphylactic
what type of hypersensitivity reaction is cell mediated
IV
Which type of cytotoxic injury is the mechanism of injury in antibody mediated glomerulonephritis.
- antibody-dependent, compliment mediated cytotoxic rxn
- antibody-dependent, cell mediated cytotoxicity
- anti receptor antibodies
antibody-dependent, cell mediated cytotoxicity
Type IV reactions are moderated by the link between what cells
T lymphs and phagocytic cells
This type of vaccine is the closest to exposure to natural infection
live attenuated
The FTA-ABS test is a
treponemal method
Unlike some procedure, the PCR assay can be used to detect Lyme disease causing organisms in:
- urine
- CSF
- synovial fluid
- blodd
synovial fluid
One of the most common physical findings in adults with ehrlichiosis is:
fever
West Nile virus causes:
- encephalitis
- polio
- measles
- arthritis
encephalitis
Serologic procedures for the diagnosis of recent infection should include:
- only acute specimen
- only convalescent specimen
- acute and convalescent specimens
- acute, convalescent, and 6 month post infeciton specimen
acute and convalescent
Toxoplasmosis is a ___________ infection.
parasitic
Lyme disease is a _________ type of infection.
bacterial
IgG antibodies to rubella virus increase rapidly for _______ days after the acquisition of the infection.
7-21
A type II hypersensitivity reaction is a:
cytotoxic rxn
An example of a delayed nonhemolytic (type II hypersensitivity) reaction is:
graft vs host disease
