Exam 1 - Week 1 - Antitussives

Question 1

What do antitussives do in simple terms

Answer 1

Help you stop coughing

Question 2

What is the MOA of antitussives?

Answer 2

Diminish the cough reflex by direct inhibition of the cough center in the medulla.

Question 3

Name 2 antitussives.

Answer 3

1. Dextromethorphan (Delsym)

2. Benzonatate (Tessalon Perles)

Question 4

What is the MOA of benzonatate (tessalon perles)?

Answer 4

Numbs the throat

Question 5

What age is appropriate for dextromethorphan?

Answer 5

> 4 years (practitioners believe it is ineffective in kids)

Question 6

Pregnancy category of benzonatate (tessalon perles)?

Answer 6

C

Question 7

What age is appropriate for benzonatate (tessalon perles)?

Answer 7

> 10 years

Question 8

Adverse effects of antitussives?

Answer 8

Dizzy, nausea, drowsy

Question 9

Drug-drug interaction with antitussives?

Answer 9

MAOI in the last two weeks
Antidepressants
SSRIs
SNRIs
Amiodarone

Question 10

Four nursing conisderations for anititussives

Answer 10

1. May be helpful at night to decrease cough/promote sleep
2. Codeine/hydrocodone preparations no longer available d/t opioid crisis
3. Do not use in COPD or productive cough
4. Avoid the use of tessalon perles in psych pts

Question 11

What types of preparations of antitussives are available?

Answer 11

Liquid, gels, capsule, lozenges, and sublingual strips

IR and ER

Question 12

What is the onset of action for antitussives?

Answer 12

15-30 minutes