Exam 1 Vocab Flashcards
Level of biological organization:
Atoms to molecules, cells, tissues, organs, organ systems, organisms, populations, communities, ecosystems, biomes, biosphere
Theory:
An explanation of an aspect of the natural world and universe that has been repeatedly tested with the scientific method
Hypothesis:
A proposed explanation based on limited evidence
Null hypothesis:
The hypothesis is not the explanation
Independent variable
Not affected by the experiment, value does not change
Dependent variable
Changes with the experiment/ what is being tested
Control:
Provides a baseline for the experiment
Treatment groups
The item or subject that is manipulated
X- axis
Independent variable
Y-axis
Dependent variable
DNA
Deoxyribonucleic acid, stores genetic information, sugar-phosphate base
Watson & Crick
Used X-ray crystallography to determine that DNA was a double helix with antiparallel strands. Used the chargaff rule to determine nucleotides, determined nucleotides are linked through hydrogen bonding
Franklin & Wilkins
Researchers who helped Watson & Crick
RNA
Ribonucleic acid: a messenger that carries genetic information from DNA to the proteins in a cell
Hershey-Chase Experiment
Used the presence of phosphorous in DNA and sulfur in proteins ti confirm that DNA is the genetic material, not protein
Polymer
Any large molecule composed of small repeating units (monomers) bonded together
Nucleotides
A molecule consisting of a five carbon sugar, one or more phosphate groups, and a nitrogenous based
Nitrogenous base
Nitrogen containing biological compounds that form nucleosides
Purines
A class of double ringed nitrogenous bases found in nucleotides (Adenine, guanine)
Pyrimidine
A class of single-ringed nitrogenous bases found in nucleotides (Cytosine, uracil, thymine)
Sugar-phosphate backbone
The portion of the DNA double helix that provides structure and support to the molecule
Complementary base pairing
The association between specific nitrogenous based of nucleic acids stabilized by hydrogen bonding
Phospodiester linkage
Chemical linkage between adjacent nucleotides in DNA and RNA. Forms when the phosphate group of one nucleotide condenses with the hydroxyl group on the sugar of another nucleotide
Anti-parallel double helix
Describes the opposite orientation of nucleic acid strands that are hydrogen bonded to one another
Histone proteins
A member of a class of positively charged (basic) proteins associated with DNA in the chromatin of eukaryotic cells
Chromosome
Gene- carrying structure consisting of a single long molecule of double stranded DNA and associated proteins
DNA replication
The process of producing two identical replicas of DNA from the original DNA molecule
Semi-conservative
The way DNA replicates, with each strand of an existing DNA molecule serving as a template to create a new complementary DNA strand
Replication bubble
An unwound and open region of DNA where DNA replication occurs
Replication fork
The Y shaped site where a double-stranded molecule is DNA is separated into two single strands for replication and on which DNA synthesis occurs
Origin of replication
A particular sequence in a genome at which replication is initiated
Template strand
A strand of RNA or DNA used to make a new, complementary strand via complementary base pairing
Non-template strand
The strand of DNA that is not transcribed during synthesis of RNA
Leading strand
The new strand of DNA that is synthesized in one continuous piece in a direction that follows the replication fork
Lagging strand
The new strand of DNA that is synthesized discontinuously (as a series of short pieces that are later joined) in a direction moving away from the replication fork
DNA polymerase
An enzyme that catalyzes the synthesis of DNA
Central dogma
The scheme for information flow in in the cell (DNA transcription RNA translation PROTEIN)
Transcription
The process that uses a DNA template strand to produce complementary RNA
Translation
The process by which a polypeptide is synthesized from information in codons of messenger RNA
mRNA
Messenger RNA, carried information from DNA to proteins
Ribosome
A large macro molecular machine that synthesized proteins by using the genetic information encoded in mRNA
Triplet
A code in which a “word” of three letters encodes one piece of information
Codon
A sequence of 3 nucleotides in DNA or RNA that codes for an amino acid or a stop signal for protein synthesis
Amino acid
A small organic molecule with a central carbon atom bonded to an amino acid group, a carbonyl group, a hydrogen atom, and a side chain
Protein
A macromolecule consisting of one or more polypeptide chains
Polypeptide
A chain typically consisting of 50 or more amino acids linked together by peptide bonds
Enzyme
A protein catalyst used by living organisms to increase the rate of biological reactions
Start codon
The AUG triple in mRNA where protein synthesis begins; codes for the amino acid methionine
Stop codon
Any of the three mRNA triplets (UAG, UGA, or UAA) that cause the termination of protein synthesis
Base pair wobble
A pairing between two nucleotides in RNA molecules that does not follow Watson-Crick base pair rules
Gene
A section of DNA that contains the regulatory sequences and coding information for the transcription of one or more related RNA molecules, some of which encode polypeptides
Loci/locus
A gene’s physical location on a chromosome
Chromatin
The complex of DNA and proteins, mainly histones, that compose eukaryotic chromosomes.
Homologous chromosome
In diploid organisms, a member of a pair of chromosomes that are similar in size, shape, and gene content
Sister chromatid
The paired, double stranded DNA copies of a recently replicated chromosome. Connected tightly at the centromere and eventually separate during anaphase of mitosis or meiosis II
Centromere
The region of a replicated chromosome where the two sister chromatic a are joined most tightly. The kinetochore is formed during the M phase
Karyotype
The distinctive appearance of all the metaphase or prometaphase chromosomes in an individual, including the number of chromosomes, their length, and their banding patterns
Diploids
A cell or organism with two sets of chromosomes
Haploid
A cell or organism with one set of chromosomes
Gene expression
The entire set of processes, including transcription and translation, that convert the information in DNA into a product of a gene, most commonly a protein, that contributes to the phenotype of a cell organism
Genotype
The alleles of a gene present in a given individual