Exam 1 Quizes Flashcards
The best studied GAG is ____, which is secreted by cells in the lungs and other tissues in response to injury.
heparin
Although animals don’t synthesize starch, they possess an enzyme that readily hydrolyzes it. This enzyme is known as ___.
amylase
“Most often such chains are found covalently attached to lipids and proteins, converting them into glycolipids and glycoproteins.” In this sentence “chains” refer to ____.
oligosaccharides
Solid shortening, such as margarine are formed from ____ by chemically reducing the double bonds.
unsaturated vegetable oils
Not all biological polysaccharides consist of glucose monomers. An example of this is ___.
chitin
Which of the following has a carboxyl group?
A) acetic acid
B) ethyl alcohol
C) ethane
D) ethyl mercaptan
acetic acid
Which of the following is an example of a multiprotein complex?
A) myosin
B) myoglobin
C) pyruvate dehydrogenase
D) hemoglobin
E) actin
pyruvate dehydrogenase
Secondary structure is stabilized by ___. Tertiary structure is stabilized by an array of ____.
-hydrogen bonds
-non covalent bonds
Which of the following amino acid contains a sulfhydryl functional group?
A) proline
B) glycine
C) alanine
D) N-acetyglucosamine
E) cysteine
cysteine
The most widespread and important posttranslational modification is the reversible addition of a phosphate group to the following amino acids, EXCEPT ______.
lysine
Which of the following proteins constitute the machinery for biological movements?
A) antibodies and toxins
B) hormones and growth factors
C) membrane receptors and transporters
D) contractile filaments and molecular motors
E) enzymes and structural cables
contractile filaments and molecular motors
In the hemoglobin molecule of a person with sickle cell anemia, a nonpolar valine residue is present where a charged ___ is normally located.
glutamic acid
Vitamins and their derivatives often function as _____ in enzyme-catalyzed reactions.
cofactors
Which of the following is NOT true about enzymes?
A) They accelerate the rate at which a favorable reaction proceeds
B) They supply energy for a chemical reaction.
C) They are required only in small amounts.
D) They are not altered irreversibly during the course of a reaction.
E) They can participate repeatedly in individual reactions.
They supply energy for a chemical reaction.
One way to increase the reaction rate is to ____.
A) increase the energy of the reactants
B) increase the energy of the enzyme
C) increase the energy of the transition state
D) increase the activation energy
increase the energy of the reactants
The part of the enzyme molecule that is directly involved in binding the substrate is termed the ____.
active site
Which of the following will NOT accelerate a chemical reaction?
(Select 3)
A) increasing the reactivity of the substrate
B) stabilizing the the transition state
C) lowering the entropy of the substrate
D) increasing entropy of substrate
E) stabilizing the substrate
F) decreasing reactivity of substreate
stabilizing the substrate
increasing entropy of substrate
decreasing reactivity of substreate
The catalytic constant, which is the simplest measure of catalytic activity of an enzyme can be calculated from the ____.
maximal velocity
Which of the following is NOT true about enzymes?
A) They are not altered irreversibly during the course of a reaction.
B) They are required only in small amounts.
C) They can participate repeatedly in individual reactions.
D) They have no effect on the thermodynamics of the reaction.
E) They determine the ratio of products to reactants at equilibrium.
They determine the ratio of products to reactants at equilibrium.
Which of the following is not a noncovalent interaction?
A) hydrogen bond
B) peptide bond
C) ionic bond
D) hydrophilic interaction
E) hydrophobic interaction
peptide bond
The maximum number of molecules of substrate that can be converted to product by one enzyme per unit time is called ____.
turnover number
Which of the following is true?
A) The higher the delta G (i.e more positive), the faster the rate of reaction.
B) The magnitude of delta G informs us only of the difference in the free energy between the beginning state and equilibrium.
C)The magnitude of delta G is totally dependent on the time it takes to reach equilibrium.
D)The lower the delta G (i.e more negative), the faster the rate of reaction.
The magnitude of delta G informs us only of the difference in the free energy between the beginning state and equilibrium.
The term enzyme is generally reserved for ____ catalysts, while the term ____ is used for RNA catalysts.
A) inorganic, cofactor
B) protein, ribozyme
C) organic, coenzyme
D) DNA, ribosome
protein, ribozyme
Which of the following is NOT true about enzymes?
A) They can participate repeatedly in individual reactions.
B) They are not altered irreversibly during the course of a reaction.
C) They do not supply energy for a chemical reaction.
D) They are required only in small amounts.
E) They determine whether a reaction is thermodynamically favorable or unfavorable.
They determine whether a reaction is thermodynamically favorable or unfavorable.
If glucose is dissolved in water and kept sterile, it would not rapidly deteriorate because it is ___.
A) kinetically and thermodynamically stable
B) kinetically and thermodynamically unstable
C) kinetically stable, even if it is thermodynamically unstable
D) thermodynamically stable, even if it is kinetically unstable
kinetically stable, even if it is thermodynamically unstable
When a substrate enters the active site cleft, it typically gives up its ____.
A) hydrophobic environment
B) active site
C) bound water molecules
D) enzyme
E) cell
bound water molecules
The ___ provides a measure of the affinity of the enzyme for the substrate.
A) maximal velocity
B) initial reaction velocity
C) turnover number
D) Michaelis constant
E) state of saturation
Michaelis constant
Compounds formed in each step along a metabolic pathway are known as ____.
A) substrates
B) cosubstrates
C) reactants
D) end products
E) metabolites
metabolites
Glycolysis begins with the linkage of ____ to a phosphate group.
A) glucose-6-phosphate
B) starch
C) fructose-s-phosphate
D) sucrose
E) glucose
glucose
The redox reaction in glycolysis is catalyzed by ____.
A) triose phosphate isomerase
B) phosphoglyceromutase
C) aldolase
D) phosphoglycerate kinase
E) glyceraldehyde 3-phosphate dehydrogenase
glyceraldehyde 3-phosphate dehydrogenase
When oxygen levels become to low, skeletal muscle cells regenerate NAD+ by converting pyruvate to _____.
A) ethyl alcohol
B) lactate
C) acetaldehyde
D) acetyl-CoA
lactate
When cleaning with soap, greasy materials are converted into ____ that can be dispersed by water.
A) lipid bilayer
B) micelles
C) triacylglycerols
D) glycerol
E) fatty acids
micelles
Which of the following is a diacylglycerol?
A) glyceraldehyde
B) phosphatidylcholine
C) cholesterol
D) oleic acid
E) linseed oil
phosphatidylcholine
Starch is a mixture of two different polymers, _____.
amylose and amylopectin
In glyceraldehyde, carbon 2 is the ____.
A) asymmetric carbon
B) ketone
C) anomeric carbon
D) aldehyde (no)
asymmetric carbon
“If the hydroxyl group of this carbon projects to the right, the aldose is a D-sugar; if it projects to the left, it is an L-sugar.” The carbon referred to in this statement is ___.
A) asymmetric carbon associated with the aldehyde (no)
B) anomeric carbon associated with the aldehyde
C) anomeric carbon farthest from the aldehyde
D) asymmetric carbon farthest from the aldehyde
asymmetric carbon farthest from the aldehyde
Which of the following has a carbonyl group?
A) estrogen (no)
B) cholesterol
C) phosphatidylcholine
D) testosterone
testosterone
A straight-chain glucose molecule can be converted to a six-membered ring known as a ___.
A) aldose
B) furanose
C) hexose
D) pyranose
pyranose
The major component of plant cell walls is ____.
cellulose
The carboxyl group of a fatty acid is ____.
A) hydrophobic
B) saturated
C) hydrophilic
D) amphipathic
E) unsaturated
hydrophilic
Which of the following is a triacylglycerol?
A) cholesterol
B) phosphatidylcholine
C) linseed oil
D) oleic acid
E) glyceraldehyde
linseed oil
The difference between glucose and galactose is ___.
A) one is a monosaccharide, the other is a disaccharide
B) one is alpha, the other is beta
C) the configuration of the hydroxyl group in carbon 4
D) the number of asymmetric carbons
E) one is an aldose the other is a ketose
the configuration of the hydroxyl group in carbon 4
Which of the following proteins perform a wide variety of regulatory functions?
A) membrane receptors and transporters
B) hormones and growth factors
C) contractile filaments and molecular motors
D) enzymes and structural cables
E) antibodies and toxins
hormones and growth factors
Most soluble proteins are constructed so that the polar residues are situated at the ___ of the molecule.
surface
The ___ structure of a polypeptide is the specific linear sequence of amino acids that constitute the chain.
primary
A portion of a protein that is not composed of amino acids, and joined to the polypeptide chain after its assembly on the ribosome is called a ____.
prosthetic group
All amino acids have a/n _____.
A) amino group and carbonyl group
B) carbonyl group and hydroxyl group
C) carboxyl group and amino group
D) hydroxyl group and carboxyl group
E) amino group and hydroxyl group
carboxyl group and amino group
In an alpha helix, the ____ lies on the inside of the helix, and the ___ project outward.
backbone
side chains
Which of the following proteins determine what a cell reacts to and what types of substances enter or leave the cells?
A) membrane receptors and transporters
B) antibodies and toxins
C) hormones and growth factors
D) contractile filaments and molecular motors
E) enzymes and structural cables
membrane receptors and transporters
Hair is made of a large number of filaments composed of the cysteine rich protein keratin, cross-linked together by _____.
disulfide bridges
The ___ structure(s) in a protein refers to the conformation(s) of portions of the polypeptide chain.
secondary
The ____ in a protein consists of several segments of a polypeptide lying side by side.
A) amino acid
B) beta-sheet
C) peptide bond
D) disulfide bridge
E) active site
beta-sheet
Which of the following is a protein domain that mediates interaction between proteins?
A) catalytic domain
B) PH domain
C) chromodomain
D) SH3 domain
SH3 domain
All amino acids, except ____, have asymmetric carbons, and hence more than one stereoisomer.
A) proline
B) linolenic acid
C) glycine
D) N-acetyglucosamine
E) alanine
glycine
Mitochondria can fuse with one another or split in two. This splitting can be induced by ____.
A) mitosis
B) cytokinesis
C) meiosis
D) intermediate filaments
E) ER tubules
ER tubules
All of the enzymes in the TCA cycle reside in the soluble phase of the matrix, except for ____, which is bound to the inner membrane.
A) isocitrate dehydrogenase
B) succinate dehydrogenase
C) malate dehydrogenase
D) alpha-ketoglutarate dehydrogenase
succinate dehydrogenase
During the TCA cycle, four reactions occur in which a pair of electrons are transferred from a substrate to an electron accepting coenzyme. These reactions are catalyzed by ____.
A) FAD
B) NADH
C) dehydrogenases
D) coenzyme A
E) ATP
dehydrogenases
In the glycerol phosphate shuttle, electrons are transferred from NADH to ____ to form glycerol 3-phosphate, which shuttles them into the mitochondrion.
A) pyruvate
B) glycerol
C) dihydroxyacetone phosphate
D) aspartate
E) malate
dihydroxyacetone phosphate
The matrix of the mitochondrion has a gel-like consistency owing to the presence of a high concentration of _____.
A) proteins
B) carbohydrates
C) nucleic acids
D) lipids (no)
proteins